聚乙二醇修饰血红蛋白四聚体的稳定性研究

20906095
2009
B0810.农业与食品化工
胡涛
青年科学基金项目
研究员
中国科学院过程工程研究所
20万元
聚乙二醇;四聚体稳定性;血红蛋白;血液代用品;化学修饰
2010-01-01到2012-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Preparation, structural analysis and bioactivity of ribonuclease A-albumin conjugate: tetra-conjugation or PEG as the linker 期刊论文 Li Chunju|Lin Qixun|Wang Jun|Ma Guanghui|Su Zhiguo|Hu Tao|
2 Mono-PEGylation of ribonuclease A: High PEGylation efficiency by thiolation with small molecular weight reagent 期刊论文 Liu, Shenxiang|Sun, Lijing|Wang, Jun|Ma, Guanghui|Su, Zhiguo|Hu, Tao|
3 Propylbenzmethylation at Val-1(alpha) markedly increases the tetramer stability of the PEGylated hemoglobin: a comparison with propylation at Val-1(alpha) 期刊论文 Hu Tao|Li Dongxia|Wang Jun|Wang Qingqing|Liang Yangui|Su Yanlei|Ma Guanghui|Su Zhiguo|Wang Shihua|
4 Phenyl linker-induced dense PEG conformation improves the efficacy of C-terminally monoPEGylated staphylokinase 期刊论文 Xue Xiaoying|Li Dongxia|Yu Jingkai|Ma Guanghui|Su Zhiguo|Hu Tao|
5 Preparation, characterization and in vitro bioactivity of N-terminally PEGylated staphylokinase dimers 期刊论文 Liu, Ruyan|Li, Dongxia|Wang, Jun|Qiu, Rui|Lin, Qixun|Zhang, Guifeng|Ma, Guanghui|Su, Zhiguo|Hu, Tao|
6 Kinetic and stoichiometric analysis of the modification process for N-terminal PEGylation of staphylokinase 期刊论文 Wang, Jun|Hu, Tao|Liu, Yongdong|Zhang, Guifeng|Ma, Guanghui|Su, Zhiguo|
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