NRDE2调控RNA外切体介导的RNA加工和降解的功能与分子机制研究
31770880
2017
C0507.核酸生物化学
程红
面上项目
研究员
中国科学院分子细胞科学卓越创新中心
60万元
RNA;NRDE2;外切体;hMTR4;RNA降解;RNA质量控制;复合物
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | mRNAs are sorted for export or degradation before passing through nuclear speckles | 期刊论文 | Fan Jing;Kuai Bin;Wang Ke;Wang Lantian;Wang Yimin;Wu Xudong;Chi Binkai;Li Guohui;Cheng Hong |
| 2 | Out or decay: fate determination of nuclear RNAs. | 期刊论文 | Wang Jianshu;Cheng Hong |
| 3 | 新生RNA的命运决定与调控 | 期刊论文 | 范静;王可;陈素丽;王建姝;王怡旻;程红 |
| 4 | ZFC3H1 prevents RNA trafficking into nuclear speckles through condensation. | 期刊论文 | Wang Yimin;Fan Jing;Wang Jianshu;Zhu Yi;Xu Lin;Tong Deng;Cheng Hong |
| 5 | New means to an end: mRNA export activity impacts alternative polyadenylation | 期刊论文 | Jihae Shin;Hong Cheng;Bin Tian |
| 6 | A U2-snRNP-independent role of SF3b in promoting mRNA export | 期刊论文 | Wang K;Yin CP;Du X;Chen SL;Wang JS;Zhang L;Wang LT;Yu Y;Chi BK;Shi M;Wang CS;Reed R;Zhou Y;Huang J;Cheng H |
| 7 | NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction | 期刊论文 | Wang JS;Chen JY;Wu GF;Zhang HL;Du X;Chen SL;Zhang L;Wang K;Fan J;Gao SX;Wu XD;Zhang SX;Kuai B;Zhao P;Chi BK;Wang LT;Li GH;Wong CCL;Zhou Y;Li JS;Yun CH;Cheng H |
| 8 | The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation, and mRNA export | 期刊论文 | Chen SL;Wang RJ;Zheng DH;Zhang H;Chang XY;Wang K;Li WC;Fan J;Tian B;Cheng H |
| 9 | ALYREF links 3-end processing to nuclear export of non-polyadenylated mRNAs | 期刊论文 | Fan Jing;Wang Ke;Du Xian;Wang Jianshu;Chen Suli;Wang Yimin;Shi Min;Zhang Li;Wu Xudong;Zheng Dinghai;Wang Changshou;Wang Lantian;Tian Bin;Li Guohui;Zhou Yu;Cheng Hong |
| 10 | Intronless mRNAs transit through nuclear speckles to gain export competence | 期刊论文 | Wang Ke;Wang Lantian;Wang Jianshu;Chen Suli;Shi Min;Cheng Hong |
| 11 | Structural and functional insights into R-loop prevention and mRNA export by budding yeast THO-Sub2 complex | 期刊论文 | Chen C.;Tan M.;Wu Z.;Zhang Y.;He F.;Lu Y.;Li S.;Cao M.;Li G.;Wu J.;Cheng H.;Lei M. |
| 12 | The micropeptide LEMP plays an evolutionarily conserved role in myogenesis | 期刊论文 | Wang Lantian;Fan Jing;Han Lili;Qi Haonan;Wang Yimin;Wang Hongye;Chen Suli;Du Lei;Li Sheng;Zhang Yunbin;Tang Wei;Ge Gaoxiang;Pan Weijun;Hu Ping;Cheng Hong |
| 13 | RNA结合蛋白研究技术 | 期刊论文 | 陈冠霖;王怡旻;范静;陈素丽;王建姝;王常收;张力;徐林;朱怡;张强;童登;程红 |
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