多肽聚合物“活体自组装”纳米探针研发及其在胰腺癌核磁共振成像诊断中的应用

51873045
2018
E0310.其他有机高分子功能材料
李莉莉
面上项目
研究员
国家纳米科学中心
60万元
多肽聚合物;核磁共振成像;活体自组装;分子探针
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A Membrane Curvature Modulated Lipopeptide to Broadly Combat Multidrug-Resistant Bacterial Pneumonia with Low Resistance Risk 期刊论文 Pengfei Zou;Jiao Liu;Xinyu Li;Muhammad Yaseen;Jiahui Yao;Lingling Liu;Lujun Luo;Hui Wang;Xinghua Shi;Zhiping Li;Tongyi Sun;Yuanyuan Gao;Chunsheng Gao;Li−Li Li
2 Recent advances: peptides and self-assembled peptide-nanosystems for antimicrobial therapy and diagnosis. 期刊论文 Pengfei Zou;Wen-Ting Chen;Tongyi Sun;Yuanyuan Gao;Li-Li Li;Hao Wang
3 Bioactivated in vivo assembly (BIVA) peptide-tetraphenylethylene (TPE) probe with controllable assembled nanostructure for cell imaging 期刊论文 Shizhao Lu;Xiaoyan Guo;Fangling Zhang;Xiaodong Li;Meishuai Zou;Li-Li Li
4 共聚物P(NIPAM-co-AAEA)的合成及其抗菌凝胶涂层的性能 期刊论文 朱凯;朱保宁;李莉莉
5 A bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging 期刊论文 Ren Han;Zeng Xiang-Zhong;Zhao Xiao-Xiao;Hou Da-yong;Yao Haodong;Yaseen Muhammad;Zhao Lina;Xu Wan-hai;Wang Hao;Li Li-Li
6 Lipase-activated glycopeptide nano-assemblies as an antibiotic nano-adjuvant to inhibit Pseudomonas aeruginosa biofilm and enhance antibacterial activity 期刊论文 Yifei Song;Jingkai Zhang;Yue Fei;Zhangjian Huang;Xiaoxuan Liu;Li-Li Li
7 Advanced nitric oxide donors: chemical structure of NO drugs, NO nanomedicines and biomedical applications. 期刊论文 Yueqi Yang;Zhangjian Huang;Li-Li Li
8 Programmable Construction of Peptide-Based Materials in Living Subjects: From Modular Design, Morphological Control to Theranostics 期刊论文 Li-Li Li;Zeng-Ying Qiao;Lei Wang;Hao Wang
9 一种SPECT影像探针及其制备方法和应用 专利 王浩;彭博;李莉莉
10 Intracellular transglutaminase-catalyzed polymerization and assembly for bioimaging of hypoxic neuroblastoma cells 期刊论文 Bo Peng;Xiao Zhao;Miao-Sen Yang;Li-Li Li
11 Rationally designed modular drug delivery platform based on intracellular peptide self-assembly 期刊论文 Hong-wei An;Muhetaerjiang Mamuti;XiaofengWang;Haodong Yao;Man-Di Wang;Lina Zhao;Li-Li Li
12 Quantitative Detection of In Vivo Aggregation Degree for Enhanced M2 Macrophage MR Imaging 期刊论文 Luo Lu-Jun;Liu Xiu-Mei;Zhang Xiao;Liu Jiao;Gao Yuanyuan;Sun Tong-Yi;Li Li-Li
13 Glycopeptide-Conjugated Aggregation-Induced Emission Luminogen: A pH-Responsive Fluorescence Probe with Tunable Self-Assembly Morphologies for Cell Imaging 期刊论文 Zhang Fangling;He Yangqing;Jin Xin;Xiang Song;Feng Hai-Tao;Li Li-Li
14 一种药物递送载体及其制备方法和应用 专利 李莉莉;李珂;郑广瑛
15 一种多肽聚集体分子及其制备方法和应用 专利 李莉莉;侯大勇;刘秀梅
16 Synthesis and Self-Assembly Behavior of Chlorophyll Derivatives for Ratiometric Photoacoustic Signal Optimization. 期刊论文 Jin Zhou;Zi-Jun Gao;Jun-Quan Cai;Li-Li Li;Hao Wang
17 Bacteria-Instructed In Situ Aggregation of AuNPs with Enhanced Photoacoustic Signal for Bacterial Infection Bioimaging. 期刊论文 Shi-Zhao Lu;Xiao-Yan Guo;Mei-Shuai Zou;Zi-Qin Zheng;Yu-Chuan Li;Xiao-Dong Li;Li-Li Li;Hao Wang
18 Chlorophylls derivatives: Photophysical properties, assemblies, nanostructures and biomedical applications 期刊论文 Jun-Quan Cai;Xiu-Mei Liu;Zi-Jun Gao;Li-Li Li;Hao Wang
19 Self-assembled nanomaterials: design principles, the nanostructural effect, and their functional mechanisms as antimicrobial or detection agents 期刊论文 Li-Li Li;Hong-Wei An;Bo Peng;Rui Zheng;Hao Wang
20 一种活体自组装MRI成像探针及其制备方法和应用 专利 李莉莉;刘秀梅;王浩
21 A ratiometric photoacoustic imaging approach for semi-quantitative determination of aggregation efficiency in vivo 期刊论文 Bo Peng;Xiu-Mei Liu;Hsian-Rong Tseng;Li-Li Li;Hao Wang
22 Peptide-based nano-antibiotic transformers with antibiotic adjuvant effect for multidrug resistant bacterial pneumonia therapy 期刊论文 Jiao Liu;Xiao Zhang;Pengfei Zou;Jiahui Yao;Lingling Liu;Yun Cai;Tongyi Sun;Yuanyuan Gao;Li-Li Li
23 Glycopeptide-nanotransforrs eyedrops with enhanced permeability and retention for preventing fundus neovascularization 期刊论文 Li Ke;Li Ruxiang;Zou Pengfei;Li Li;Wang Huajun;Kong Deqian;Zheng Guangying;Li Li-Li
24 Identification of New Nitric Oxide-Donating Peptides with Dual Biofilm Eradication and Antibacterial Activities for Intervention of Device-Related Infections 期刊论文 Yue Fei;Jianbing Wu;Hong-Wei An;Kai Zhu;Bo Peng;Junquan Cai;Yihua Zhang;Li-Li Li;Hao Wang;Zhangjian Huang
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