多靶细胞垂钓结合事件驱动迭代反馈的药对协同增效成分群发现及配比优化

81873185
2018
H3303.中西医结合研究新技术与新方法
李飞
面上项目
教授
新疆医科大学
56万元
缺失/捕获技术;事件驱动;协同增效成分组合;配伍规律;配比优化
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Osthole: a potential AMPK agonist that inhibits NLRP3 inflammasome activation by regulating mitochondrial homeostasis for combating rheumatoid arthritis 期刊论文 Xiao-li Jiang;Zhuo-jian Lu;Qian Zhang;Jia-lin Yu;Dong Han;Jin-hong Liu;Ping Li;Fei Li
2 Network Pharmacology-Based Analysis on the Effects and Mechanism of the Wang-Bi Capsule for Rheumatoid Arthritis and Osteoarthritis 期刊论文 Shan-Shan Wu;Li-Jun Hao;Yifeng Shi;Zhuo-Jian Lu;Jia-Lin Yu;Si-Qi Jiang;Qing-Ling Liu;Ting Wang;Shuwen Guo;Ping Li;Fei Li
3 LSEC、Raw264.7、Hepa1-6 三种鼠源细胞系cGAS-STING 信号 通路的本底表达及激活研究 期刊论文 周钰婷;张勇;杨建;李飞
4 筛选药对活性成分及其配比优化的方法 专利 李飞;徐茜茜;李萍
5 中药活性成分发现与作用机制研究 奖励 李飞;常军民;潘婷
6 天然药物活性成分发现与生物功能评价 奖励 李飞
7 一种防治类风湿关节炎和/或骨关节炎的组合物及应用 专利 李飞;蒋小丽;于佳琳;李萍
8 Homotherapy for heteropathy active components and mechanisms of Qiang-Huo-Sheng-Shi decoction for treatment of rheumatoid arthritis and osteoarthritis 期刊论文 Yuan-Yuan Shi;Ying-Qi Li;Xiang Xie;Yu-Ting Zhou;Qian Zhang;Jia-Lin Yu;Ping Li;Na Mi;Fei Li
9 Medioresinol as a novel PGC-1 alpha activator prevents pyroptosis of endothelial cells in ischemic stroke through PPAR alpha-GOT1 axis 期刊论文 Wang Yunjie;Guan Xin;Gao Cheng-Long;Ruan Wenchen;Zhao Shunyi;Kai Guoyin;Li Fei;Pang Tao
10 Thermal and wine processing enhanced Clematidis Radix et Rhizoma ameliorate collagen Ⅱ induced rheumatoid arthritis in rats 期刊论文 Si-Qi Jiang;Ting Pan;Jia-Lin Yu;Ying Zhang;Ting Wang;Ping Li;Fei Li
11 A carrier-free anti-inflammatory platinum (II) self-delivered nanoprodrug for enhanced breast cancer therapy 期刊论文 Xing Lei;Yang Chen-Xi;Zhao Di;Shen Li-Jun;Zhou Tian-Jiao;Bi Yu-Yang;Huang Zhang-Jian;Wei Qiong;Li Ling;Li Fei;Jiang Hu-Lin
12 System pharmacology analysis to decipher the effect and mechanism of active ingredients combination from herb couple on rheumatoid arthritis in rats 期刊论文 Shan-Shan Wu;Xiaoqiang Xu;Yuan-Yuan Shi;Yi Chen;Li Ying;Si-Qi Jiang;Tingyu Wang;Peng Li;Fei Li
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