基于动态动力学拆分合成手性非环核苷

21778014
2017
B0702.生物分子的化学生物学
谢明胜
面上项目
教授
河南师范大学
65万元
抗病毒活性;手性非环核苷;手性亲核催化剂;核苷;动态动力学拆分
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 通过嘌呤、醛和酸酐的动态动力学拆分合成手性嘌呤非环核苷的方法 专利 谢明胜;陈阳光;武晓霞;渠桂荣;郭海明
2 动态动力学拆分α-芳基-α-烷基羧酸酯的方法及应用 专利 谢明胜;连赛雅;李宁;武晓霞;渠桂荣;郭海明
3 Chemo- and regioselective ring-opening of donor–acceptor oxiranes with N-heteroaromatics 期刊论文 Ji-Wei Sang;Ming-Sheng Xie;Man-Man Wang;Gui-Rong Qu;Hai-Ming Guo
4 一种合成喷昔洛韦类似物的方法 专利 郭海明;谢明胜;梁涛;王海霞;王东超;渠桂荣
5 手性3-氨基-4-芳基吡啶氮氧类催化剂及其在四氮唑半缩醛胺酯反应中的应用 专利 谢明胜;王笑冰;单梦;武晓霞;渠桂荣;郭海明
6 Dynamic Kinetic Resolution of Carboxylic Esters Catalyzed by Chiral PPY N-Oxides: Synthesis of Nonsteroidal Anti-Inflammatory Drugs and Mechanistic Insights 期刊论文 Ming-Sheng Xie;Ning Li;Yin Tian;Xiao-Xia Wu;Yun Deng;Gui-Rong Qu;Hai-Ming Guo
7 Scandium-Triflate-Catalyzed Regioselective Ring Opening of Purines with Aminocyclopropanes 期刊论文 Tao Liang;Ming-Sheng Xie;Gui-Rong Qu;Hai-Ming Guo
8 Enantioselective rearrangement of indolyl carbonates catalyzed by chiral DMAP-N-oxides 期刊论文 Meng Shan;Tao Liang;Ye-Fei Zhang;Ming-Sheng Xie;Gui-Rong Qu;Hai-Ming Guo
9 Synthesis of Chiral Acyclic Nucleosides by Sharpless Asymmetric Dihydroxylation: Access to Cidofovir and Buciclovir 期刊论文 Qin Tao;Li Jian-Ping;Xie Ming-Sheng;Qu Gui-Rong;Guo Hai-Ming
10 Dynamic Kinetic Resolution of α-Purine Substituted Alkanoic Acids: Access to Chiral Acyclic Purine Nucleosides 期刊论文 Huifang Zhang;Mingsheng Xie;Guirong Qu;Junbiao Chang
11 一种通过共轭加成-质子化反应合成含硫侧链的手性嘧啶非环核苷的方法 专利 谢明胜;郭海明;王东超;王海霞;李建平;脱灏然;渠桂荣
12 Enantioselective and regiodivergent allylation of pyrimidines with terminal allenes: an approach to pyrimidine acyclic nucleosides 期刊论文 Liang Lei;Niu Hong-Ying;Xie Ming-Sheng;Qu Gui-Rong;Guo Hai-Ming
13 一种合成替诺福韦类似物的方法 专利 谢明胜;郭海明;张慧芳;渠桂荣
14 3,4-二氨基吡啶氮氧类手性催化剂及其在Steglich重排中的应用 专利 谢明胜;单梦;张业飞;武晓霞;渠桂荣;郭海明
15 Synthesis of Chiral Acyclic Pyrimidine Nucleosides with a Sulfur-Containing Side Chain via Enantioselective Tandem Conjugate Addition/Protonation 期刊论文 Li Jian-Ping;Tuo Hao-Ran;Xie Ming-Sheng;Kang Bo;Qu Gui-Rong;Guo Hai-Ming
16 Rational Design of 2-Substituted DMAP-N-oxides as Acyl Transfer Catalysts: Dynamic Kinetic Resolution of Azlactones 期刊论文 Ming-Sheng Xie;Bin Huang;Ning Li;Yin Tian;Xiao-Xia Wu;Yun Deng;Gui-Rong Qu;Hai-Ming Guo
17 一种合成抗病毒药物西多福韦中间体和布昔洛韦中间体的方法 专利 谢明胜;秦涛;郭海明;李建平;王东超;王海霞;张齐英;渠桂荣
18 手性3,4-二氨基吡啶氮氧类催化剂催化吲哚碳酸酯重排的方法 专利 谢明胜;李宁;单梦;张业飞;武晓霞;渠桂荣;郭海明
19 Chiral 4-Aryl-pyridine-N-oxide Nucleophilic Catalysts: Design, Synthesis, and Application in Acylative Dynamic Kinetic Resolution 期刊论文 Ming-Sheng Xie;Meng Shan;Ning Li;Yang-Guang Chen;Xiao-Bing Wang;Xuan Cheng;Yin Tian;Xiao-Xia Wu;Yun Deng;Gui-Rong Qu;Hai-Ming Guo
20 Asymmetric Synthesis of Chiral Acyclic Purine Nucleosides Containing a Hemiaminal Ester Moiety via Three-Component Dynamic Kinetic Resolution 期刊论文 Ming-Sheng Xie;Yang-Guang Chen;Xiao-Xia Wu;Gui-Rong Qu;Hai-Ming Guo
21 Efficient synthesis of tetrazole hemiaminal silyl ethers via three-component hemiaminal silylation 期刊论文 Ming-Sheng Xie;Xuan Cheng;Yang-Guang Chen;Xiao-Xia Wu;Gui-Rong Qu;Hai-Ming Guo
22 Chiral DMAP-N-oxides as Acyl Transfer Catalysts: Design, Synthesis, and Application in Asymmetric Steglich Rearrangement 期刊论文 Ming-Sheng Xie;Ye-Fei Zhang;Meng Shan;Xiao-Xia Wu;Gui-Rong Qu;Hai-Ming Guo
23 2,4-二氨基吡啶氮氧类催化剂及其在吖内酯醇解开环中的应用 专利 谢明胜;李宁;黄斌;武晓霞;渠桂荣;郭海明
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享