Beclin 1-VPS34复合体对神经细胞内β淀粉样蛋白稳态的调控作用及机制研究

31500831
2015
C0901.分子与细胞神经生物学
路嘉宏
青年科学基金项目
副研究员
珠海澳大科技研究院
19万元
1-VPS34;Beclin;阿尔茨海默病;自噬;β淀粉样蛋白;复合体;β淀粉样蛋白前体蛋白
2016-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models 期刊论文 Yang Chuanbin;Cai Cui-Zan;Song Ju-Xian;Tan Jie-Qiong;Durairajan Siva Sundara Kumar;Iyaswamy Ashok;Wu Ming-Yue;Chen Lei-Lei;Yue Zhenyu;Li Min;Lu Jia-Hong
2 Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurodegenerative diseases 期刊论文 Wang Sheng-Fang;Wu Ming-Yue;Cai Cui-Zan;Li Min;Lu Jia-Hong
3 Selective autophagy: The new player in the fight against neurodegenerative diseases? 期刊论文 Wu Ming-Yue;Song Ju-Xian;Wang Sheng-Fang;Cai Cui-Zan;Li Min;Lu Jia-Hong
4 Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity 期刊论文 Wu Ming-Yue;Wang Sheng-Fang;Cai Cui-Zan;Tan Jie-Qiong;Li Min;Lu Jin-Jian;Chen Xiu-Ping;Wang Yi-Tao;Zheng Wei;Lu Jia-Hong
5 Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death 期刊论文 Wang Sheng-Fang;Liu Liang-Feng;Wu Ming-Yue;Cai Cui-Zan;Su Huanxing;Tan Jieqiong;Lu Jia-Hong;Li Min
6 Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology 期刊论文 Ningning Yuan;Jia-Hong Lu
7 Neuroprotective effects of baicalein in animal models of Parkinson's disease: A systematic review of experimental studies 期刊论文 Qi Zhu;Xuxu Zhuang;Jiahong Lu
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