克拉酸生物合成过程机制解析与代谢调控研究

31870069
2018
C0104.微生物遗传与生物合成
堵国成
面上项目
教授
江南大学
62万元
转录调控;动态调控;系统生物学;反义转录;克拉酸
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Engineered Bacillus subtilis for the de novo production of 2'-fucosyllactose 期刊论文 Quanwei Zhang;Zhenmin Liu;Hongzhi Xia;Ziyang Huang;Yonglian Zhu;Linfeng Xu;Yanfeng Liu;Jianghua Li;Guocheng Du;Xueqin Lv;Long Liu
2 Engineering a bifunctional Phr60-Rap60-Spo0A quorum-sensing molecular switch for dynamic fine-tuning of menaquinone-7 synthesis in Bacillus subtilis 期刊论文 Shixiu Cui;Xueqin Lv;Yaokang Wu;Jianghua Li;Guocheng Du;Rodrigo Ledesma-Amaro;Long Liu
3 Combinatorial metabolic engineering and enzymatic catalysis enable efficient production of colanic acid 期刊论文 Suwei Li;Xianhao Xu;Xueqin Lv;Yanfeng Liu;Jianghua Li;Guocheng D;Long Liu
4 Model-based dynamic engineering of Escherichia coli for N-acetylglucosamine overproduction 期刊论文 Jiangong Lu;Yaokang Wu;Chen Deng;Yanfeng Liu;Xueqin Lv;Jianghua Li;Guocheng Du;Long Liu
5 Engineering the substrate transport and cofactor regeneration systems for enhancing 2'-Fucosyllactose synthesis in Bacillus subtilis 期刊论文 Jieying Deng;Liuyan Gu;Taichi Chen;Hao Huang;Xiaoqiang Yin;Xueqin Lv;Yanfeng Liu;Nan Li;Zhenmin Liu;Jianghua Li;Guocheng Du;Long Liu
6 Pyruvate-responsive genetic circuits for dynamic control of central metabolism 期刊论文 Xianhao Xu;Xueliang Li;Yanfeng Liu;Yonglian Zhu;Jianghua Li;Guocheng Du;Jian Chen;Rodrigo Ledesma-Amaro;Long Liu
7 Semi-rational design of L-amino acid deaminase for production of pyruvate and D-alanine by Escherichia coli whole-cell biocatalyst 期刊论文 Ke Liu;Haoran Yu;Guoyun Sun;Yanfeng Liu;Jianghua Li;Guocheng Du;Xueqin Lv;Long Liu
8 Combinatorial metabolic engineering of Escherichia coli for de novo production of 2'-fucosyllactose 期刊论文 Lu Lin;Mengyue Gong;Yanfeng Liu;Jianghua Li;Xueqin Lv;Guocheng Du;Long Liu
9 Transgenic strain containing an isolated promoter 专利 Long Liu;Jian Chen;Guocheng Du;Xian Yin;Jianghua Li
10 功能营养品的细胞工厂构建及应用技术 奖励 刘龙;陈坚;吕雪芹;刘延峰;堵国成;刘松;张国强;李江华;黄子洋;卢健行;卢伟;张弘治;夏洪志
11 Recent advances and challenges in microbial production of human milk oligosaccharides 期刊论文 Jieying Deng;Xueqin Lv;Jianghua Li;Guocheng Du;Jian Chen;Long Liu
12 丙酮酸响应生物传感器及其构建方法与应用 专利 刘龙;陈坚;堵国成;李江华;徐显皓
13 A genetic toolkit for efficient production of secretory protein in Bacillus subtilis 期刊论文 Yang Li;Yaokang Wu;Yanfeng Liu;Jianghua Li;Guocheng Du;Xueqin Lv;Long Liu
14 Metabolic engineering for the production of fat-soluble vitamins: advances and perspectives 期刊论文 Panhong Yuan;Shixiu Cui;Yanfeng Liu;Jianghua Li;Guocheng Du;Long Liu
15 Combinatorial engineering for improved menaquinone-4 biosynthesis in Bacillus subtilis 期刊论文 Panhong Yuan;Shixiu Cui;Yanfeng Liu;Jianghua Li;Xueqin Lv;Long Liu;Guocheng Du
16 Combinatorial methylerythritol phosphate pathway engineering and process optimization for increased menaquinone-7 synthesis in Bacillus subtilis 期刊论文 Taichi Chen;Hongzhi Xia;Shixiu Cui;Xueqin Lv;Xueliang Li;Yanfeng Liu;Jianghua Li;Guocheng Du;Long Liu
17 一种微液滴生物传感器的构建方法及其应用 专利 刘龙;陈坚;吕雪芹;堵国成;李江华;刘延锋;孙国运
18 高效合成丙酮酸与D-丙氨酸的工程菌及其构建方法与应用 专利 刘龙;陈坚;堵国成;李江华;吕雪芹;刘克;周璇;曲丽莎
19 合成丙酮酸与D-丙氨酸额基因工程菌及其构建方法与应用 专利 刘龙;刘克;毛馨竹;曲丽莎;堵国成;李江华;陈坚
20 Design and construction of novel biocatalyst for bioprocessing: Recent advances and future outlook 期刊论文 Yameng Xu;Yaokang Wu;Xueqin Lv;Guoyun Sun;Hongzhi Zhang;Taichi Chen;Guocheng Du;Jianghua Li;Long Liu
21 Biocatalytic synthesis of lactosucrose using a recombinant thermostable β-fructofuranosidase from Arthrobacter sp. 10138 期刊论文 Chunmei Chen;Jieying Deng;Xueqin Lv;Jianghua Li;Guocheng Du;Huazhong Li;Long Liu
22 Combining CRISPR-Cpf1 and recombineering facilitates fast and efficient genome editing in Escherichia coli 期刊论文 Xuewen Zhu;Yaokang Wu;Xueqin Lv;Yanfeng Liu;Guocheng Du;Jianghua Li;Long Liu
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