基于kealiinine类海洋生物碱的新型抗病毒剂的设计合成、构效关系及作用机制研究

21772145
2017
B0706.药物化学生物学
王兹稳
面上项目
教授
天津师范大学
64万元
抗病毒活性;Kealiinine;烟草花叶病毒;天然产物;构效关系
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 Marine-natural-products for biocides development: first discovery of meridianin alkaloids as antiviral and anti-phytopathogenic-fungus agents 期刊论文 Dong Ji;Huang Shisheng;Hao Yanan;Wang Ziwen;Liu Yuxiu;Li Yongqiang;Wang Qingmin
2 Marine Natural Product for Pesticide Candidate: Pulmonarin Alkaloids as Novel Antiviral and Anti-Phytopathogenic-Fungus Agents. 期刊论文 Zhang Mingjun;Ding Xin;Kang Jin;Gao Yongyue;Wang Ziwen;Wang Qingmin
3 Discovery, Structural Optimization, and Mode of Action of Essramycin Alkaloid and Its Derivatives as Anti-Tobacco Mosaic Virus and Anti-Phytopathogenic Fungus Agents 期刊论文 Wang Tienan;Yang Shan;Li Hongyan;Lu Aidang;Wang Ziwen;Yao Yingwu;Wang Qingmin
4 Discovery of Pimprinine Alkaloids as Novel Agents against a Plant Virus 期刊论文 Liu Bin;Li Rui;Li Yanan;Li Songyi;Yu Jin;Zhao Binfen;Liao Ancai;Wang Ying;Wang Ziwen;Lu Aidang;Liu Yuxiu;Wang Qingmin
5 咪唑类生物碱在治疗植物病毒和病菌中的应用 专利 王兹稳;汪清民;刘玉秀;郭朋滨
6 Discovery of glyantrypine-family alkaloids as novel antiviral and anti-phytopathogenic-fungus agents 期刊论文 Hao Yanan;Yu Mo;Wang Kaihua;Zhu Binbing;Wang Ziwen;Liu Yuxiu;Ma Dejun;Wang Qingmin
7 脱氢蟾蜍色胺衍生物及其制备方法和农业用途 专利 王兹稳;张铭君;卢爱党
8 一种光促进的由磺酰氯制备磺酸盐和磺酰胺的新方法 专利 王兹稳;张铭君;丁鑫
9 Discovery and Nanosized Preparations of (S,R)-Tylophorine Malate as Novel anti-SARS-CoV-2 Agents 期刊论文 Wang Ziwen;Ye Fei;Feng Yue;Xiao Wen;Song Hongjian;Zhao Li;Lu Roujian;Huang Baoying;Liu Yuxiu;Wang Wenling;Li Yongqiang;Ding Yi;Zheng Yanlong;Song Xiangrong;Tan Wenjie;Wang Qingmin
10 Marine-Natural-Product Development: First Discovery of Nortopsentin Alkaloids as Novel Antiviral, Anti-phytopathogenic-Fungus, and Insecticidal Agents 期刊论文 Ji Xiaofei;Guo Jincheng;Liu Yuxiu;Lu Aidang;Wang Ziwen;Li Yongqiang;Yang Shaoxiang;Wang Qingmin
11 Luotonin A and Its Derivatives as Novel Antiviral and Antiphytopathogenic Fungus Agents 期刊论文 Hao Yanan;Wang Kaihua;Wang Ziwen;Liu Yuxiu;Ma Dejun;Wang Qingmin
12 Optimization, Structure-Activity Relationship, and Mode of Action of Nortopsentin Analogues Containing Thiazole and Oxazole Moieties 期刊论文 Guo Jincheng;Hao Yanan;Ji Xiaofei;Wang Ziwen;Liu Yuxiu;Ma Dejun;Li Yongqiang;Pang Huailin;Ni Jueping;Wang Qingmin
13 Generation and precise control of sulfonyl radicals: visible-light-activated redox-neutral formation of sulfonates and sulfonamides 期刊论文 Zhang Mingjun;Ding Xin;Lu Aidang;Kang Jin;Gao Yongyue;Wang Ziwen;Li Hongyan;Wang Qingmin
14 Pityriacitrin marine alkaloids as novel antiviral and anti-phytopathogenic-fungus agents 期刊论文 Wang Tie-Nan;Yang Shan;Shi Shao-Yang;Yuan Wen-Ying;Chen Jian-Xin;Duan Zhong-Yu;Lu Ai-Dang;Wang Zi-Wen;Wang Qing-Min
15 基于海洋天然产物的活性先导发现 会议论文 王兹稳;冀晓霏;郭朋滨;刘玉秀;汪清民
16 Discovery of Tryptanthrins as Novel Antiviral and Anti-Phytopathogenic-Fungus Agents 期刊论文 Hao Yanan;Guo Jincheng;Wang Ziwen;Liu Yuxiu;Li Yongqiang;Ma Dejun;Wang Qingmin
17 NATURAL PRODUCTS FOR BIOCIDES DISCOVERY: DISCOVERY OF ARUNDINE AND IT'S DERIVATIVES AS NOVEL ANTIVIRAL AND ANTI-PHYTOPATHOGENIC-FUNGUS AGENTS 期刊论文 Liao Ancai;Jin Shengli;Wang Ziwen;Wang Qingmin
18 The photoredox-catalyzed hydrosulfamoylation of styrenes and its application in the novel synthesis of naratriptan 期刊论文 Zhang Mingjun;Chen Miaomiao;Ding Xin;Kang Jin;Gao Yongyue;He Xingxing;Wang Ziwen;Lu Aidang;Wang Qingmin
19 一种制备那拉曲坦及其衍生物的新方法 专利 王兹稳;陈淼淼;张铭君
20 Design, synthesis, and bioactivity of nortopsentin analogues containing 1,2,4-triazole moieties 期刊论文 Zhao Xinyu;Liao Ancai;Zhang Fan;Zhao Qi;Zhou Lijia;Fan Jingjing;Zhang Zheng;Wang Ziwen;Wang Qingmin
21 Efficient synthesis of SCF3-substituted tryptanthrins by a radical tandem cyclization 期刊论文 Guo Jincheng;Hao Yanan;Li Gang;Wang Ziwen;Liu Yuxiu;Li Yongqiang;Wang Qingmin
22 生物碱pulmonarin B衍生物及其合成和在防治植物病毒和病菌病中的应用 专利 王兹稳;张铭君;高咏悦
23 一种由脂肪胺基磺酰氯制备烷基磺酰胺的新方法 专利 王兹稳;贺星星;张铭君
24 Streptindole and Its Derivatives as Novel Antiviral and Anti-Phytopathogenic Fungus Agents 期刊论文 Kang Jin;Gao Yongyue;Zhang Mingjun;Ding Xin;Wang Ziwen;Ma Dejun;Wang Qingmin
25 Naamines and Naamidines as Novel Agents against a Plant Virus and Phytopathogenic Fungi 期刊论文 Guo Pengbin;Li Gang;Liu Yuxiu;Lu Aidang;Wang Ziwen;Wang Qingmin
26 生物碱pulmonarin B的合成及在防治植物病毒和病菌病中的应用 专利 王兹稳;张铭君;丁鑫
27 Formation of Amidinyl Radicals via Visible-Light-Promoted Reduction of N-Phenyl Amidoxime Esters and Application to the Synthesis of 2-Substituted Benzimidazoles 期刊论文 Li Gang;He Ru;Liu Qiang;Wang Ziwen;Liu Yuxiu;Wang Qingmin
28 Natural Products for Drug Discovery: Discovery of Gramines as Novel Agents against a Plant Virus 期刊论文 Lu Aidang;Wang Tienan;Hui Hao;Wei Xiaoye;Cui Weihao;Zhou Chunlv;Li Hongyan;Wang Ziwen;Guo Jincheng;Ma Dejun;Wang Qingmin
29 Naamine类衍生物及其制备方法和在治疗植物病毒和病菌病中的应用 专利 王兹稳;汪清民;刘玉秀;郭朋滨
30 生物碱streptindole及其衍生物在防治植物病毒病菌病中的应用 专利 王兹稳;髙咏悦;张铭君
31 Toad Alkaloid for Pesticide Discovery: Dehydrobufotenine Derivatives as Novel Agents against Plant Virus and Fungi 期刊论文 Tian Zhaoyong;Liao Ancai;Kang Jin;Gao Yongyue;Lu Aidang;Wang Ziwen;Wang Qingmin
32 Marine Natural Products for Drug Discovery: First Discovery of Kealiinines A-C and Their Derivatives as Novel Antiviral and Antiphytopathogenic Fungus Agents 期刊论文 Li Gang;Guo Jincheng;Wang Ziwen;Liu Yuxiu;Song Haibin;Wang Qingmin
33 基于海洋天然产物的新型抗病毒活性分子发现 会议论文 王兹稳;张铭君;康锦;郝亚男;汪清民
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享