活体分析的表界面化学基础研究

21435007
2014
B0404.化学与生物传感
毛兰群
重点项目
教授
中国科学院化学研究所
350万元
活体在线;表界面化学;活体分析;活体原位;微透析
2015-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 活体层次定量获取化学信号的新原理和新方法研究 奖励 毛兰群;于萍;张美宁;严乙铭;林雨青
2 Monitoring gamma-glutamyl transpeptidase activity and evaluating its inhibitors by a water-soluble near-infrared fluorescent probe 期刊论文 Li Lihong;Shi Wen;Wu Xiaofeng;Gong Qiuyu;Li Xiaohua;Ma Huimin
3 In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe 期刊论文 He Xinyuan;Li Lihong;Fang Yu;Shi Wen;Li Xiaohua;Ma Huimin
4 Facile and Sensitive Method for Protein Kinase A Activity Assay Based on Fluorescent Off-On PolyU-peptide Assembly 期刊论文 Xu Yanhui;Shi Wen;He Xinyuan;Wu Xiaofeng;Li Xiaohua;Ma Huimin
5 Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles 期刊论文 Liu Ji;Chang Jin;Jiang Ying;Meng Xiandi;Sun Tianmeng;Mao Lanqun;Xu Qiaobing;Wang Ming
6 万人计划——科技创新领军人才 奖励 毛兰群
7 Design, synthesis and application of a near-infrared fluorescent probe for in vivo imaging of aminopeptidase N 期刊论文 He Xinyuan;Hu Yiming;Shi Wen;Li Xiaohua;Ma Huimin
8 HOCl can appear in the mitochondria of macrophages during bacterial infection as revealed by a sensitive mitochondrial-targeting fluorescent probe 期刊论文 Zhou Jin;Li Lihong;Shi Wen;Gao Xinghui;Li Xiaohua;Ma Huimin
9 活体检测H2S的电极、制备方法和活体检测H2S的装置 专利 毛兰群;林振宇;陈仲辉
10 Sensitive and Selective Ratiometric Fluorescence Probes for Detection of Intracellular Endogenous Monoamine Oxidase A 期刊论文 Wu Xiaofeng;Li Lihong;Shi Wen;Gong Qiuyu;Li Xiaohua;Ma Huimin
11 Rationally Designed Fluorescence (OH)-O-center dot Probe with High Sensitivity and Selectivity for Monitoring the Generation of (OH)-O-center dot in Iron Autoxidation without Addition of H2O2 期刊论文 Li Hongyu;Li Xiaohua;Shi Wen;Xu Yanhui;Ma Huimin
12 Nonlinear dependence of the ion current rectification factor on bias voltage in conical nanopipettes 期刊论文 Li Ting;He Xiulan;Yu Ping;Mao Lanqun
13 百千万人才工程——有突出贡献中青年专家 奖励 毛兰群
14 In Vivo Measurement of Calcium Ion with Solid-State Ion-Selective Electrode by Using Shelled Hollow Carbon Nanospheres as a Transducing Layer 期刊论文 Zhao Lijun;Jiang Ying;Wei Huan;Jiang Yanan;Ma Wenjie;Zheng Wei;Cao An Min;Mao Lanqun
15 Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing 期刊论文 Yang Xiaoti;Tang Qiao;Jiang Ying;Zhang Meining;Wang Ming;Mao Lanqun
16 A Strategy for Specific Fluorescence Imaging of Monoamine OxidaseA in Living Cells 期刊论文 Wu Xiaofeng;Shi Wen;Li Xiaohua;Ma Huimin
17 超分子离子材料及其制备方法及在制备湿度传感器件中的用途 专利 毛兰群;于萍;颜海龙
18 Leucine aminopeptidase may contribute to the intrinsic resistance of cancer cells toward cisplatin as revealed by an ultrasensitive fluorescent probe 期刊论文 Gong Qiuyu;Shi Wen;Li Lihong;Ma Huimin
19 中国化学会分析化学基础研究梁树权奖 奖励 毛兰群
20 Biological Applications of Organic Electrochemical Transistors: Electrochemical Biosensors and Electrophysiology Recording 期刊论文 Bai Liming;Elosegui Cristina Garcia;Li Weiqi;Yu Ping;Fei Junjie;Mao Lanqun
21 A single-atom Fe-N-4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection 期刊论文 Ma Wenjie;Mao Junjie;Yang Xiaoti;Pan Cong;Chen Wenxing;Wang Ming;Yu Ping;Mao Lanqun;Li Yadong
22 Reactive oxygen species-triggered off-on fluorescence donor for imaging hydrogen sulfide delivery in living cells. 期刊论文 Hu Yiming;Li Xiaoyi;Fang Yu;Shi Wen;Li Xiaohua;Chen Wei;Xian Ming;Ma Huimin
23 Online electrochemical system as an in vivo method to study dynamic changes of ascorbate in rat brain during 3-methylindole-induced olfactory dysfunction 期刊论文 Li Lijuan;Zhang Yinghong;Hao Jie;Liu Junxiu;Yu Ping;Ma Furong;Mao Lanqun
24 Tuning Interionic Interaction for Highly Selective In Vivo Analysis 期刊论文 Yu Ping;He Xiulan;Mao Lanqun
25 Ultrasonic-Aided Fabrication of Nanostructured Au-Ring Microelectrodes for Monitoring Transmitters Released from Single Cells 期刊论文 Wang Keqing;Zhao Xu;Li Bo;Wang Kai;Zhang Xin;Mao Lanqun;Ewing Andrew;Lin Yuqing
26 Chaotropic Monovalent Anion-Induced Rectification Inversion at Nanopipettes Modified by Polyimidazolium Brushes 期刊论文 He Xiulan;Zhang Kailin;Liu Yang;Wu Fei;Yu Ping;Mao Lanqun
27 Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing 期刊论文 Chang Jin;Chen Xianghan;Glass Zachary;Gao Feng;Mao Lanqun;Wang Ming;Xu Qiaobing
28 Recognition Moieties of Small Molecular Fluorescent Probes for Bioimaging of Enzymes. 期刊论文 Wu Xiaofeng;Shi Wen;Li Xiaohua;Ma Huimin
29 Counting and Sizing of Single Vesicles/Liposomes by Electrochemical Events 期刊论文 Liu Yang;Xu Cong;Yu Ping;Chen Xuwei;Wang Jianhua;Mao Lanqun
30 Voltage-driven counting of phospholipid vesicles with nanopipettes by resistive-pulse principle 期刊论文 Liu Yang;Xu Cong;Chen Xuwei;Wang Jianhua;Yu Ping;Mao Lanqun
31 活体检测电极校正方法及其应用 专利 毛兰群;张美宁;刘孝猛
32 Near-Infrared Fluorescent Probe with New Recognition Moiety for Specific Detection of Tyrosinase Activity: Design, Synthesis, and Application in Living Cells and Zebrafish 期刊论文 Wu Xiaofeng;Li Lihong;Shi Wen;Gong Qiuyu;Ma Huimin
33 Detection of Misdistribution of Tyrosinase from Melanosomes to Lysosomes and Its Upregulation under Psoralen/Ultraviolet A with a Melanosome-Targeting Tyrosinase Fluorescent Probe 期刊论文 Zhou Jin;Shi Wen;Li Lihong;Gong Qiu-Yu;Wu Xiaofeng;Li Xiaohua;Ma Huimin
34 Ferroptosis Accompanied by ()OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe. 期刊论文 Li Hongyu;Shi Wen;Li Xiaohua;Hu Yiming;Fang Yu;Ma Huimin
35 Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells 期刊论文 Gong Qiuyu;Shi Wen;Li Lihong;Wu Xiaofeng;Ma Huimin
36 Ultrasensitive Detection of Aminopeptidase N Activity in Urine and Cells with a Ratiometric Fluorescence Probe 期刊论文 He Xinyuan;Xu Yanhui;Shi Wen;Ma Huimin
37 Ion current rectification: from nanoscale to microscale 期刊论文 Xiong Tianyi;Zhang Kailin;Jiang Yanan;Yu Ping;Mao Lanqun
38 Carbon Atom Hybridization Matters: Ultrafast Humidity Response of Graphdiyne Oxides 期刊论文 Yan Hailong;Guo Shuyue;Wu Fei;Yu Ping;Liu Huibiao;Li Yuliang;Mao Lanqun
39 A dual-function fluorescent probe for monitoring the degrees of hypoxia in living cells via the imaging of nitroreductase and adenosine triphosphate 期刊论文 Fang Yu;Shi. Wen;Hu Yiming;Li Xiaohua;Ma Huimin
40 检测单颗粒的方法和装置 专利 毛兰群;于萍;李婷
41 A near-infrared fluorescence off-on probe for sensitive imaging of hydrogen polysulfides in living cells and mice in vivo 期刊论文 Fang Yu;Chen Wei;Shi Wen;Li Hongyu;Xian Ming;Ma Huimin
42 测定多巴胺的方法 专利 于萍;李玮琦;毛兰群
43 pH传感器、制备方法以及用途 专利 毛兰群;于萍;郝洁
44 Comparison of N-acetylcysteine and cysteine in their ability to replenish intracellular cysteine by a specific fluorescent probe 期刊论文 He Xinyuan;Wu Xiaofeng;Shi Wen;Ma Huimin
45 一种微型pH传感器的制备方法与应用 专利 毛兰群;张凯林;于萍
46 Sensitive Fluorescence Probe with Long Analytical Wavelengths for gamma-Glutamyl Transpeptidase Detection in Human Serum and Living Cells 期刊论文 Li Lihong;Shi Wen;Wang Zhe;Gong Qiuyu;Ma Huimin
47 Ratiometric Fluorescent Probe for Imaging of Pantetheinase in Living Cells 期刊论文 Hu Yiming;Li Hongyu;Shi Wen;Ma Huimin
48 Ferricyanide-backfilled cylindrical carbon fiber microelectrodes for in vivo analysis with high stability and low polarized potential. 期刊论文 Zhong Peipei;Yu Ping;Wang Kai;Hao Jie;Fei Junjie;Mao Lanqun
49 Graphdiyne-Promoted Highly Efficient Photocatalytic Activity of Graphdiyne/Silver Phosphate Pickering Emulsion Under Visible-Light Irradiation 期刊论文 Guo Shuyue;Jiang Yanan;Wu Fei;Yu Ping;Liu Huibiao;Li Yuliang;Mao Lanqun
50 Water Adsorption and Transport on Oxidized Two-Dimensional Carbon Materials 期刊论文 Yan Hailong;Wu Fei;Xue Yifei;Bryan Kevin;Ma Wenjie;Yu Ping;Mao Lanqun
51 In vivo tumor imaging by a gamma-glutamyl transpeptidase-activatable near-infrared fluorescent probe 期刊论文 Li Lihong;Shi Wen;Wu Xiaofeng;Li Xiaohua;Ma Huimin
52 An Upconversion Luminescence Nanoprobe for the Ultrasensitive Detection of Hyaluronidase 期刊论文 Wang Zhe;Li Xiaohua;Song Yanchao;Li Lihong;Shi Wen;Ma Huimin
53 A Lysosome-Targeting Fluorescence Off-On Probe for Imaging of Nitroreductase and Hypoxia in Live Cells 期刊论文 Zhou Jin;Shi Wen;Li Li-Hong;Gong Qiu-Yu;Wu Xiao-Feng;Li Xiao-Hua;Ma Hui-Min
54 Galvanic Redox Potentiometry for Self-Driven in Vivo Measurement of Neurochemical Dynamics at Open-Circuit Potential 期刊论文 Wu Fei;Cheng Hanjun;Wei Huan;Xiong Tianyi;Yu Ping;Mao Lanqun
55 Simultaneous in vivo ascorbate and electrophysiological recordings in rat brain following ischemia/reperfusion 期刊论文 Cheng Hanjun;Xiao Tongfang;Wang Dalei;Hao Jie;Yu Ping;Mao Lanqun
56 Controllable and Reproducible Sheath of Carbon Fibers with Single-Walled Carbon Nanotubes through Electrophoretic Deposition for In Vivo Electrochemical Measurements 期刊论文 Xiao Tongfang;Jiang Yanan;Ji Wenliang;Mao Lanqun
57 Recent advances on in vivo analysis of ascorbic acid in brain functions 期刊论文 Cheng Hanjun;Li Lijuan;Zhang Meining;Jiang Ying;Yu Ping;Ma Furong;Mao Lanqun
58 High-Yield and Damage-free Exfoliation of Layered Graphdiyne in Aqueous Phase 期刊论文 Yan Hailong;Yu Ping();Han Guangchao;Zhang Qinghua;Gu Lin;Yi Yuanping();Liu Huibiao;Li Yuliang();Mao Lanqun()
59 万人计划——科技创新领军人才 奖励 毛兰群
60 Ultrathin Cell-Membrane-Mimic Phosphorylcholine Polymer Film Coating Enables Large Improvements for InVivo Electrochemical Detection 期刊论文 Liu Xiaomeng;Xiao Tongfang;Wu Fei;Shen Mo Yuan;Zhang Meining();Yu Hsiao hua();Mao Lanqun()
61 Nitrogen-doped carbon nanotubes as an excellent substrate for electroless deposition of Pd nanoparticles with a high efficiency toward the hydrogen evolution reaction 期刊论文 Zhou Siliao;Chen Xianghan;Yu Ping;Gao Feng;Mao Lanqun
62 活体层次定量获取化学信号的新原理和新方法研究 奖励 毛兰群;于萍;张美宁;严乙铭;林雨青
63 A single-atom Fe-N-4 catalytic site mimicking bifunctional antioxidative enzymes for oxidative stress cytoprotection 期刊论文 Ma Wenjie;Mao Junjie;Yang Xiaoti;Pan Cong;Chen Wenxing;Wang Ming;Yu Ping;Mao Lanqun;Li Yadong
64 Neuroprotective effects of MK-801 on auditory cortex in salicylate-induced tinnitus: Involvement of neural activity, glutamate and ascorbate 期刊论文 Xiong Shan;Song Yu;Liu Junxiu;Du Yali;Ding Yujing;Wei Huan;Bryan Kevin;Ma Furong();Mao Lanqun()
65 Comparison of N-acetylcysteine and cysteine in their ability to replenish intracellular cysteine by a specific fluorescent probe 期刊论文 He Xinyuan;Wu Xiaofeng;Shi Wen;Ma Huimin
66 Graphdiyne-Promoted Highly Efficient Photocatalytic Activity of Graphdiyne/Silver Phosphate Pickering Emulsion Under Visible-Light Irradiation 期刊论文 Guo Shuyue;Jiang Yanan;Wu Fei;Yu Ping;Liu Huibiao;Li Yuliang;Mao Lanqun
67 Galvanic Redox Potentiometry for Self-Driven in Vivo Measurement of Neurochemical Dynamics at Open-Circuit Potential 期刊论文 Wu Fei;Cheng Hanjun;Wei Huan;Xiong Tianyi;Yu Ping;Mao Lanqun
68 Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles 期刊论文 Liu Ji;Chang Jin;Jiang Ying;Meng Xiandi;Sun Tianmeng;Mao Lanqun;Xu Qiaobing;Wang Ming
69 A dual-function fluorescent probe for monitoring the degrees of hypoxia in living cells via the imaging of nitroreductase and adenosine triphosphate 期刊论文 Fang Yu;Shi. Wen;Hu Yiming;Li Xiaohua;Ma Huimin
70 In vivo imaging of leucine aminopeptidase activity in drug-induced liver injury and liver cancer via a near-infrared fluorescent probe 期刊论文 He Xinyuan;Li Lihong;Fang Yu;Shi Wen;Li Xiaohua;Ma Huimin
71 In vivo tumor imaging by a gamma-glutamyl transpeptidase-activatable near-infrared fluorescent probe 期刊论文 Li Lihong;Shi Wen;Wu Xiaofeng;Li Xiaohua;Ma Huimin
72 Ferroptosis Accompanied by ()OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe. 期刊论文 Li Hongyu;Shi Wen;Li Xiaohua;Hu Yiming;Fang Yu;Ma Huimin
73 Design, synthesis and application of a near-infrared fluorescent probe for in vivo imaging of aminopeptidase N 期刊论文 He Xinyuan;Hu Yiming;Shi Wen;Li Xiaohua;Ma Huimin
74 Ratiometric Fluorescent Probe for Imaging of Pantetheinase in Living Cells 期刊论文 Hu Yiming;Li Hongyu;Shi Wen;Ma Huimin
75 Rationally Designed Fluorescence (OH)-O-center dot Probe with High Sensitivity and Selectivity for Monitoring the Generation of (OH)-O-center dot in Iron Autoxidation without Addition of H2O2 期刊论文 Li Hongyu;Li Xiaohua;Shi Wen;Xu Yanhui;Ma Huimin
76 Ultrasensitive Detection of Aminopeptidase N Activity in Urine and Cells with a Ratiometric Fluorescence Probe 期刊论文 He Xinyuan;Xu Yanhui;Shi Wen;Ma Huimin
77 Facile and Sensitive Method for Protein Kinase A Activity Assay Based on Fluorescent Off-On PolyU-peptide Assembly 期刊论文 Xu Yanhui;Shi Wen;He Xinyuan;Wu Xiaofeng;Li Xiaohua;Ma Huimin
78 pH传感器、制备方法以及用途 专利 毛兰群;于萍;郝洁
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