粪菌移植通过TLR4-NFκB途径对小鼠帕金森病模型的神经保护机制
81771384
2017
H0912.神经退行性变及相关疾病
申延琴
面上项目
教授
江南大学
54万元
粪菌移植;肠道菌群;帕金森病;TLR4-NFκB;神经炎症
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Vancomycin pretreatment on MPTP-induced Parkinson's disease mice exerts neuroprotection by suppressing inflammation both in brain and gut | 期刊论文 | Chun Cui;Hui Hong;Yun Shi;Yu Zhou;Chen-Meng Qiao;Wei-Jiang Zhao;Li-Ping Zhao;Jian Wu;Wei Quan;Gu-Yu Niu;Yi-Bo Wu;Chao-Sheng Li;Li Cheng;Yan Hong;Yan-Qin Shen |
| 2 | 鼠李糖乳杆菌对斑马鱼脊髓损伤后肠道炎症的抑制作用及其机制 | 期刊论文 | 赵丽萍;黄术兵;张博枰;周芝兰;贾雪冰;孙孟菲;乔晨萌;陈雪;申延琴;崔春 |
| 3 | Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites | 期刊论文 | Zhou Zhi Lan;Jia Xue Bing;Sun Meng Fei;Zhu Ying Li;Qiao Chen Meng;Zhan Bo Ping;Zhao Li Ping;Yang Qin;Cui Chun;Chen Xue;Shen Yan Qin |
| 4 | 小鼠下丘脑和海马组织神经干细胞的蛋白质组学分析 | 期刊论文 | 贾雪冰;孙孟菲;姚莉;刘畅;董茵;黄日祥;柏亮;唐晨;申延琴;崔春 |
| 5 | Insulin-Like Growth Factor-1 Enhances Motoneuron Survival and Inhibits Neuroinflammation After Spinal Cord Transection in Zebrafish | 期刊论文 | Zhao Liping;Zhang Boping;Huang Shubing;Zhou Zhilan;Jia Xuebing;Qiao Chenmeng;Wang Fang;Sun Mengfei;Shi Yun;Yao Li;Cui Chun;Shen Yanqin |
| 6 | Sodium butyrate causes alpha-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway | 期刊论文 | Qiao Chen-Meng;Sun Meng-Fei;Jia Xue-Bing;Shi Yun;Zhang Bo-Ping;Zhou Zhi-Lan;Zhao Li-Ping;Cui Chun;Shen Yan-Qin |
| 7 | Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model | 期刊论文 | Qiao Chen-Meng;Sun Meng-Fei;Jia Xue-Bing;Li Yang;Zhang Bo-Ping;Zhao Li-Ping;Shi Yun;Zhou Zhi-Lan;Zhu Ying-Li;Cui Chun;Shen Yan-Qin |
| 8 | Anti-inflammation Effect and The Mechanism of Suitable Concentration of Short-chain Fatty Acids Mixture on Microglia | 期刊论文 | Jia Xue Bing;Zhou Zhi Lan;Zhang Bo Ping;Zhao Li Ping;Qiao Chen Meng;Sun Meng Fei;Sun Xiu Lan;Chen Yong Quan;Cui Chun;Shen Yan Qin |
| 9 | Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson's disease mice: Gut microbiota, glial reaction and TLRLI/TNF-alpha signaling pathway | 期刊论文 | Sun Meng Fei;Zhu Ying Li;Zhou Zhi Lan;Jia Xue Bing;Xu Yi Da;Yang Qin;Cui Chun;Shen Yan Qin |
| 10 | 隔日禁食对帕金森病模型小鼠肠道屏障的保护作用及机制 | 期刊论文 | 张博枰;赵丽萍;石芸;洪慧;周玉;周芝兰;贾雪冰;乔晨萌;赵炜疆;崔春;申延琴 |
| 11 | Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury | 期刊论文 | Chun Cui;Lin-Fang Wang;Shu-Bing Huang;Peng Zhao;Yong-Quan Chen;Yi-Bo Wu;Chen-Meng Qiao;Wei-Jiang Zhao;Yan-Qin Shen |
| 12 | Activating Transcription Factor 6 Contributes to Functional Recovery After Spinal Cord Injury in Adult Zebrafish | 期刊论文 | Zhe Ji;Zhi-Lan Zhou;Qin Hao;Lin Zhao;Chun Cui;Shu-Bing Huang;Yan-Ling Yang;Yan-Qin Shen |
| 13 | Protective effects of prucalopride in MPTP-induced Parkinson & rsquo;s disease mice: Neurochemistry, motor function and gut barrier | 期刊论文 | Shi Yun;Qiao Chen-Meng;Zhou Yu;Wu Ji;Cui Chun;Hong Hui;Jia Xue-Bing;Huang Shu-Bing;Yao Li;Zhao Wei-Jiang;Shen Yan-Qin |
| 14 | Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, alpha-synuclein expression and oxidative stress | 期刊论文 | Zhu Ying Li;Sun Meng Fei;Jia Xue Bing;Cheng Kun;Xu Yi Da;Zhou Zhi Lan;Zhang Pei Hao;Qiao Chen Meng;Cui Chun;Chen Xue;Yang Xu Sheng;Shen Yan Qin |
| 15 | Dysbiosis of gut microbiota and microbial metabolites in Parkinson's Disease | 期刊论文 | Sun Meng Fei;Shen Yan Qin |
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