Notch通过炎性白介素信号调控肿瘤髓系来源抑制性细胞的产生和功能

31570878
2015
C0805.肿瘤免疫微环境
秦鸿雁
面上项目
教授
中国人民解放军第四军医大学
66万元
Notch信号;细胞分化;肿瘤微环境;白介素;髓系抑制性细胞
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Forced Activation of Notch in Macrophages Represses Tumor Growth by Upregulating miR-125a and Disabling Tumor-Associated Macrophages 期刊论文 Zhao JL;Huang F;He F;Gao CC;Liang SQ;Ma PF;Dong GY;Han H;Qin HY
2 Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression 期刊论文 Lin Y;Zhao JL;Zheng QJ;Jiang X;Tian J;Liang SQ;Guo HW;Qin HY;Liang YM;Han H
3 miR-148a-3p Mediates notch signaling to Promote the Differentiation and M1 activation of Macrophages 期刊论文 Huang F;Zhao JL;Wang L;Gao CC;Liang SQ;An DJ;Bai J;Chen Y;Han H;Qin HY
4 Notch signaling via Wnt regulates the proliferation of alternative, CCR2-independent tumor-associated macrophages in hepatocellular carcinoma 期刊论文 Ye YC;Zhao JL;Lu YT;Gao CC;Yang Y;Liang SQ;Lu YY;Wang L;Yue SQ;Dou KF;Qin HY;Han H
5 巨噬细胞与Wnt通路在肿瘤发生发展中的作用 期刊论文 刘明江;叶雨辰;秦鸿雁
6 Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors 期刊论文 Yang Y;Ye YC;Chen Y;Zhao JL;Gao CC;Han H;Liu WC;Qin HY
7 Myeloid-specific targeting of Notch ameliorates murine renal fibrosis via reduced infiltration and activation of bone-marrow derived macrophage 期刊论文 Jiang YL;Wang YY;Ma PF;An DJ;Zhao JL;Liang SQ;Ye YC;Lu YY;Zhang P;Liu XW;Han H;Qin HY
8 Cytotherapy with M1-polarized macrophages ameliorates liver fibrosis by modulating immune microenvironment in mice 期刊论文 Ma PF;Gao CC;Yi J;Zhao JL;Liang SQ;Zhao Y;Ye YC;Bai J;Zheng QJ;Dou KF;Han H;Qin HY
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