LincRNA通过编码蛋白小肽调节脂肪细胞代谢的分子机制研究
31670829
2016
C0507.核酸生物化学
丁秋蓉
面上项目
研究员
中国科学院上海营养与健康研究所
65万元
脂代谢;人多能干细胞;非编码RNA基因表达;微小开放阅读框
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Gain-of-function mutations of SLC16A11 contribute to the pathogenesis of type 2 diabetes | 期刊论文 | Yongxu Zhao;Zhuanghui Feng;Yongxian Zhang;Yingming Sun;Yanhao Chen;Xiaojian Liu;Shuang Li;Tingting Zhou;Lanlan Chen;Yuda Wei;Danjun Ma;Kathy O Liu;Yan Chen;Hao Ying;Qiurong Ding |
| 2 | MRG15 orchestrates rhythmic epigenomic remodeling and controls hepatic lipid metabolism | 期刊论文 | Yuda Wei;Cheng Tian;Yongxu Zhao;Xiaojian Liu;Feng Liu;Shuang Li;Yanhao Chen;Yan Qiu;Zhuanghui Feng;Lanlan Chen;Tingting Zhou;Xiaoguang Ren;Chengwu Feng;Yan Liu;Wenqiang Yu;Hao Ying;Qiurong Ding |
| 3 | Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression. | 期刊论文 | Zhuanghui Feng;Yuda Wei;Yongxian Zhang;Yan Qiu;Xiaojian Liu;Li Su;Ningning Liang;Huiyong Yin;Qiurong Ding |
| 4 | Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells. | 期刊论文 | Shuang Li;Mushan Li;Xiaojian Liu;Yuanyuan Yang;Yuda Wei;Yanhao Chen;Yan Qiu;Tingting Zhou;Zhuanghui Feng;Danjun Ma;Jing Fang;Hao Ying;Hui Wang;Kiran Musunuru;Zhen Shao;Yongxu Zhao;Qiurong Ding |
| 5 | 上海科技系统三八红旗手 | 奖励 | 丁秋蓉 |
| 6 | 罗丹宁衍生物在治疗代谢性疾病中的应用 | 专利 | 丁秋蓉;冯庄慧 |
| 7 | Glyburide regulates UCP1 expression in adipocytes independent of KATPchannel blockade | 期刊论文 | Yan Qiu;Yuanyuan Yang;Yuda Wei;Xiaojian Liu;Zhuanghui Feng;Xuwen Zeng;Yanhao Chen;Yan Liu;Yongxu Zhao;Lanlan Chen;Lijun Luo;Qiurong Ding |
| 8 | 吲哚满酮衍生物在治疗肥胖及其相关疾病中的应用 | 专利 | 丁秋蓉;邱艳 |
| 9 | Type 2 Diabetes Variants in the SLC16A11 coding region are not loss-of-function mutations. | 期刊论文 | Yongxu Zhao;Zhuanghui Feng;Qiurong Ding |
| 10 | Genome engineering of stem cell organoids for disease modeling | 期刊论文 | Yinming Sun;Qiurong Ding |
| 11 | Genome-scale CRISPR screening for potential targets of ginsenoside compound K | 期刊论文 | Yuanyuan Yang;Xiaojian Liu;Shuang Li;Yanhao Chen;Yongxu Zhao;Yuda Wei;Yan Qiu;Yan Liu;Zhihua Zhou;Jun Han;Guohao Wu;Qiurong Ding |
| 12 | Derivation and applications of human hepatocyte-like cells. | 期刊论文 | Shuang Li;Shiqian Huang;Yongxu Zhao;Yujie Ding;Danjun Ma;Qiurong Ding |
| 13 | Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue. | 期刊论文 | Qiu Yang;Yingmin Sun;Danqing Xu;Yuanyuan Yang;Xiaojian Liu;Yuda Wei;Yanhao Chen;Zhuanghui Feng;Shuang Li;Reyad-Ferdous M;Yongxu Zhao;Hongxi Xu;Yuanzhi Lao;Qiurong Ding |
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