【21175138】基于氨基酸离子液体的手性配体交换毛细管电泳技术研究国家自然基金项目

基于氨基酸离子液体的手性配体交换毛细管电泳技术研究

项目批准号： 21175138

批准年份： 2011

学科分类： B0401.分离与分析

项目负责人：齐莉

资助类别：面上项目

负责人职称：研究员

依托单位：中国科学院化学研究所

资助金额： 60万元

关键词：氨基酸离子液体;氨基酸手性分析;酶反应动力学;手性配体交换毛细管电泳

起止时间： 2012-01-01到2015-12-31

中英文摘要
结题摘要
结题报告
项目成果
项目参与人

查看更多信息请先登录或注册

序号	标题	类型	作者
1	Amphiphilic block copolymer modified magnetic nanoparticles for microwave-assisted extraction of polycyclic aromatic hydrocarbons in environmental water	期刊论文	Qi Li\|Shen Ying\|Li Yaping\|Chen Yi\|
2	Microchip CE-LIF method for the hydrolysis of L-glutamine by using L-asparaginase enzyme reactor based on gold nanoparticle	期刊论文	Qi Li\|Yan Huijuan\|Li Yaping\|Mu Xiaoyu\|
3	Preparation of porous polymer monolithic column using functionalized graphene oxide as a functional crosslinker for high performance liquid chromatography separation of small molecules	期刊论文	Li Yaping\|Qi Li\|Ma Huimin\|
4	Fabrication of nylon membrane-based microfluidic chips and its application in color sensing of glucose	期刊论文	Jun Yang, Li Qi*, Huimin Ma, Yi Chen\|
5	基于肾缺血的酶反应及酶抑制剂筛选的CLE-CE研究	会议论文
6	Fluorescent probe forturn-on sensing of L-cysteine by ensemble of AuNCs and polymer protected AuNPs	期刊论文	Juan Qiao\|Nan Li\|Li Qi\|Shufeng Zhang\|
7	Ratiometric fluorescent polymeric thermometer: forthermogenesis investigation in living cells	期刊论文	Li Qi\|Ping Dong\|Xiao-Yu Mu\|Dong-Pyo Kim\|
8	Study on the decrease of renal D-amino acid oxidase activity in the rat after renal ischemia by chiral ligand exchange capillary electrophoresis	期刊论文	Li Qi\|Yuqing Lin\|Lanquan Mao\|Yi Chen\|
9	Preparation of a novel polymer monolith with functional polymer brushes by two-step atom transfer radical polymerization for trypsin-based bioreactor	期刊论文	Yaping Li\|Juan Qiao\|Fuyi Wang\|Yi Chen\|
10	Study on alanine aminotransferase kinetics by microchip electrophoresis	期刊论文	Li Qi\|Juan Qiao\|Haizhi Zhang\|Huimin Ma\|
11	A new chiral ligand exchange capillary electrophoresis system based on Zn(II)-L-leucine complexes coordinating with β-cyclodextrin and its application in screening tyrosinase inhibitors	期刊论文	Yuan Su\|Li Qi\|Xiaoyu Mu\|
12	Preparation of AAILs as chiral ligands of Zn(II) complexes in chiral ligand exchange capillary electrophoresis (CLE-CE) and its application	会议论文
13	A well-defined block copolymer serving as surfactants in separation of 1, 4-dihydropyridines by open tubular capillary eletrochromatography	期刊论文	Ying Shen\|HuijuanYan\|Peiyong Xin\|Huimin Ma\|
14	Ratiometric fluorescent probe based on gold nanoclusters and alizarin red-boronic acid for monitoring glucose in brain microdialysate	期刊论文	Xiaoping Zhou\|Dan Li\|Zongxiu Nie\|Lanqun Mao\|
15	Development of a capillary electrophoresis system withMn(II) complexes and β-cyclodextrin as the dual chiral selectors forenantioseparation of dansyl amino acids and its application in screening enzymeinhibitors	期刊论文	Yuan Su\|Xiaoyu Mu\|Li Qi\|
16	Study on MCE-LIF method for thehydrolysis of L-glutamine with L-asparaginase enzyme reactor based on GNPs	会议论文
17	Chiral separation using capillary electromigration techniques based on ligand exchange principle	期刊论文	Haizhi Zhang\|Li Qi\|Lanqun Mao\|Yi Chen\|
18	Ionic liquids with amino acids as cations: novel chiral ligands in chiral ligand-exchange capillary electrophoresis	期刊论文	Haizhi Zhang\|Ying Shen\|Juan Qiao\|Huimin Ma\|
19	Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging	期刊论文	Mu Xiaoyu\|Qi Li\|Deng Jingjing\|Mao Lanqun\|
20	Intracellular temperature sensing by a ratiometric fluorescent polymer thermometer	期刊论文	Qin Jiang\|Xinzheng Yang\|Xiaoyu Mu\|Lanqun Mao\|
21	基于蛋白质及手性氨基酸分析的生物色谱新方法研究	奖励
22	手性配体交换毛细管电泳新体系构建及其应用研究	会议论文
23	Enantioseparation of amino acids and dipeptides by chiral ligand exchange capillary electrophoresis based on Zn(II)-L-hydroxyproline complexes coordinating with cyclodextrins	期刊论文	Li Qi\|Juan Qiao,\|Xinzheng Yang\|Huimin Ma\|
24	Biochromatography and its application	会议论文
25	A chiral ligand exchange CE system for studying theinhibitory effect of kojic acid on tyrosinase	期刊论文	Li Qi\|Xiaoyu Mu\|Juan Qiao\|Minglin Wang\|
26	Study on chiral separationof amino acids and enzymatic kinetics by microchip electrophoresis	会议论文
27	Facile preparation of surface-exchangeable core@shell iron oxide@gold nanoparticles for magnetic solid-phase extraction: Use of gold shell as the intermediate platform for versatile adsorbents with varying self-assembled monolayers	期刊论文	Yaping Li\|Li Qi\|Ying Shen\|Huimin Ma\|
28	Facile Fabrication of Polymeric Ionic Liquid Grafted Porous Polymer Monolith for Mixed-Mode High Performance Liquid Chromatography	期刊论文	Li Qi\|Ying Shen\|Haizhi Zhang\|Huimin Ma\|
29	利用原子转移自由基聚合方法制备一种新型聚合物整体柱固相萃取材料初探	期刊论文	齐莉\|乔娟\|毛兰群\|陈义\|
30	Preparation of L-lysine derivedILs as the chiral ligands of Zn(II) complexes in ligand exchange capillaryelectrophoresis	会议论文
31	Immobilization of Trypsin via Reactive Polymer Grafting from Magnetic Nanoparticles for Microwave-assisted Digestion~Journal of Materials Chemistry B	期刊论文	Qi Li\|Qiao Juan\|Wang Fuyi\|Mao Lanqun\|
32	Reactive Polymer as a Versatile Toolbox for Construction of Multifunctional Superparamagnetic Nanocomposites	期刊论文	Li Qi\|Juan Qiao\|Lanqun Mao\|Yi Chen\|
33	l-Lysine-derived ionic liquids as chiral ligands of Zn(II) complexes used in ligand-exchange CE	期刊论文	Qi Li\|Shen Ying\|Qiao Juan\|Mao Lanqun\|
34	Study on glutamic pyruvic transaminase kinetics by microchip electrophoresis	期刊论文	Xiaoyu Mu, Li Qi*, J Qiao, HZ Zhang, HM Ma\|
35	Preparation of multifunctional polymers by RAFT method with droplet microfluidic approach for cancer cells imaging	会议论文
36	Determination of preservatives in soft drinks by capillary electrophoresis with ionic liquids as the electrolyte additives	期刊论文	Bingbing Sun\|Li Qi\|Minling Wang\|
37	Study on sodium benzoate bychiral ligand exchange capillary electrophoresis based on its inhibitoryactivity in D-amino acid oxidase mediated oxidation of D-serine	会议论文
38	新型AAILs的合成制备及其酶反应动力学的CLE-CE研究	会议论文
39	智能型色谱整体固定相的研究进展	期刊论文	沈莹\|齐莉\|陈义\|毛兰群\|
40	One-pot synthesis of tyrosine-stabilized fluorescent gold nanoclusters and its application as turn-on sensor for Al3+ ions and turn-off sensor for Fe3+ ions	期刊论文	Xiaoyu Mu\|Li Qi\|Juan Qiao\|Huimin Ma\|
41	Development of new chiral ligand exchange capillary electrophoresis system with amino acid ionic liquids ligands and its application in studying the kinetics of L-amino acid oxidase	期刊论文	Bingbing Sun\|Xiaoyu Mu\|Li Qi\|
42	Novel chiral ligand exchange capillary electrophoresis system with amino acid ionic liquid as chiral ligand and its application	会议论文
43	Poly(2-vinyl-4,4-dimethylazlactone-functionalized magnetic nanoparticles as carriers for enzyme immobilization and its application	期刊论文	Juan Qiao\|Li Qi\|Ping Dong\|Huimin Ma\|
44	Study on MCE-LIF method for the hydrolysis of L-glutamine with L-asparaginase enzyme reactor based on GNPs	会议论文
45	手性分析及酶反应动力学的微芯片电泳技术研究	会议论文
46	Novel chiral ligand exchangecapillary electrophoresis system with amino acid ionic liquid as chiral ligandand its application	会议论文
47	Biochromatography and itsapplication	会议论文
48	A chiral ligand exchange CE system for studying the inhibitory effect of kojic acid on tyrosinase	期刊论文	Qi Li\|Mu Xiaoyu\|Qiao Juan\|Wang Minglin\|
49	Preparation of AAILs as chiralligands of Zn(II) complexes in chiral ligand exchange capillary electrophoresis(CLE-CE) and its application	会议论文
50	Design and Fabrication of a Three Dimensional Spiral Micromixer	期刊论文	Yang Jun\|Qi Li\|Chen Yi\|Ma Huimin\|
51	Facile one-pot synthesis of L-proline-stabilized fluorescent gold nanoclusters and its application as sensing probes for serum iron	期刊论文	Qiao Juan\|Hou Jian\|Nie Zongxiu\|Ma Huimin\|
52	Influence of ionic liquids as electrolyte additives on chiral separation of dansylated amino acids by using Zn(II) complex mediated chiral ligand exchange CE	期刊论文	Mu Xiaoyu\|Zhou Xiaoping\|Li Dan\|Mao Lanqun\|
53	A novel chiral ligand exchange capillary electrophoresis system with amino acid ionic liquid as ligand and its application in screening D-amino-acid oxidase inhibitors	期刊论文	Ying Shen\|Haizhi Zhang\|Juan Qiao\|Huimin Ma\|
54	The facile fabrication of polymeric ionic liquid grafted porous polymer monolith for mixed-mode high performance liquid chromatography	期刊论文	Li Qi\|Ying Shen\|Haizhi Zhang\|Huimin Ma\|
55	A Colorimetric Sensor for Determination of Cysteine by Carboxymethyl Cellulose-Functionalized Gold Nanoparticles	期刊论文	Li Qi\|Juanjuan Tan\|Ruigang Liu\|Fuyi Wang\|
56	新型温敏聚合物纳米金酶反应器的制备及其蛋白酶解研究	会议论文
57	合成制备氨基酸离子液体和基于CLE-CE的手性分析及其酶反应动力学研究	会议论文
58	Preparation of an aminoacid-based polymer monolith for trimodal chromatography	期刊论文	Yong Shen\|Li Qi\|Juan Qiao\|Zhibo Li\|
59	Thermoresponsive Oligo(ethylene glycol)-Based Polymer Brushes on Polymer Monolith for All-Aqueous Chromatography	期刊论文	Qi Li\|Shen Ying\|Li Yaping\|Chen Yi\|
60	Construction of D-amino acid oxidase reactor based on magnetic nanoparticles modified by reactive polymer and its application in screening enzyme inhibitors	期刊论文	Juan Qiao\|Li Qi\|Ying Liu\|Huimin Ma\|
61	A versatile method for the preparation of poly-acrylamides derivatives functionalized thermo-responsive gold nanoparticles	期刊论文	Qiao Juan\|Qi Li\|Mu Xiaoyu\|
62	Novel Oligo(ethylene glycol)-Based Molecularly Imprinted Magnetic Nanoparticles for Thermally Modulated Capture and Release of Lysozyme	期刊论文	Li Qi\|Ying Shen\|Juan Qiao\|Yi Chen\|
63	Macroporous polymer monoliths with a well-defined three dimensional skeletal morphology derived from a novel phase separator for HPLC	期刊论文	Ying Shen\|Li Qi\|Lanqun Mao\|
64	Thermal responsive fluorescent block copolymer for intracellular temperature sensing	期刊论文	Cui Qi\|Dihua Shangguan\|Lanqun Mao\|Yi Chen\|
65	A passive mixer with changeable mixing mechanism	期刊论文	Jun Yang, Li Qi*, Yi Chen, Huimin Ma\|
66	Novel chiral ligand exchangecapillary electrophoresis system with amino acid ionic liquid as chiral ligandand its application	会议论文

查看更多信息请先登录或注册

再问科研

相关项目

趋势报告

经验分享