白念珠菌质膜蛋白Rch1对细胞质内钙离子稳态和耐药调控功能的机理研究

81371784
2013
H2202.病原真菌与感染
蒋伶活
面上项目
教授
江南大学
70万元
耐药;酿酒酵母菌;钙离子稳态;RCH1;白念珠菌
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Expression of NYV1 encoding the negative regulator of Pmc1 is repressed by two transcriptional repressors, Nrg1 and Mig1 期刊论文 Zhao Yunying;Xiong Bing;Xu Huihui;Jiang Linghuo
2 Genetic interactions between Rch1 and the high-affinity calcium influx system Cch1/Mid1/Ecm7 in the regulation of calcium homeostasis, drug tolerance, hyphal development and virulence in Candida albicans 期刊论文 Xu Dayong;Cheng Jianqing;Cao Chunlei;Wang Litong;Jiang Linghuo
3 The putative ABC transporter encoded by the orf19.4531 plays a role in the sensitivity of Candida albicans cells to azole antifungal drugs 期刊论文 Jiang Linghuo;Xu Dayong;Chen Zhen;Cao Yongbing;Gao Pinghui;Jiang Yuanying
4 Cadmium induces the activation of cell wall integrity pathway in budding yeast 期刊论文 Xiong Bing;Zhang Lilin;Xu Huihui;Yang Yi;Jiang Linghuo
5 The Candida albicans plasma membrane protein Rch1p, a member of the vertebrate SLC10 carrier family, is a novel regulator of cytosolic Ca2+ homoeostasis. 期刊论文 Jiang L;Alber J;Wang J;Du W;Li X;Geyer J
6 弱化乙醇途径关键酶活性减少酿酒酵母在丙酮酸发酵过程中副产物乙醇的积累 期刊论文 吴满珍;李鹏越;苏珂;徐国强;蒋伶活
7 CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form in Candida albicans 期刊论文 Feng Jinrong;Duan Yinong;Sun Wei;Qin Yongwei;Zhuang Zhong;Zhu Dandan;Sun Xiaolei;Jiang Linghuo
8 Vcx1-D1 (M383I), the Vcx1 mutant with a calcineurin-independent vacuolar Ca2+/H+ exchanger activity, confers calcineurin-independent Mn2+ tolerance in Saccharomyces cerevisiae 期刊论文 Zhao Yunying;Xu Huihui;Zhang Yan;Jiang Linghuo
9 白念珠菌细胞内钙离子稳态和钙离子/钙调磷酸酯酶信号途径的调控机理研究进展 期刊论文 徐大勇;蒋伶活
10 A “Selector” based workflow facilitating SCRaMbLEd advantageous strain selection. 期刊论文 Luo Z;Wang L;Wang Y;Zhang W;Guo Y;Zhou Y;Dong J;Shen Y;Jiang L;Wu Q;Zhang C;Cai Y;Dai J
11 Cadmium-induced activation of high osmolarity glycerol pathway through its Sln1 branch is dependent on the MAP kinase kinase kinase Ssk2, but not its paralog Ssk22, in budding yeast. 期刊论文 Jiang L;Cao C;Zhang L;Lin W;Xia J;Xu H;Zhang Y
12 CaRch1p does not functionally interact with the high-affinity Ca2+ influx system (HACS) of Candida albicans 期刊论文 Alber Joerg;Jiang Linghuo;Geyer Joachim
13 The transcription cofactor FgSwi6 plays a role in growth and development, carbendazim sensitivity, cellulose utilization, lithium tolerance, deoxynivalenol production and virulence in the filamentous fungus Fusarium graminearum 期刊论文 Liu Ningning;Fan Feiyu;Qiu Dewen;Jiang Linghuo
14 The putative transcription factor CaRtg3 is involved in tolerance to cations and antifungal drugs as well as serum-induced filamentation in Candida albicans 期刊论文 Yan Hongbo;Zhao Yunying;Jiang Linghuo
15 白念珠菌CaGDT1基因的功能研究 期刊论文 王军军;王雅楠;徐大勇;蒋伶活
16 酿酒酵母细胞中内质网应激与未折叠蛋白反应的研究进展 期刊论文 赵运英;王琦;袁凡;蒋伶活
17 酿酒酵母中与ScRch1定位相关的膜蛋白和脂质体蛋白的筛选 期刊论文 赵 刚;曹春蕾;赵运英;蒋伶活
18 The N-terminal pY33XL motif of CaPsy2 is critical for the function of protein phosphatase 4 in CaRad53 deactivation, DNA damage-induced filamentation and virulence in Candida albicans. 期刊论文 Feng J;Duan Y;Qin Y;Sun W;Zhuang Z;Zhu D;Jiang L
19 Genetic interactions between the Golgi Ca2+/H+ exchanger Gdt1 and the plasma membrane calcium channel Cch1/Mid1 in the regulation of calcium homeostasis, stress response and virulence in Candida albicans 期刊论文 Wang Yanan;Wang Junjun;Cheng Jianqing;Xu Dayong;Jiang Linghuo
20 Site-saturation engineering of proline 474 in pyruvate carboxylase from Rhizopus oryzae to elevate fumaric acid production in engineered Saccharomyces cerevisiae cells 期刊论文 Xu Guoqiang;Wu Manzhen;Jiang Linghuo
21 The plasma membrane protein Rch1 is a negative regulator of cytosolic calcium homeostasis and positively regulated by the calcium/calcineurin signaling pathway in budding yeast 期刊论文 Zhao Yunying;Yan Hongbo;Happeck Ricardo;Peiter-Volk Tina;Xu Huihui;Zhang Yan;Peiter Edgar;Triplet Chloe van Oostende;Whiteway Malcolm;Jiang Linghuo
22 Genome-scale genetic screen of lead ion-sensitive gene deletion mutations in Saccharomyces cerevisiae 期刊论文 Du J.;Cao C.;Jiang L.
23 白念珠菌细胞内钙离子稳态和钙离子/钙调磷酸酯酶信号途径的调控机理研究进展 期刊论文 徐大勇;蒋伶活
24 酿酒酵母中与钙离子稳态调控因子ScRCH1细胞质膜定位相关的转录因子基因的筛选检测 期刊论文 杜敬彩;曹春蕾;赵刚;赵运英;蒋伶活
25 白念珠菌CaFIG1基因缺失突变株的构建 期刊论文 王雅楠;王军军;徐大勇;蒋伶活
26 The endosomal sorting complex required for transport (ESCRT) is required for the sensitivity of yeast cells to nickel ions in Saccharomyces cerevisiae 期刊论文 Luo Chong;Cao Chunlei;Jiang Linghuo
27 酿酒酵母中SSK2基因与其他镉耐受相关基因之间的双基因缺失菌株构建 期刊论文 熊兵;杨益;蒋伶活
28 酵母细胞内离子稳态的调控机制 期刊论文 赵运英;徐慧慧;张艳;蒋伶活
29 The transcription factor Ace2 and its paralog Swi5 regulate ethanol production during static fermentation through their targets Cts1 and Rps4a in Saccharomyces cerevisiae 期刊论文 Wu Yao;Du Jie;Xu Guoqiang;Jiang Linghuo
30 酿酒酵母细胞基因组中与转录因子Rim101亚细胞定位相关的磷酸酶和激酶基因的筛选 期刊论文 张艳;王頔;赵运英;蒋伶活
31 白念珠菌CaCSC1基因的敲除和功能研究 期刊论文 杨益;王亚楠;蒋伶活
32 Vcx1 and ESCRT components regulate intracellular pH homeostasis in the response of yeast cells to calcium stress 期刊论文 Papouskova Klara;Jiang Linghuo;Sychrova Hana
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