淀粉样蛋白病理性聚集及αB-crystallin内源性蛋白对其调控机制的分子模拟研究

11904189
2019
A2012.液态、准晶与非晶态物理
孙运祥
青年科学基金项目
副教授
宁波大学
23万元
高分子和聚合物;淀粉样病理性聚集;天然无序蛋白;多肽多肽相互作用;分子动力学模拟
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 A buried glutamate in the cross-beta core renders beta-endorphin fibrils reversible 期刊论文 Yuying Liu;Yu Zhang;Yunxiang Sun;Feng Ding
2 Molecular Insights into the Misfolding and Dimerization Dynamics of the Full-Length α-Synuclein from Atomistic Discrete Molecular Dynamics Simulations 期刊论文 Yu Zhang;Ying Wang;Yuying Liu;Guanghong Wei;Feng Ding;Yunxiang Sun
3 Hydroxylated single-walled carbon nanotube inhibits β2m21-31 fibrillization and disrupts pre-formed proto-fibrils. 期刊论文 Yu Zhang;Yuying Liu;Wenhui Zhao;Yunxiang Sun
4 Molecular Insights into the Self‐Assembly of Block Copolymer Suckerin Polypeptides into Nanoconfined β‐Sheets 期刊论文 Yuying Liu;Ying Wang;Chaohui Tong;Guanghong Wei;Feng Ding;Yunxiang Sun
5 Misfolding and Self-Assembly Dynamics of Microtubule-Binding Repeats of the Alzheimer-Related Protein Tau 期刊论文 Huan He;Yuying Liu;Yunxiang Sun;Feng Ding
6 αB-Crystallin Chaperone Inhibits Aβ Aggregation by Capping the β-Sheet-Rich Oligomers and Fibrils 期刊论文 Yunxiang Sun;Feng Ding
7 Spontaneous Formation of β-sheet Nano-barrels during the Early Aggregation of Alzheimer's Amyloid Beta. 期刊论文 Yunxiang Sun;Aleksandr Kakinen;Xulin Wan;Niamh Moriarty;Cameron P.J.Hunt;Yuhuan Li;Nicholas Andrikopoulos;Aparna Nandakumar;Thomas P.Davis;Clare L. Parish;Yang Song;Puchun Ke;Feng Ding
8 Structural Perturbation of Monomers Determines the Amyloid Aggregation Propensity of Calcitonin Variants 期刊论文 Yuying Liu;Ying Wang;Yu Zhang;Yu Zou;Guanghong Wei;Feng Ding;Yunxiang Sun
9 Molecular Insights into the Oligomerization Dynamics and Conformations of Amyloidogenic and Non-Amyloidogenic Amylin from Discrete Molecular Dynamics Simulations 期刊论文 Ying Wang;Yuying Liu;Yu Zhang;Guanghong Wei;Feng Ding;Yunxiang Sun
10 Direct Observation of beta-Barrel Intermediates in the Self-Assembly of Toxic SOD1(28-38) and Absence in Nontoxic Glycine Mutants 期刊论文 Yunxiang Sun;Junchao Huang;Xiangmei Duan;Feng Ding
11 Thermo- and pH-Responsive Fibrillization of Squid Suckerin A1H1 Peptide 期刊论文 Yunxiang Sun;Feng Ding
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享