染色质环境下DNA双链断裂修复调控机制
31570813
2015
C0507.核酸生物化学
毛志勇
面上项目
教授
同济大学
60万元
DNA双链断裂修复;染色质环境;同源重组;非同源末端连接;PARP1
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | POT1 inhibits the efficiency but promotes the fidelity of nonhomologous end joining at non-telomeric DNA regions. | 期刊论文 | Yu Yang;Tan Rong;Ren Qian;Gao Boya;Sheng Zhejin;Zhang Juanlian;Zheng Xiaoqing;Jiang Ying;Li Lan;Mao Zhiyong |
| 2 | Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans. | 期刊论文 | Li Z;Zhang W;Chen Y;Guo W;Zhang J;Tang H;Xu Z;Zhang H;Tao Y;Wang F;Jiang Y;Sun F L;Mao Z |
| 3 | Nuclear cGAS suppresses DNA repair and promotes tumorigenesis. | 期刊论文 | Liu Haipeng;Zhang Haiping;Wu Xiangyang;Ma Dapeng;Wu Juehui;Wang Lin;Jiang Yan;Fei Yiyan;Zhu Chenggang;Tan Rong;Jungblut Peter;Pei Gang;Dorhoi Anca;Yan Qiaoling;Zhang Fan;Zheng Ruijuan;Liu Siyu;Liang Haijiao;Liu Zhonghua;Yang Hua;Chen Jianxia;Wang Peng;Tang Tianqi;Peng Wenxia;Hu Zhangsen;Xu Zhu;Huang Xiaochen;Wang Jie;Li Haohao;Zhou Yilong;Liu Feng;Yan Dapeng;Kaufmann Stefan H E;Chen Chang;Mao Zhiyong... |
| 4 | The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression. | 期刊论文 | Zhang F;Tang H;Jiang Y;Mao Z |
| 5 | Base excision repair but not DNA double strand break repair is impaired in aged human adipose-derived stem cells (ADSCs). | 期刊论文 | Zhang Haiping;Cai Bailian;Geng Anke;Tang Huanyin;Zhang Wenjun;Li Sheng;Jiang Ying;Tan Rong;Wan Xiaoping;Mao Zhiyong |
| 6 | Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy. | 期刊论文 | Chen Yu;Li Zhen;Xu Zhu;Tang Huanyin;Guo Wenxuan;Sun Xiaoxiang;Zhang Wenjun;Zhang Jian;Wan Xiaoping;Jiang Ying;Mao Zhiyong |
| 7 | Single senescent cell sequencing reveals heterogeneity in senescent cells induced by telomere erosion. | 期刊论文 | Tang Huanyin;Geng Anke;Zhang Tengjiao;Wang Chen;Jiang Ying;Mao Zhiyong |
| 8 | A PARP1-BRG1-SIRT1 axis promotes HR repair by reducing nucleosome density at DNA damage sites | 期刊论文 | Chen Yu;Zhang Haiping;Xu Zhu;Tang Huanyin;Geng Anke;Cai Bailian;Su Tao;Shi Jiejun;Jiang Cizhong;Tian Xiao;Seluanov Andrei;Huang Jun;Wan Xiaoping;Jiang Ying;Gorbunova Vera;Mao Zhiyong |
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