肠道菌群通过SCFAs/GPCRs免疫途径对小鼠帕金森模型神经保护的机制研究
81801276
2018
H0912.神经退行性变及相关疾病
乔晨萌
青年科学基金项目
讲师
江南大学
21万元
粪菌移植;SCFAs/GPCRs;短链脂肪酸;帕金森病;免疫途径
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Sodium Butyrate Causes alpha-Synuclein Degradation by an Atg5-dependent and PI3K/Akt/mTOR-related Autophagy Pathway | 期刊论文 | Chen-Meng Qiao;Meng-Fei Sun;Xue-Bing Jia;Yun Shi;Bo-Ping Zhang;Zhi-Lan Zhou;Li-Ping Zhao;Chun Cui;Yan-Qin Shen |
| 2 | Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson's disease mouse model | 期刊论文 | Zhou Yu;Zhao Wei-Jiang;Quan Wei;Qiao Chen-Meng;Cui Chun;Hong Hui;Shi Yun;Niu Gu-Yu;Zhao Li-Ping;Shen Yan-Qin |
| 3 | 隔日禁食对帕金森病模型小鼠肠道屏障的保护作用及机制 | 期刊论文 | 张博枰;赵丽萍;石芸;洪慧;周玉;周芝兰;贾雪冰;乔晨萌;赵炜疆;崔春;申延琴 |
| 4 | Protective Effects of Prucalopride in MPTP-induced Parkinson's Disease Mice: Neurochemistry, Motor function and gut barrier | 期刊论文 | Yun Shi;Chen-Meng Qiao;Yu Zhou;Ji Wu;Chu Cui;Hui Hong;Xue-Bing Jia;Shu-Bing Huang;Li Yao;Wei-Jiang Zhao;Yan-Qin Shen |
| 5 | Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model | 期刊论文 | Chen-Meng Qiao;Meng-Fei Sun;Xue-Bing Jia;Yang Li;Bo-Ping Zhang;Li-Ping Zhao;Yun Shi;Zhi-Lan Zhou;Ying-Li Zhu;Chun Cui;Yan-Qin Shen |
| 6 | Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish | 期刊论文 | Li-Ping Zhao;Bo-Ping Zhang;Shu-Bing Huang;Zhi-Lan Zhou;Xue-Bing Jia;Chen-Meng Qiao;Fang Wang;Meng-Fei Sun;Yun Shi;Li Yao;Chun Cui;Yan-Qin Shen |
| 7 | Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites | 期刊论文 | Zhi-Lan Zhou;Xue-Bing Jia;Meng-Fei Sun;Ying-Li Zhu;Chen-Meng Qiao;Bo-Ping Zhang;Li-Ping Zhao;Qin Yang;Chun Cui;Xue Chen;Yan-Qin Shen |
| 8 | Anti-inflammation Effect and The Mechanism of Suitable Concentration of Short-chain Fatty Acids Mixture on Microglia | 期刊论文 | Xue-Bing Jia;Zhi-Lan Zhou;Bo-Ping Zhang;Li-Ping Zhao;Chen-Meng Qiao;Meng-Fei Sun;Xiu-Lan Sun;Yong-Quan Chen;Chun Cui;Yan-Qin Shen |
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