手性青霉胺纳米多肽抑制金属离子诱导的Aβ纤维化聚集及机制研究

21401002
2014
B0702.生物分子的化学生物学
孙冬冬
青年科学基金项目
副教授
安徽农业大学
25万元
金属螯合剂;手性纳米颗粒;Aβ聚集;青霉胺;阿尔兹海默病
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Antibacterial activity of ruthenium(II) polypyridyl complex manipulated by membrane permeability and cell morphology 期刊论文 Sun Dongdong;Zhang Weiwei;Lv Mengting;Yang Endong;Zhao Qian;Wang Weiyun
2 Investigation of antibacterial activity and related mechanism of a ruthenium(II) polypyridyl complex 期刊论文 Sun Dongdong;Zhang Weiwei;Yang Endong;Li Nuan;Liu Haiping;Wang Weiyun
3 Chiral penicillamine-modified selenium nanoparticles enantioselectively inhibit metal-induced amyloid beta aggregation for treating Alzheimer's disease 期刊论文 Sun Dongdong;Zhang Weiwei;Yu Qianqian;Chen Xu;Xu Meng;Zhou Yanhui;Liu Jie
4 Design of PLGA-functionalized quercetin nanoparticles for potential use in Alzheimer's disease 期刊论文 Sun Dongdong;Li Nuan;Zhang Weiwei;Zhao Zhiwei;Mou Zhipeng;Huang Donghui;Liu Jie;Wang Weiyun
5 Silver nanoparticles-quercetin conjugation to siRNA against drug-resistant Bacillus subtilis for effective gene silencing: in vitro and in vivo 期刊论文 Sun Dongdong;Zhang Weiwei;Li Nuan;Zhao Zhiwei;Mou Zhipeng;Yang Endong;Wang Weiyun
6 Quercetin-loaded PLGA nanoparticles: a highly effective antibacterial agent in vitro and anti-infection application in vivo 期刊论文 Sun Dongdong;Li Nuan;Zhang Weiwei;Yang Endong;Mou Zhipeng;Zhao Zhiwei;Liu Haiping;Wang Weiyun
7 一种由CdSe/ZnS量子点修饰的槲皮素抗菌药物及其制备方法 专利 孙冬冬;张伟伟;李暖;杨恩东;汪维云
8 Selective nuclei accumulation of ruthenium(II) complex enantiomers that target G-quadruplex DNA 期刊论文 Sun Dongdong;Liu Yanan;Yu Qianqian;Liu Du;Zhou Yanhui;Liu Jie
9 Anti-tumor activity and mechanism of apoptosis of A549 induced by ruthenium complex 期刊论文 Sun Dongdong;Mou Zhipeng;Li Nuan;Zhang Weiwei;Wang Yazhe;Yang Endong;Wang Weiyun
10 Transcriptome Analysis Reveals Silver Nanoparticle-Decorated Quercetin Antibacterial Molecular Mechanism 期刊论文 Sun Dongdong;Zhang Weiwei;Mou Zhipeng;Chen Ying;Guo Feng;Yang Endong;Wang Weiyun
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