【81130050】职业暴露柴油机尾气致健康损害生物标志物及其机制研究国家自然基金项目

职业暴露柴油机尾气致健康损害生物标志物及其机制研究

项目批准号： 81130050

批准年份： 2011

学科分类： H30.预防医学

项目负责人：郑玉新

资助类别：重点项目

负责人职称：教授

依托单位：中国疾病预防控制中心职业卫生与中毒控制所

资助金额： 260万元

关键词：早期效应;生物标志物;柴油机尾气;职业暴露;分子流行病学

起止时间： 2012-01-01到2016-12-31

中英文摘要
结题摘要
结题报告
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序号	标题	类型	作者
1	Effects of occupational exposure to carbon black on peripheral white blood cell counts and lymphocyte subsets	期刊论文	Rothman N\|Lan Q\|Yu S\|Zheng Y\|
2	Genetic damage induced by organic extract of coke oven emissions on human bronchial epithelial cells	期刊论文	Liu Q\|Chen W\|Ma J\|Zheng Y\|
3	AhR is negatively regulated by miR-203 in response to TCDD or BaP treatment	期刊论文	Duan, Huawei\|Zheng, Yuxin\|Wang, Qing\|Chen, Wen\|
4	焦炉逸散物致支气管上皮细胞Th17细胞因子改变	期刊论文	戴宇飞\|郑玉新\|姚林\|段化伟\|
5	应用气-液界面染毒技术研究柴油机尾气对16HBE细胞的毒性作用	期刊论文	鱼涛\|张荣\|陈雯\|郑玉新\|
6	Cytotoxicity of diesel engine exhaust among the Chinese occupational population: a complement of cytokinesis-block micronucleus cytome	期刊论文	Gao W\|Wang H\|Yu S\|Zheng Y\|
7	利用THP-1细胞进行致敏物鉴定的方法验证	期刊论文	李雪\|郑玉新\|张艳淑\|戴宇飞\|
8	Reduced pulmonary function and increased pro-inflammatory cytokines in nanoscale carbon black-exposed workers.	期刊论文	Yu Shanfa\|Yang Xiaofa\|Gao Weimin\|Zheng Yuxin\|
9	Specific histone modifications regulate the expression of AhR in 16HBE cells exposed to benzo(a)pyrene	期刊论文	Duan, Huawei\|Zheng, Yuxin\|Xiao, Yongmei\|Chen, Wen\|
10	Long-term exposure to diesel engine exhaust affects cytokine expression among occupational population	期刊论文	Jia, Xiaowei\|Wang, Haisheng\|Yu, Shanfa\|Zheng, Yuxin\|
11	Increased Micronucleus, Nucleoplasmic Bridge, and Nuclear Bud Frequencies in the Peripheral Blood Lymphocytes of Diesel Engine Exhaust-Exposed Workers	期刊论文	Niu, Yong\|Gao, Weimin\|Yu, Shanfa\|Zheng, Yuxin\|
12	焦炉逸散物对接触工人肾功能的影响	期刊论文	邢杰\|宿文革\|王春平\|段化伟\|
13	Increased levels of urinary biomarkers of lipid peroxidation products among workers occupationally exposed to diesel engine exhaust	期刊论文	Gao W\|Gu G\|Yu S\|Zheng Y\|
14	四种细胞毒性试验测定柴油机尾气颗粒物提取物急性毒性的比较	期刊论文	张哲\|段化伟\|王学生\|郑玉新\|
15	基因组高通量测序技术进展及其在预防医学中的应用	期刊论文	马俊香\|段化伟\|郑玉新\|
16	纳米级炭黑颗粒的小鼠亚急性吸入毒性研究	期刊论文	郑小美\|戴宇飞\|牛侨\|郑玉新\|
17	Increased levels of etheno-DNA adducts and genotoxicity biomarkers of long-term exposure to pure diesel engine exhaust	期刊论文	Gao, Weimin\|Yu, Shanfa\|Gu, Guizhen\|Zheng, Yuxin\|
18	Associations between DNA methylation in DNA damage response-related genes and cytokinesis-block micronucleus cytome index in diesel engine exhaust-exposed workers	期刊论文	Wang H\|Yu S\|Chen W\|Zheng Y\|
19	Global and MGMT promoter hypomethylation independently associated with genomic instability of lymphocytes in subjects exposed to high-dose polycyclic aromatic hydrocarbon	期刊论文	Zhu B\|Chen W\|Xiao Y\|Zheng Y\|
20	Long-term exposure to diesel engine exhaust induces primary DNA damage: a population-based study	期刊论文	Yu, Shanfa\|Gao, Weimin\|Chen, Wen\|Zheng, Yuxin\|
21	柴油机尾气对职业人群外周血淋巴细胞增殖能力和基因组稳定性的影响	期刊论文	张荣\|余善法\|陈雯\|郑玉新\|
22	Long-term exposure to diesel engine exhaust induced lung function decline in a cross sectional study	期刊论文	Huang CF\|Gao WM\|Yu SF\|Zheng YX\|
23	吸入染毒纳米级炭黑气溶胶致小鼠肺炎性损伤的研究.	期刊论文	孟涛\|张荣\|陈雯\|郑玉新\|
24	CpG site-specific RASSF1a hypermethylation is associated with occupational PAH exposure and genomic instability	期刊论文	Liu, Caixia\|Xiao, Yongmei\|Zheng, Yuxin\|Chen, Wen\|
25	Specific histone modifications were associated with the PAH-induced DNA damage response in coke oven workers	期刊论文	Dharmage Shyamali C.\|Dong Guanghui\|Zheng Yuxin\|Chen Wen\|
26	核酸内切酶改良型彗星实验用于检测遗传毒物致DNA氧化损伤	期刊论文	牛勇\|戴宇飞\|郑玉新\|段化伟\|

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