酶催化合成多重刺激响应型聚酯作为索拉非尼/miR-122联合输送载体的研究

51773231
2017
E0308.生物医用有机高分子材料
刘杰
面上项目
教授
中山大学
61万元
基因递送;药物控释;刺激响应性纳米载体;酶催化合成;功能性聚酯材料
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Thermosensitive Exosome-Liposome Hybrid Nanoparticle-Mediated Chemoimmunotherapy for Improved Treatment of Metastatic Peritoneal Cancer 期刊论文 Lv Qijun;Cheng Lili;Lu Yao;Zhang Xiaoge;Wang Yizhen;Deng Junfeng;Zhou Jiangbing;Liu Bo;Liu Jie
2 一种聚氨基酸声敏剂及其制备方法与应用 专利 刘杰;曾强;李超
3 Enzymatically synthesized poly(amino-co-ester) polyplexes for systemic delivery of pcDNA-miRNA-214 to suppress colorectal cancer liver metastasis 期刊论文 Luo Hui-yan;Yang Zhe;Wei Wei;Li Ying-qin;Pu Hengying;Chen Ya;Sheng Hui;Liu Jie;Xu Rui-hua
4 Enzymatic synthesis of PEG-poly(amine-co-thioether esters) as highly efficient pH and ROS dual-responsive nanocarriers for anticancer drug delivery 期刊论文 Gong Yi hong;Shu Man;Xie Jian hua;Zhang Chao;Cao Zhong;Jiang Zhao zhong;Liu Jie
5 Ultrasound-Assisted miR-122-Loaded Polymeric Nanodroplets for Hepatocellular Carcinoma Gene Therapy 期刊论文 Guo Huanling;Xu Ming;Cao Zhong;Li Wei;Chen Lida;Xie Xiaoyan;Wang Wei;Liu Jie
6 Gene-engineered exosomes-thermosensitive liposomes hybrid nanovesicles by the blockade of CD47 signal for combined photothermal therapy and cancer immunotherapy 期刊论文 Cheng Lili;Zhang Xiaoge;Tang Junjie;Lv Qijun;Liu Jie
7 Multifunctional FeS2 theranostic nanoparticles for photothermal-enhanced chemodynamic/photodynamic cancer therapy and photoacoustic imaging 期刊论文 Xiao Shuting;Lu Yao;Feng Miao;Dong Ming;Cao Zhong;Zhang Xiaoge;Chen You;Liu Jie
8 AMPK alpha 1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation 期刊论文 Wang Ying-Nan;Lu Yun-Xin;Liu Jie;Jin Ying;Bi Hui-Chang;Zhao Qi;Liu Ze-Xian;Li Ying-Qin;Hu Jia-Jia;Sheng Hui;Jiang Yi-Ming;Zhang Chao;Tian Feng;Chen Yang;Pan Zhi-Zhong;Chen Gong;Zeng Zhao-Lei;Liu Kai-Yan;Ogasawara Marcia;Yun Jin-Ping;Ju Huai-Qiang;Feng Jian-Xiong;Xie Dan;Gao Song;Jia Wei-Hua;Kopetz Scott;Xu Rui-Hua;Wang Feng
9 Photothermal-Enhanced Phase-Transition Nanodroplets for Ultrasound-Mediated Diagnosis and Gene Transfection 期刊论文 Gao Jinbiao;Yu Baiqing;Li Chao;Wang Wei;Xu Ming;Cao Zhong;Xie Xiaoyan;Liu Jie
10 Engineered Human Adipose Stem-Cell-Derived Exosomes Loaded with miR-21-5p to Promote Diabetic Cutaneous Wound Healing 期刊论文 Lv Qijun;Deng Junfeng;Chen You;Wang Yizhen;Liu Bo;Liu Jie
11 Enzymatic multifunctional biodegradable polymers for pH- and ROS-responsive anticancer drug delivery 期刊论文 Su Meifei;Xiao Shuting;Shu Man;Lu Yao;Zeng Qiang;Xie Jianhua;Jiang Zhaozhong;Liu Jie
12 Enzymatic synthesis of PEGylated lactide-diester-diol copolyesters for highly efficient targeted anticancer drug delivery 期刊论文 Su Meifei;Xie Jianhua;Zeng Qiang;Shu Man;Liu Jie;Jiang Zhaozhong
13 Multifunctional FeS2@SRF@BSA nanoplatform for chemo-combined photothermal enhanced photodynamic/chemodynamic combination therapy 期刊论文 Feng Miao;Li Meiting;Dai Rui;Xiao Shuting;Tang Junjie;Zhang Xiaoge;Chen Baizhu;Liu Jie
14 Combining Mechanical High-Intensity Focused Ultrasound Ablation with Chemotherapy for Augmentation of Anticancer Immune Responses 期刊论文 Li Chao;Lu Yao;Cheng Lili;Zhang Xiaoge;Yue Jun;Liu Jie
15 Immobilized Candida antarctica lipase B catalyzed synthesis of biodegradable polymers for biomedical applications 期刊论文 Lu Yao;Lv Qijun;Liu Bo;Liu Jie
16 一种氨基酸类阳离子聚合物及其制备方法和应用 专利 刘杰;刘东红;刘佳;李超
17 Ultrasound triggered phase-change nanodroplets for doxorubicin prodrug delivery and ultrasound diagnosis: An in vitro study 期刊论文 Gao Jinbiao;Yu Baiqing;Li Chao;Xu Ming;Cao Zhong;Xie Xiaoyan;Wang Wei;Liu Jie
18 Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors 期刊论文 Yang Zhe;Cheng Rui;Zhao Chenyang;Sun Na;Luo Huiyan;Chen Ya;Liu Zerong;Li Xian;Liu Jie;Tian Zhongmin
19 Galactose-modified enzymatic synthesis of poly(amino-co-ester) micelles for co-delivery miR122 and sorafenib to inhibit hepatocellular carcinoma development 期刊论文 Xie Jianhua;Lu Yao;Yu Baiqing;Wu Jun;Liu Jie
20 一种基于酶催化合成聚酯制备立构复合载药胶束的方法 专利 刘杰;曾强
21 Functionalized 2D Nb2C nanosheets for primary and recurrent cancer photothermal/immune-therapy in the NIR-II biowindow 期刊论文 Lu Yao;Zhang Xiaoge;Hou Xiuqi;Feng Miao;Cao Zhong;Liu Jie
22 Perfluorohexane-Loaded Polymeric Nanovesicles with Oxygen Supply for Enhanced Sonodynamic Therapy 期刊论文 Zeng Qlang;Qiao Lijuan;Cheng Lili;Li Chao;Cao Zhong;Chen Zhiyi;Wang Yi;Liu Jie
23 Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy 期刊论文 Shu Man;Tang Junjie;Chen Lili;Zeng Qiang;Li Chao;Xiao Shuting;Jiang Zhaozhong;Liu Jie
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