基于全基因组CRISPR/Cas9筛选系统解析人多能干细胞转变为神经上皮的细胞命运决定范式
31800858
2018
C0902.发育与衰老神经生物学
杜艳华
青年科学基金项目
助理研究员
同济大学
26万元
干细胞;转录调控网络;CRISPR/Cas9全基因组筛选;神经命运决定;神经上皮细胞
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | H3K27me3 Signal in the Cis Regulatory Elements Reveals the Differentiation Potential of Progenitors During Drosophila Neuroglial Development | 期刊论文 | Chen Xiaolong;Ye Youqiong;Gu Liang;Sun Jin;Du Yanhua;Liu Wen Ju;Li Wei;Zhang Xiaobai;Jiang Cizhong |
| 2 | Developmental programming and lineage branching of early human telencephalon | 期刊论文 | Ma Lin;Du Yanhua;Hui Yi;Li Nan;Fan Beibei;Zhang Xiaojie;Li Xiaocui;Hong Wei;Wu Zhiping;Zhang Shuwei;Zhou Shanshan;Xu Xiangjie;Zhou Zhongshu;Jiang Cizhong;Liu Ling;Zhang Xiaoqing |
| 3 | WNT/NOTCH Pathway Is Essential for the Maintenance and Expansion of Human MGE Progenitors | 期刊论文 | Ma Lin;Wang Yiran;Hui Yi;Du Yanhua;Chen Zhenyu;Feng Hexi;Zhang Shuwei;Li Nan;Song Jianren;Fang Yujiang;Xu Xiangjie;Shi Lei;Zhang Bowen;Cheng Jiayi;Zhou Shanshan;Liu Ling;Zhang Xiaoqing |
| 4 | Increase in DNA Damage by MYCN Knockdown Through Regulating Nucleosome Organization and Chromatin State in Neuroblastoma | 期刊论文 | Hu Xinjie;Zheng Weisheng;Zhu Qianshu;Gu Liang;Du Yanhua;Han Zhe;Zhang Xiaobai;Carter Daniel R;Cheung Belamy B;Qiu Andong;Jiang Cizhong |
| 5 | beta-Catenin Deletion in Regional Neural Progenitors Leads to Congenital Hydrocephalus in Mice | 期刊论文 | Ma Lin;Du Yanhua;Xu Xiangjie;Feng Hexi;Hui Yi;Li Nan;Jiang Guanyu;Zhang Xiaoqing;Li Xiaocui;Liu Ling |
| 6 | Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening | 期刊论文 | Xu Xiangjie;Du Yanhua;Ma Lin;Zhang Shuwei;Shi Lei;Chen Zhenyu;Zhou Zhongshu;Hui Yi;Liu Yang;Fang Yujiang;Fan Beibei;Liu Zhongliang;Li Nan;Zhou Shanshan;Jiang Cizhong;Liu Ling;Zhang Xiaoqing |
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