脾脏微环境对肿瘤诱导髓系细胞生成和免疫特性的调控与机制

91842308
2018
H1806.肿瘤免疫
郑利民
重大研究计划
教授
中山大学
300万元
髓外造血;髓系细胞;C09_肝和肝内胆管肿瘤;免疫治疗;脾脏
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Optimized Intracellular Staining Reveals Heterogeneous Cytokine Production Ability of Murine and Human Hematopoietic Stem and Progenitor Cells 期刊论文 Shufeng Luo;Huiling Lin;Lan Zhu;Hai-Tian Chen;Siqian Yang;Jinheng Li;Mingyu Liu;Limin Zheng;Chong Wu
2 Myeloid signature reveals immune contexture and predicts the prognosis of hepatocellular carcinoma 期刊论文 C Wu;Lin Jie;Y Weng;DN Zeng;J Xu;S Luo;L Xu;M Liu;Q Hua;CQ Liu;JQ Li;J Liao;C Sun;J Zhou;MS Chen;C Liu;Z Guo;SM Zhuang;JH Huang;L Zheng
3 PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen 期刊论文 M Liu;C Wu;S Luo;Q Hua;HT Chen;Y Weng;J Xu;H Lin;L Wang;J Li;L Zhu;Z Guo;SM Zhuang;T Kang;L Zheng
4 Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer 期刊论文 Chen Jing;Sun Hong-Wei;Yang Yan-Yan;Chen Hai-Tian;Yu Xing-Juan;Wu Wen-Chao;Xu Yi-Tuo;Jin Li-Lian;Wu Xiao-Jun;Xu Jing;Zheng Limin
5 PERK抑制剂在制备肝癌药物的增效剂中的应用 专利 郑利民;刘明宇;吴翀
6 一种细胞流式分析干细胞细胞因子的方法 专利 郑利民;罗舒凤;吴翀
7 C/EBPα和CD68作为预后标记物在制备肝癌预后预测试剂盒中的应用 专利 郑利民;陈敏山;王永春;许静;周仲国
8 一种基于CD11b和CD169蛋白分子的用于肝癌预后预测的标志物 专利 郑利民;吴翀;林洁;陈敏山;徐立
9 Tumor-derived adenosine promotes macrophage proliferation in human hepatocellular carcinoma 期刊论文 J Wang;Y Wang;Y Chu;Z Li;X Yu;Z Huang;J Xu;L Zheng
10 Immunosuppressive immature myeloid cell generation is controlled by glutamine metabolism in human cancer 期刊论文 WC Wu;HW Sun;J Chen;HY OuYang;XJ Yu;HT Chen;ZY Shuang;M Shi;Z Wang;L Zheng
11 CIT-H3蛋白的检测试剂在制备肝癌预后和/或复发预测试剂中的应用 专利 郑利民;蒋泽洲;吴艳
12 Carbonic anhydrase XII mediates the survival and pro-metastatic functions of macrophages in human hepatocellular carcinoma (In press. DOI: 10.1172/JCI153110) 期刊论文 WR Ning;D Jiang;XC Liu;YF Huang;ZP Peng;ZZ Jiang;T Kang;SM Zhuang;Y Wu;L Zheng
13 Neutrophil extracellular traps induce tumor metastasis through dual effects on cancer and endothelial cells 期刊论文 Ze-Zhou Jiang;Zhi-Peng Peng;Xing-Chen Liu;Hao-Fan Guo;Meng-Meng Zhou;Da Jiang;Wan-Ru Ning;Yu-Fan Huang;Limin Zheng;Yan Wu
14 Reprogramming immunosuppressive myeloid cells by activated T cells promotes the response to anti-PD-1 therapy in colorectal cancer 期刊论文 J Chen;HW Sun;YY Yang;HT Chen;XJ Yu;WC Wu;YT Xu;LL Jin;XJ Wu;J Xu;L Zheng
15 Glycolytic activation of peritumoral monocytes fosters immune privilege via the PFKFB3-PD-L1 axis in human hepatocellular carcinoma 期刊论文 DP Chen;WR Ning;ZZ Jiang;ZP Peng;LY Zhu;SM Zhuang;DM Kuang;L Zheng;Y Wu
16 Retinoic acid synthesis deficiency fosters the generation of polymorphonuclear myeloid-derived suppressor cells in colorectal cancer 期刊论文 HW Sun;J Chen;WC Wu;YY Yang;YT Xu;XJ Yu;HT Chen;Z Wang;XJ Wu;L Zheng
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