建立阿尔茨海默病（AD）转基因猕猴模型
81471312
2014
H0912.神经退行性变及相关疾病
胡新天
面上项目
研究员
中国科学院昆明动物研究所
150万元
转基因;动物模型;猕猴;阿尔茨海默病
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 触屏多功能非人灵长类动物认知功能测试笼 | 专利 | 吴诗昊;杨上川;胡英周;张琳恒;谭恒;吴晶;张玉华;胡新天 |
| 2 | 一种活体荧光信号的检测装置 | 专利 | 吴诗昊;何欢;雷小光;张琳恒;谭恒;李浩;胡新天 |
| 3 | A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections | 期刊论文 | Li Hao;Lei Xiaoguang;Huang Baihui;Rizak Joshua D;Yang Lichuan;Yang Shangchuan;Wu Jing;Lu Longbao;Wang Jianhong;Yan Ting;Li Hongwei;Wang Zhengbo;Hu Yingzhou;Le Weidong;Deng Xingli;Li Jiali;Xu Lin;Zhang Baorong;Hu Xintian |
| 4 | The first observation of seasonal affective disorder symptoms in Rhesus macaque | 期刊论文 | Qin Dongdong;Chu Xunxun;Feng Xiaoli;Li Zhifei;Yang Shangchuan;Lu Longbao;Yang Qing;Pan Lei;Yin Yong;Li Jiali;Xu Lin;Chen Lin;Hu Xintian |
| 5 | Cortisol responses to chronic stress in adult macaques: Moderation by a polymorphism in the serotonin transporter gene | 期刊论文 | Qin Dongdong;Rizak Joshua;Feng Xiaoli;Yang Shangchuan;Yang Lichuan;Fan Xiaona;Lue Longbao;Chen Lin;Hu Xintian |
| 6 | Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells | 期刊论文 | He Xiaping;Li Zhenhui;Rizak Joshua D;Wu Shihao;Wang Zhengbo;He Rongqiao;Su Min;Qin Dongdong;Wang Jingkun;Hu Xintian |
| 7 | Severe dopaminergic neuron loss in rhesus monkey brain impairs morphine-induced conditioned place preference | 期刊论文 | Yan Ting;Rizak Joshua Dominic;Wang Jianhong;Yang Shangchuan;Ma Yuanye;Hu Xintian |
| 8 | 猕猴触屏认知训练装置 | 专利 | 吴诗昊;段云鹏;刘益华;张玉华;谭恒;胡英周;胡新天 |
| 9 | Evidence for Conversion of Methanol to Formaldehyde in Nonhuman Primate Brain | 期刊论文 | Zhai Rongwei;Zheng Na;Rizak Joshua;Hu Xintian |
| 10 | 触屏多功能非人灵长类动物认知功能测试方法 | 专利 | 吴诗昊;杨上川;胡英周;张琳恒;谭恒;吴晶;张玉华;胡新天 |
| 11 | Alzheimer's Disease-Like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates | 期刊论文 | Rongwei Zhai;Joshua Rizak;Na Zheng;Xiaping He;Zhenhui Li;Yong Yin;Tao Su;Yingge He;Rongqiao He;Yuanye Ma;Meifeng Yang;Zhengbo Wang;Xintian Hu |
| 12 | 用于非人灵长类动物认知功能触屏测试笼的给水装置 | 专利 | 吴诗昊;杨上川;胡英周;张琳恒;谭恒;吴晶;张玉华;胡新天 |
| 13 | Neurons Differentiated from Transplanted Stem Cells Respond Functionally to Acoustic Stimuli in the Awake Monkey Brain | 期刊论文 | Wei Jing kuan;Wang Wen chao;Zhai Rong wei;Zhang Yu hua;Yang Shang chuan;Rizak Joshua;Li Ling;Xu Li qi;Liu Li;Pan Ming ke;Hu Ying zhou;Ghanemi Abdelaziz;Wu Jing;Yang Li chuan;Li Hao;Lv Long bao;Li Jia li;Yao Yong gang;Xu Lin;Feng Xiao li;Yin Yong;Qin Dong dong;Hu Xin tian;Wang Zheng bo |
| 14 | 一种活体荧光信号的记录装置 | 专利 | 吴诗昊;雷小光;何欢;谭恒;李浩;张琳恒;胡新天 |
| 15 | Comparative study of the transfection efficiency of commonly used viral vectors in rhesus monkey (Macaca mulatta) brains. | 期刊论文 | Wu Shi-Hao;Liao Zhi-Xing;D Rizak Joshua;Zheng Na;Zhang Lin-Heng;Tang Hen;He Xiao-Bin;Wu Yang;He Xia-Ping;Yang Mei-Feng;Li Zheng-Hui;Qin Dong-Dong;Hu Xin-Tian |
| 16 | Social correlates of the dominance rank and long-term cortisol levels in adolescent and adult male rhesus macaques (Macaca mulatta) | 期刊论文 | Feng Xiaoli;Wu Xujun;Morrill Ryan J;Li Zhifei;Li Chunlu;Yang Shangchuan;Li Zhaoxia;Cui Ding;Lv Longbao;Hu Zhengfei;Zhang Bo;Yin Yong;Guo Liyun;Qin Dongdong;Hu Xintian |
| 17 | The temporary and accumulated effects of transcranial direct current stimulation for the treatment of advanced Parkinson's disease monkeys | 期刊论文 | Li Hao;Lei Xiaoguang;Yan Ting;Li Hongwei;Huang Baihui;Li Ling;Xu Liqi;Liu Li;Chen Nanhui;Lu Longbao;Ma Yuanye;Xu Lin;Li Jiali;Wang Zhengbo;Zhang Baorong;Hu Xintian |
| 18 | A spontaneous depressive pattern in adult female rhesus macaques | 期刊论文 | Qin Dongdong;Rizak Joshua;Chu Xunxun;Li Zhifei;Yang Shangchuan;Lu Longbao;Yang Lichuan;Yang Qing;Yang Bo;Pan Lei;Yin Yong;Chen Lin;Feng Xiaoli;Hu Xintian |
| 19 | 一种活体荧光信号的拍照装置 | 专利 | 吴诗昊;何欢;李浩;谭恒;雷小光;张琳恒;胡新天 |
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