银杏内酯K通过内质网应激IRE1α介导α突触核蛋白清除的机制研究

81971194
2019
H0912.神经退行性变及相关疾病
郁文博
面上项目
副研究员
复旦大学
55万元
X-盒子结合蛋白;肌醇需要酶1α;α-突触核蛋白;帕金森病;银杏内酯K
2020-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Propagated α-synucleinopathy recapitulates REM sleep behaviour disorder followed by parkinsonian phenotypes in mice. 期刊论文 Shen Yan;Yu Wen-Bo;Shen Bo;Dong Hui;Zhao Jue;Tang Yi-Lin;Fan Yun;Yang Yan-Fei;Sun Yi-Min;Luo Su-Shan;Chen Chen;Liu Feng-Tao;Wu Jian-Jun;Xiao Bao-Guo;Yu Huan;Koprich James B;Huang Zhi-Li;Wang Jian
2 Quality of Life in Newly Diagnosed Patients With Parkin-Related Parkinson's Disease 期刊论文 Zhou Xin-Yue;Liu Feng-Tao;Chen Chen;Luo Su-Shan;Zhao Jue;Tang Yi-Lin;Shen Bo;Yu Wen-Bo;Zuo Chuan-Tao;Wu Jian-Jun;Ding Zheng-Tong;Wang Jian;Sun Yi-Min
3 Cellular and Molecular Mechanisms Underly the Combined Treatment of Fasudil and Bone Marrow Derived-Neuronal Stem Cells in a Parkinson’s Disease Mouse Model 期刊论文 Yu-Chen Yan;Yan-hua Li;Bao-Guo Xiao;Jian Wang;Jian-Ying Xi;Wen-Bo Yu
4 实验性帕金森病动物模型诱导组合物、试剂盒及用途 专利 郁文博;王坚;严雨晨;肖保国
5 银杏内酯K 在制备治疗α-突触核蛋白病的药物中的应用 专利 郁文博;王坚;严雨晨;肖保国;周宛仪
6 Uncovering the pharmacology of Ginkgo biloba folium in the cell-type-specific targets of Parkinson’s disease 期刊论文 Yu-Chen Yan;Zhi-Heng Xu;Jian Wang;Wen-Bo Yu
7 Eomesodermin in CD4(+)T cells is essential for Ginkgolide K ameliorating disease progression in experimental autoimmune encephalomyelitis 期刊论文 Chen Sheng;Zhang Juan;Yu Wen-Bo;Zhuang Jing-Cong;Xiao Wei;Wu Zhi-Ying;Xiao Bao-Guo
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