肠道微生物调控GLP-1R对精神分裂症伴代谢综合征的作用机制
81871051
2018
H1005.精神分裂症及精神病性障碍
陈剑华
面上项目
研究员
上海市精神卫生中心
56万元
精神分裂症;肠道微生物;代谢综合征;GLP-1受体
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 抗精神病药物诱发代谢综合征的DNA甲基化研究进展 | 期刊论文 | 项思莹;李宁宁;徐一峰;陈剑华 |
| 2 | Histone deacetylase 4 inhibition ameliorates the social deficits induced by Ephrin-B2 mutation | 期刊论文 | Peijun Ju;Jianhua Chen;Le Ma;Ying Cheng;Jiwei Liu;Ying Sun;Cuizhen Zhu;Zhe Shen;Wei wang;Yanmin Peng;Usman Ali;Nanjie Xu;Jinghong Chen |
| 3 | Patient health questionnaire-15 (PHQ-15) to distinguish bipolar II disorder from major depressive disorder | 期刊论文 | Daliang Sun;Qinghe Liu;Meijuan Li;Yuan Yang;Ran Zhang;Min Li;Siying Xiang;Jianhua Chen |
| 4 | 抗精神病药物所致代谢综合征与中医常见疗法的研究进展 | 期刊论文 | 项思莹;陈剑华;陈熤;徐一峰 |
| 5 | Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study | 期刊论文 | Jianhua Chen;Ping Yang;Qian Zhang;Ruirui Chen;Peng Wang;Benxiu Liu;Wensheng Sun;Xuemin Jian;Siying Xiang;Juan Zhou;Ningning Li;Ke Wang;Chengwen Gao;Yanqin Wen;Chuanhong Wu;Jinmai Zhang;Yalin Zhao;Qiangzhen Yang;Meihang Li;Robert Stewart;Yuanchao Sun;Dun Pan;Yujuan Niu;Zhuo Wang;Yifeng Xu;Xingwang Li;Lin He;Zhiqiang Li;Yongyong Shi |
| 6 | Identification of rare and common variants in BNIP3L: a schizophrenia susceptibility gene | 期刊论文 | Juan Zhou;Chuanchuan Ma;Ke Wang;Xiuli Li;Xuemin Jian;Han Zhang;Jianmin Yuan;Jiajun Yin;Jianhua Chen;Yongyong Shi |
| 7 | 中药复方治疗抗精神病药物所致代谢综合征的用药规律和潜在作用机制研究 | 期刊论文 | 罗超;涂斯婧;李宁宁;鞠培俊;徐一峰;陈剑华 |
| 8 | 肠道菌群与抗精神病药所致代谢综合征相关研究进展 | 期刊论文 | 李宁宁;项思莹;徐一峰;陈剑华 |
| 9 | Cigarette smoking and schizophrenia: Mendelian randomisation study | 期刊论文 | Jianhua Chen;Ruirui Chen;Siying Xiang;Ningning Li;Chengwen Gao;Chuanhong Wu;Qian Zhang;Yalin Zhao;Yanhui Liao;Robert Stewart;Yifeng Xu;Yongyong Shi;Zhiqiang Li |
| 10 | SNX29, a new susceptibility gene shared with major mental disorders in Han Chinese population | 期刊论文 | Jian-Hua Chen;Ying Zhao;Raja Amjad Waheed Khan;Zhi-Qiang Li;Juan Zhou;Jia-Wei Shen;Si-Ying Xiang;Ning-Ning Li;Zu-Jia Wen;Xue-Min Jian;Zhi-Jian Song;Robert Stewart;Zhuo Wang;Dun Pan;Lin He;Yi-Feng Xu;Yong-Yong Shi |
| 11 | Network pharmacology-based exploration of therapeutic mechanism of Liu-Yu-Tang in atypical antipsychotic drug-induced metabolic syndrome | 期刊论文 | Ning-Ning Li;Si-Ying Xiang;Xin-Xin Huang;Yu-Ting Li;Chao Luo;Pei-Jun Ju;Yi-Feng Xu;Jian-Hua Chen |
| 12 | CDH23基因突变在垂体腺瘤分子诊断中的应用 | 专利 | 赵曜;黄传新;师咏勇;张启麟;宋智建;马增翼;陈剑华;寿雪飞;叶钊;王镛斐;李士其;张逸超;宋剑平;陈峻叡;沈越;王晔 |
| 13 | BRAF基因检测物在制备ACTH型垂体腺瘤分子病理诊断及分型产品中的应用 | 专利 | 师咏勇;赵曜;黄传新;陈剑华;宋智健;马增翼;张启麟;间学敏;李士其;王镛斐;叶红英;叶钊 |
| 14 | 改良道家认知疗法对男性残留型精神分裂症患者阴性症状及认知功能改善作用的研究 | 期刊论文 | 陆如平;高慧;彭红;沈怡;戴晶璟;顾燕;陈剑华 |
| 15 | 一种用于氯氮平个体化用药指导的基因检测试剂、试剂盒、检测方法及应用 | 专利 | 李志强;师咏勇;陈剑华;高成文;陈瑞瑞 |
| 16 | The comorbidity of mental and physical disorders with self-reported chronic back or neck pain: Results from the China Mental Health Survey | 期刊论文 | Yifeng Xu;Wang Yan;Jianhua Chen;Yanling He;Qingzhi Zeng;Yueqin Huang;Xiufeng Xu;Jin Lu;Zhizhong Wang;Xian Sun;Jing Chen;Feng Yan;Tao Li;Wanjun Guo;Guangming Xu;Hongjun Tian;Xiangdong Xu;Yanjuan Ma;Limin Wang;Mei Zhang;Yongping Yan;Bo Wang;Shuiyuan Xiao;Liang Zhou;Lingjiang Li;Yan Zhang;Hongguang Chen;Tingting Zhang;Jie Yan;Hua Ding;Yaqin Yu;Changgui Kou;Fu-Jun Jia;Liu Jian;Zheli Chen;Ning Zhang;Xinbai Du;Xiangdong Du... |
| 17 | Network pharmacology-based identification for therapeutic mechanism of Ling-Gui-Zhu-Gan decoction in the metabolic syndrome induced by antipsychotic drugs | 期刊论文 | Siying Xiang;Zhao Jing;Lu Ying;Ru-Meng Chen;Yan Wang;Yi Chen;Long Bin;Liping Zhu;Yao Peifen;Yifeng Xu;Jianhua Chen |
| 18 | 中药防治抗精神病药物所致代谢功能异常的研究进展 | 期刊论文 | 罗超;涂斯婧;赵苇苇;李宁宁;鞠培俊;徐一峰;陈剑华 |
| 19 | 抗精神病药物相关代谢综合征的易感基因及其应用 | 专利 | 陈剑华;徐一峰;师咏勇;杨琳;李岩;王琰;梁世桥 |
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