PIWI/piRNA在哺乳动物精子形成及男性不育中的功能机制
91640201
2016
C0503.细胞感应与环境生物物理
刘默芳
重大研究计划
研究员
中国科学院分子细胞科学卓越创新中心
310万元
非编码RNA表观遗传调控;基因表达;非编码RNA-蛋白质复合物;调控机制;RNA结合蛋白
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The piRNA Response to Retroviral Invasion of the Koala Genome | 期刊论文 | Yu Tianxiong;Koppetsch Birgit S;Pagliarani Sara;Johnston Stephen;Silverstein Noah J;Luban Jeremy;Chappell Keith;Weng Zhiping;Theurkauf William E |
| 2 | Piwi/piRNA调控异常与男性不育症 | 期刊论文 | 王鑫;李智彤;刘默芳 |
| 3 | Ubiquitinationdeficient Mutations in Human Piwi Cause Male Infertility by Impairing Histoneto-Protamine Exchange during Spermiogenesis | 期刊论文 | Gou LT;Dai P;Kang JY;Wang X;Li F;Zhao S;Zhang M;Hua MM;Lu Y;Zhu Y;Li Z;Chen H;Wu LG;Li D;Fu XD;Li J;Shi HJ;Liu MF |
| 4 | A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis | 期刊论文 | Dai Peng;Wang Xin;Gou Lan-Tao;Li Zhi-Tong;Wen Ze;Chen Zong-Gui;Hua Min-Min;Zhong Ai;Wang Lingbo;Su Haiyang;Wan Huida;Qian Kun;Liao Lujian;Li Jinsong;Tian Bin;Li Dangsheng;Fu Xiang-Dong;Shi Hui-Juan;Zhou Yu;Liu Mo-Fang |
| 5 | piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis | 期刊论文 | Li Feng;Yuan Peng;Rao Ming;Jin Chun-Hui;Tang Wei;Rong Ye-Fei;Hu Yun-Ping;Zhang Fengjuan;Wei Tao;Yin Qi;Liang Tingbo;Wu Ligang;Li Jinsong;Li Dangsheng;Liu Yingbin;Lou Wenhui;Zhao Shuang;Liu Mo-Fang |
| 6 | 2017年度中国生命科学十大进展 | 奖励 | 刘默芳;施惠娟 |
| 7 | LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice | 期刊论文 | Wang Xin;Li Zhi-Tong;Yan Yue;Lin Penghui;Tang Wei;Hasler Daniele;Meduri Rajyalakshmi;Li Ye;Hua Min-Min;Qi Hui-Tao;Lin Di-Hang;Shi Hui-Juan;Hui Jingyi;Li Jinsong;Li Dangsheng;Yang Jian-Hua;Lin Jinzhong;Meister Gunter;Fischer Utz;Liu Mo-Fang |
| 8 | KRAS/NF-kB/YY1/miR-489 Signaling Axis Controls Pancreatic Cancer Metastasis | 期刊论文 | Yuan P;He XH;Rong YF;Cao J;Li Y;Hu YP;Liu YB;Li DS;Lou WH;Liu MF |
| 9 | 全国妇幼健康科学技术奖 | 奖励 | 刘默芳;施惠娟;苟兰涛;戴鹏;康俊炎;王鑫;李锋 |
| 10 | 2018年度谈家桢生命科学创新奖 | 奖励 | 刘默芳 |
| 11 | Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers | 期刊论文 | Shaliu Fu;Qin Wang;Jill E Moore;Michael J Purcaro;Henry E Pratt;Kaili Fan;Cuihua Gu;Cizhong Jiang;Ruixin Zhu;Anshul Kundaje;Aiping Lu;Zhiping Weng |
| 12 | 2017年度上海市巾帼创新奖 | 奖励 | 刘默芳 |
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