马齿苋新骨架生物碱抑制脂多糖刺激巨噬细胞NF-κB和MAPK信号通路的抗炎机制及其药动学研究

81573546
2015
H3203.中药药效物质
英锡相
面上项目
教授
辽宁中医药大学
54万元
药动学;新骨架生物碱;小鼠单核巨噬细胞白血病细胞;马齿苋;抗炎机制
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Cytotoxicity of hydroxydihydrobovolide and its pharmacokinetic studies in Portulaca oleracea L. extract 期刊论文 Liang Xu;Xiaojun Tao;Yucong Gao;Wenjie Zhang;Yihan Meng;Cuiyu Li;Mingyue Jiang;Xixiang Ying
2 Pharmacokinetic studies of soyalkaloid A from Portulaca oleracea L. using ultra high-performance liquid chromatography electrospray ionization quadrupole-time of flight mass spectrometry and its antioxidant activity 期刊论文 Fen Xiu;Zheming Ying;Xixiang Ying;Guanli Yang
3 马齿苋中生物碱Oleracone及其提取分离方法 专利 英锡相;张文洁;孟一晗;英哲铭
4 New flavonoids from Portulaca oleracea L. and their activities. 期刊论文 Xu Yang;Wenjie Zhang;Xixiang Ying;Didier Stien
5 两种马齿苋来源生物碱作为制备抗炎药物的应用 专利 英锡相;张文洁;孟一晗;英哲铭
6 An isoindole alkaloid from Portulaca oleracea L. 期刊论文 Mingyue Jiang;Wenjie Zhang;Xu Yang;Fen Xiu;Haoran Xu;Xixiang Ying;Didier Stien
7 马齿苋中甘菊蓝结构化合物及其提取分离方法 专利 英锡相;英哲铭;李翠玉;张文洁
8 A new alkaloid from Portulaca oleracea L. and its antiacetylcholinesterase activity 期刊论文 Fen Xiu;Xuetao Li;Wenjie Zhang;Fan He;Xixiang Ying;Didier Stien
9 Two amide glycosides from Portulaca oleracea L. and its bioactivities 期刊论文 Xilong Liu;Haibo Wu;Xiaojun Tao;Xixiang Ying;Didier Stien
10 Three novel alkaloids from Portulaca oleracea L. and their antiinflammatory effects 奖励 英锡相;李翠玉;孟一晗;英哲铭
11 马齿苋的本草考证 会议论文 赵程程;英哲铭;马懿飞;英锡相
12 A new hemoisoflavone from Portulaca oleracea L. and its antioxidant activity 期刊论文 Xu Yang;Zheming Ying;Hairong Liu;Xixiang Ying;Guanli Yang
13 Pharmacokinetics of oleracimine in rats by ultra-high-performance liquid chromatography 期刊论文 Gonglin Qu;Liang Xu;Wenjie Zhang;Xixiang Ying
14 A new indole alkaloid from Portulaca oleracea L. and its antiacetylcholinesterase activity 期刊论文 Wen Xu;Fangxuan Liu;Haibo Wang;Wenjie Zhang;Fan He;Xixiang Ying
15 Two new similar alkaloids from Portulaca oleracea L. 期刊论文 Cuiyu Li;Zheming Ying;Mingzhe Gao;Wenjuan Wei;Dong Hao;Xiaojun Tiao;Liang Xu;Wenjie Zhang;Xixiang Ying;Jing Liu
16 马齿苋中羟基二氢博呋内酯及其提取分离方法 专利 英锡相;张文洁;英哲铭;徐靓;杨旭
17 A pharmacokinetic study on oleracone C after oral and intravenous administration 期刊论文 Xu Yang;Zheming Ying;Fan He;Xixiang Ying;Guanlin Yang
18 Correction to three novel alkaloids from Portulaca oleracea L. and their antiinflammatory effects 期刊论文 Cuiyu Li;Yihan Meng;Zheming Ying;Nan Xu;Dong Hao;Mingzhe Gao;Wenjie Zhang;Liang Xu;Yucong Gao;Didier Stien;Xixiang Ying
19 Two new natural products from Portulaca oleracea L. and their antioxidant and antiacetylcholinesterase activities 期刊论文 Haoran Xu;Wenjie Zhang;Aijing Leng;Xixiang Ying
20 马齿苋中酰胺类生物碱化合物及其提取分离方法 专利 英锡相;英哲铭;徐靓;张文洁;张朝绅
21 Hepatic, gastric and intestina first-pass effects of vitexin-2′′-O-rhamnoside in rats by ultra-high-performance liquid chromatography 期刊论文 Yucong Gao;Yang Du;Zheming Ying;Aijing Leng;Wenjie Zhang;Yihan Meng;Cuiyu Li;Liang Xu;Xixiang Ying;Tingguo Kang
22 Three novel alkaloids from Portulaca oleracea L. and their antiinflammatory effects. Journal of Agricultural and Food Chemistry 奖励 Cuiyu Li;Yihan Meng;Zheming Ying;Nan Xu;Dong Hao;Mingzhe Gao;Wenjie Zhang;Liang Xu;Yucong Gao;Xixiang Ying
23 Tissue distribution and excretion of the five components of Portulaca oleracea L. extract in rat assessed by UHPLC 期刊论文 Wenjie Zhang;Di Li;Aijing Leng;Junjun Ai;Yang Du;Yihan Meng;Yucong Gao;Xixiang Ying
24 Pharmacokinetics of Hesperidin and its Hepatic, Gastric and Intestinal First-pass Effects in Rats 期刊论文 Yingying Gu;Xue Zhang;Ming Xie;Xiaojun Tao;Wenjie Zhang;Chungang Zhang;Xixiang Ying
25 Pharmacokinetics and metabolism of olerciamide A from Portulaca oleracea L. in rats by UHPLC-UV and UHPLC-ESI-Q-TOF/MS. 期刊论文 Zheming Ying;Cuiyu Li;Mingzhe Gao;Xixiang Ying;Guanlin Yang
26 马齿苋水提物中生物碱成分β-咔啉分离鉴定 期刊论文 李翠玉;徐靓;英锡相
27 Two new alkaloids from Portulaca oleracea L. and their bioactivities 期刊论文 Chengcheng Zhao;Chungang Zhang;Fan He;Wenjie Zhang;Aijing Leng;Xixiang Ying
28 马齿苋的基源考证 会议论文 英哲铭;马懿飞;赵程程;英锡相
29 The anti-inflammation and pharmacokinetics of a novel alkaloid from Portulaca oleracea L. Journal of Pharmacy and Pharmacology 奖励 英锡相;孟一晗;英哲铭;项峥
30 Three novel alkaloids from Portulaca oleracea L. and their antiinflammatory effects 期刊论文 Cuiyu Li;Yihan Meng;Zheming Ying;Nan Xu;Dong Hao;Mingzhe Gao;Wenjie Zhang;Liang Xu;Yucong Gao;Xixiang Ying
31 A novel alkaloid from Portulaca oleracea L. 期刊论文 Liang Xu;Zheming Ying;Wenjuan Wei;Dong Hao;Haibo Wang;Wenjie Zhang;Cuiyu Li;Mingyue Jiang;Xixiang Ying;Jing Liu
32 Four lignans from Portulaca oleracea L. and its antioxidant activities 期刊论文 Yifei Ma;Yongrui Bao;Wenjie Zhang;Xixiang Ying;Didier Stien
33 马齿苋中化合物 Oleracone D 及其提取分离方法 专利 英锡相;顾宇;杨旭;英哲铭;张文洁
34 马齿苋提取物在大鼠体内组织分布研究 期刊论文 孟一晗;张文洁;李镝;英锡相
35 马齿苋醇提物中羟基二氢博伏内酯的分离及结构鉴定 期刊论文 徐靓;英锡相
36 马齿苋中两种生物碱化合物及其提取分离方法 专利 英锡相;英哲铭;李翠玉;张文洁;张朝绅
37 The anti-inflammation and pharmacokinetics of a novel alkaloid from Portulaca oleracea L. 期刊论文 Yihan Meng;Zheming Ying;Zheng Xiang;Dong Hao;Wenjie Zhang;Yu Zheng;Yucong Gao;Xixiang Ying
38 马齿苋中化合物Oleracone F及其提取分离方法 专利 英锡相;杨旭;修芬;徐浩然;英哲铭
39 A trace alkaloid, oleraisoindole A from Portulaca oleracea L. and its anticholinesterase effect 期刊论文 Yifei Ma;Xuetao Li;Wenjie Zhang;Xixiang Ying;Didier Stien
40 Investigating the bioavailabilities of olerciamide A via the rat’s hepatic, gastric and intestinal first-pass effect models. 期刊论文 Chengcheng Zhao;Zheming Ying;Dong Hao;Wenjie Zhang;Xixiang Ying;Guanlin Yang
41 马齿苋中骨架生物碱化合物及其提取分离方法 专利 英锡相;英哲铭;张文洁;李翠玉
42 A new lactam alkaloid from Portulaca oleracea L. and its cytotoxity 期刊论文 Chengcheng Zhao;Zheming Ying;Xiaojun Tao;Mingyue Jiang;Xixiang Ying;Guanlin Yang
43 马齿苋中两种酪胺类生物碱分离及鉴定 期刊论文 蒋明月;英锡相
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