基于“适配体捕获-磁分选”评价体系的中药抗肿瘤活性成分纳米脂质体的药动学研究

81773988
2017
H3216.中药代谢与药物动力学
陈卫东
面上项目
教授
安徽中医药大学
50万元
适配体;中药抗肿瘤活性成分;药代动力学;功能化磁珠;纳米脂质体
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Acidity and Glutathione Dual-Responsive Polydopamine-Coated Organic-Inorganic Hybrid Hollow Mesoporous Silica Nanoparticles for Controlled Drug Delivery. 期刊论文 Weidong Chen;Qi Chen;Yunna Chen;Wenjing Zhang;Qianqian Huang;Mengru Hu;Daiyin Peng;Can Peng;Lei Wang
2 Exosomes from M1-Polarized Macrophages Enhance Paclitaxel Antitumor Activity by Activating Macrophages-Mediated Inflammation. 期刊论文 Piaopiao Wang;Huihui Wang;Qianqian Huang;Can Peng;Liang Yao;Hong Chen;Zhen Qiu;Yifan Wu;Lei Wang;Weidong Chen
3 Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo 期刊论文 Fengling Wang;Yifan Wu;Jiwen Zhang;Huihui Wang;Xiaoting Xie;Xi Ye;Daiyin Peng;Weidong Chen
4 Essential role of nuclear receptors for the evaluation of the benefits of bioactive herbal extracts on liver function. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 期刊论文 Fengling Wang;Yifan Wu;Xiaoting Xi;Jing Sun;Weidong Chen
5 Co-delivery of gambogenic acid and VEGF-siRNA with anionic liposome and polyethylenimine complexes to HepG2 cells 期刊论文 Qiongfang Yu;Bian Zhang;Yali Zhou;Qin Ge;Jiali Chang;Yunna Chen;Kaiqi Zhang;Daiyin Peng;Weidong Chen
6 Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo 期刊论文 Fengling Wang;Huihui Wang;Yifan Wu;Lei Wang;Ling Zhang;Xi Ye;Daiyin Peng;Weidong Chen
7 A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes 期刊论文 Yunna Chen;Lei Wang;Dongdong Guo;Chenming Sheng;Haozhi Dai;Xiaoyan Shi;Wenjing Zhang;Qianqian Huang;Can Peng;Weidong Chen
8 PEGylated liposomes as delivery systems for Gambogenic acid: Characterization and in vitro/in vivo evaluation 期刊论文 Xiaozhu Tang;Jing Sun;Tao Ge;Kaiqi Zhang;Qiuyi Gui;Shantang Zhang;Weidong Chen
9 Amphiphilic Block Copolymer Poly (Acrylic Acid)-B-Polycaprolactone as a Novel pH-sensitive Nanocarrier for Anti-Cancer Drugs Delivery: In-vitro and In-vivo Evaluation. 期刊论文 Huanhuan Liu;Hong Chen;Fuhu Cao;Daiyin Peng;Weidong Chen;Chuanling Zhang
10 Time Interval of Two Injections and First-Dose Dependent of Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomal Gambogenic Acid: The Contribution of PEG-Specific IgM 期刊论文 Fengling Wang;Xi Ye;Yifan Wu;Huihui Wang;Chengming Sheng;Daiyin Peng;Weidong Chen
11 Folic acid-modified nonionic surfactant vesicles for gambogenic acid targeting: Preparation, characterization, and in vitro and in vivo evaluation. 期刊论文 Tong-Yuan Lin;Jia-Li Chang;Yan Xun;Yi Zhao;Wang Pen;Wang Yang;Bai-Jing Ding;Wei-Dong Chen
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