受非编码区易感位点调控的新型CASP8剪接异构体促进食管癌癌变机制研究

81872033
2018
H1812.肿瘤预防
赵晓航
面上项目
研究员
中国医学科学院肿瘤医院
60万元
剪接异构体;深内含子区变异/突变;选择性剪接;食管肿瘤;遗传变异
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 线粒体磷酸烯醇式丙酮酸羧激酶与肿瘤 期刊论文 孙艳;赵晓航
2 Mutant p53 increases exosome-mediated transfer of miR-21-3p and miR-769-3p to promote pulmonary metastasis 期刊论文 Ju Qiang;Zhao Lina;Gao Jiajia;Zhou Lanping;Xu Yang;Sun Yulin;Zhao Xiaohang
3 Acetylation-induced PCK isoenzyme transition promotes metabolic adaption of liver cancer to systemic therapy 期刊论文 Jing Zongpan;Gao Jiajia;Li Jun;Niu Fangfei;Tian Lusong;Nan Peng;Sun Yan;Xie Xiufeng;Zhu Ying;Zhao Yan;Liu Fang;Zhou Lanping;Sun Yulin;Zhao Xiaohang
4 Integrated proteomics revealed metabolism reprogramming involved in sorafenib resistant liver cancer cells 会议论文 Zongpan Jing;Fangfei Niu;Yan Sun;Yulin Sun;Xiaohang Zhao
5 Integrated analysis of circulating tumour cells and circulating tumour DNA to detect minimal residual disease in hepatocellular carcinoma 期刊论文 Lina Zhao;Liping Jiang;Yunhe Liu;Xuebing Wang;Jinge Song;Yulin Sun;Yinlei Bai;Xiu Dong;Li-Ying Sun;Jianxiong Wu;Yuchen Jiao;Xiaohang Zhao
6 BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial-mesenchymal transition and angiogenesis 期刊论文 Zhao Yan;Gao Jiajia;Xie Xiufeng;Nan Peng;Liu Fang;Sun Yulin;Zhao Xiaohang
7 Spatial heterogeneity in epithelial to mesenchymal transition properties of circulating tumor cells associated with distant recurrence in pancreatic cancer patients 期刊论文 Xiu Dong;Yongsu Ma;Xudong Zhao;Xiaodong Tian;Yulin Sun;Yinmo Yang;Xiaohang Zhao
8 可变多聚腺苷酸化与肿瘤 期刊论文 田路松;赵晓航
9 BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids 期刊论文 Xiufeng Xie;Lusong Tian;Yan Zhao;Fang Liu;Shuyang Dai;Xinglu Gu;Yuxin Ye;Lanping Zhou;Xinmiao Liu;Yulin Sun;Xiaohang Zhao
10 转录因子BACH1与人类肿瘤 期刊论文 解修峰;孙艳;赵晓航
11 Integrated proteomics revealed metabolism reprogramming involved in sorafenib resistant liver cancer cells 会议论文 Zongpan Jing;Yan Sun;Yulin Sun;Xiaohang Zhao
12 室温放置4 h对样本尿蛋白质组分析的影响 期刊论文 杨丽君;郭正光;景宗攀;孙玉琳;孙伟;赵晓航
13 抗Stathmin单克隆抗体及其用途 专利 赵晓航;孙玉琳;颜露;刘芳;周兰萍;许杨;韩改净;牛芳斐
14 Integrated proteomics revealed acetylation-induced PCK isoenzyme transition promotes metabolic adaptation of liver cancer to systemic therapy 会议论文 Zongpan Jing;Lusong Tian L;Peng Nan;Xiufeng Xie;Ying Zhu;Xinglu Gu;Yulin Sun;Xiaohang Zhao
15 Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin αvβ3/CD36-mediated activation of the MAPK pathway 期刊论文 Peng Nan;Xiu Dong;Xiaofeng Bai;Haizhen Lu;Fang Liu;Yulin Sun;Xiaohang Zhao
16 肝细胞癌尿代谢组学初步研究 期刊论文 解修峰;孙艳;赵晓航
17 PURα mediates epithelial–mesenchymal transition to promote esophageal squamous cell carcinoma metastasis via modulation of Wnt/β-catenin signaling 会议论文 Jiajia Gao;Lusong Tian;Lanping Zhou;Fang Liu;Yulin Sun;Xiaohang Zhao
18 A urinary metabolomics study of colorectal cancer diagnosis and metastasis markers 会议论文 Jun Li;Xiaoyan Liu;Yan Sun;Jing Li;Yan Zhao;Yan Zhao;Xiang Liu;Yulin Sun;Zhengguang Guo;Wei Sun;Xiaohang Zhao
19 MARCKSL1 interacted with F-actin to promote esophageal squamous cell carcinoma mobility by modulating the formation of invadopodia 期刊论文 Yue Zhao;Xiufeng Xie;Lusong Tian;Fang Liu;Yulin Sun;Haizhen Lu;Xiaohang Zhao;Yousheng Mao
20 Urinary proteins RAD23B and CORO1C associated with colorectal cancer progression and metastasis 会议论文 Yulin Sun;Zhengguang Guo;XiaoyanLiu X;Lijun Yang;Jun Li;Lusong Tian;Peng Nan;Xiufeng Xie;Wei Sun;Xiaohang Zhao
21 Noninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis 期刊论文 Yulin Sun;Zhengguang Guo;Xiaoyan Liu;Lijun Yang;Zongpan Jing;Meng Cai;Zhaoxu Zheng;Chen Shao;Yefan Zhang;Haidan Sun;Li Wang;Minjie Wang;Jun Li;Lusong Tian;Yue Han;Shuangmei Zou;Jiajia Gao;Yan Zhao;Peng Nan;Xiufeng Xie;Fang Liu;Lanping Zhou;Wei Sun;Xiaohang Zhao
22 TMT-based isobaric labeling quantitative proteomics reveals distinctive protein expression profile and potential biomarker in pancreatic cancer 会议论文 Xiu Dong;Lanping Zhou;Fang Liu;Yulin Sun;Jianqiang Cai;Xiaohang Zhao
23 Screening of colorectal cancer diagnosis and metastasis markers by urinary metabolomics study 会议论文 Jun Li;Xiaoyan Liu;Yulin Sun;Zhengguang Guo;Lijun Yang;Jing Li;Yan Sun;Xiang Liu;Wei Sun;Xiaohang Zhao
24 PURα Promotes the Transcriptional Activation of PCK2 in Oesophageal Squamous Cell Carcinoma Cells 期刊论文 Yan Sun;Jiajia Gao;Zongpan Jing;Yan Zhao;Yunlin Sun;Xiaohang Zhao
25 Serum autoantibody as biomarkers for early lymph node metastasis in patients with esophageal squamous cell carcinoma 会议论文 Yan Zhao;ShuYang Dai;YuLin Sun;LanPing Zhou;Yan Sun;XiaoHang Zhao
26 Forming cytoplasmic stress granules PURα suppresses mRNA translation initiation of IGFBP3 to promote esophageal squamous cell carcinoma progression 期刊论文 Lusong Tian;Xiufeng Xie;Urmi Das;Yuling Chen;Yulin Sun;Fang Liu;Haizhen Lu;Peng Nan;Ying Zhu;Xinglu Gu;Haiteng Deng;Jiuyong Xie;Xiaohang Zhao
27 PURα mediates epithelial-mesenchymal transition to promote esophageal squamous cell carcinoma progression by regulating Snail2 期刊论文 Jiajia Gao;Lusong Tian;Yulin Sun;Wei Li;Lina Zhao;Yan Sun;Zongpan Jing;Lanping Zhou;Fang Liu;Xiaohang Zhao
28 Integrated capacity of CTCs and ctDNA for dynamically monitoring and prognostication from hepatocellular carcinoma patients undergoing surgery treatment 会议论文 Lina zhao;Jinge Song;Yunhe Liu;Xiu dong;Yulin Sun;Jianxiong Wu;Yuchen Jiao;Xiaohang Zhao
29 Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis 期刊论文 Li Jun;Tian Lusong;Jing Zongpan;Guo Zhengguang;Nan Peng;Liu Fang;Zou Shuangmei;Yang Lijun;Xie Xiufeng;Zhu Ying;Zhao Yue;Sun Wei;Sun Yulin;Zhao Xiaohang
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