从IFN信号通路寻找影响CHB患者IFN-α疗效差异的关键基因并证实其功能

81572067
2015
H2605.分子生物学检验
欧启水
面上项目
教授
福建医科大学
65万元
疗效;慢性乙型肝炎;干扰素;单核苷酸多态性;功能
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Genetic variants in NTCP exon gene are associated with HBV infection status in a Chinese Han population. 期刊论文 Wu Wennan;Zeng Yongbin;Lin Jinpiao;Wu Yingying;Chen Tianbin;Xun Zhen;Ou Qishui
2 Polymorphisms of CYP27B1 are associated with IFN efficacy in HBeAg-positive patients. 期刊论文 Wu Yingying;Zeng Yongbin;Wu Wennan;Lin Jinpiao;Ou Qishui
3 Toll-like receptors, long non-coding RNA NEAT1, and RIG-I expression are associated with HBeAg-positive chronic hepatitis B patients in the active phase. 期刊论文 Zeng Yongbin;Wu Wennan;Fu Ya;Chen Shanjian;Chen Tianbin;Yang Bin;Ou Qishui
4 Association of serum total cholesterol with pegylated interferon-alpha treatment in HBeAg-positive chronic hepatitis B patients 期刊论文 Xun Zhen;Lin Jin Piao;Liu Can;Huang Jin Lan;Shen Ye;Xu Si Yi;Wu Wen Nan;Ou Qi Shui
5 慢性乙型肝炎患者HBsAg和抗HBs共存的发生机制及其临床意义 期刊论文 傅晓春;刘灿;欧启水
6 Characterization and Clinical Significance of Natural Variability in Hepatitis B Virus Reverse Transcriptase in Treatment-Naive Chinese Patients by Sanger Sequencing and Next-Generation Sequencing. 期刊论文 Fu Ya;Zeng Yongbin;Chen Tianbin;Chen Huijuan;Lin Ni;Lin Jinpiao;Liu Xiaofeng;Huang Er;Wu Songhang;Wu Shu;Xu Siyi;Wang Long;Ou Qishui
7 医院就诊人群HBsAg与抗HBs双阳性HBV感染者的流行病学与分子病毒学特征 期刊论文 傅晓春;陈静;叶爱珠;陈惠娟;荀振;曾勇彬;刘灿;林锦骠;欧启水
8 Prediction value of serum HBV large surface protein in different phases of HBV infection and virological response of chronic hepatitis B patients. 期刊论文 Liu Can;Wu Wennan;Shang Hongyan;Lin Sheng;Xun Zhen;Huang Er;Lin Jinpiao;Yang Bin;Ou Qishui
9 HBV基因突变及其临床意义研究进展 期刊论文 刘灿;欧启水
10 Mutation in the S gene of hepatitis B virus and anti-HBs subtype-nonspecificity contributed to the co-existence of HBsAg and anti-HBs in patients with chronic hepatitis B virus infection 期刊论文 Fu Xiaochun;Chen Jing;Chen Huijuan;Lin Jinpiao;Xun Zhen;Li Shiqi;Liu Can;Zeng Yongbin;Chen Tianbin;Yang Bin;Ou Qishui
11 Application strategies of serum HBV DNA detection in HBV infection patients: A retrospective study of 5611 specimens. 期刊论文 Liu Can;Wu Wennan;Shang Shongyan;Huang Er;Xun Zhen;Lin Jinpiao;Chen Tianbin;Yang Bin;Chen Jing;Ou Qishui
12 RIG-I enhances interferon-alpha response by promoting antiviral protein expression in patients with chronic hepatitis B. 期刊论文 Wu Shu;Lin Jinpiao;Fu Ya;Ou Qishui
13 An ultrasensitive fluorescence aptasensor for carcino-embryonic antigen detection based on fluorescence resonance energy transfer from upconversion phosphors to Au nanoparticles 期刊论文 Li Xiang Hui;Sun Wei Ming;Wu Juan;Gao Yao;Chen Jing Hua;Chen Min;Ou Qi Shui
14 Establishment of Coamplification at Lower Denaturation Temperature PCR/Fluorescence Melting Curve Analysis for Quantitative Detection of Hepatitis B Virus DNA, Genotype, and Reverse Transcriptase Mutation and Its Application in Diagnosis of Chronic Hepatitis B 期刊论文 Liu Can;Lin Jinpiao;Xun Zhen;Huang Jinlan;Huang Er;Chen Tianbin;He Yujue;Lin Ni;Yang Bin;Ou Qishui
15 血清乙肝病毒颗粒的存在形式及其临床价值 期刊论文 欧启水;郭健慧
16 Diagnostic value of serum pgRNA detection in HBV-infected patients with different clinical outcomes. 期刊论文 Lin Ni;Ye Aizhu;Lin Jinpiao;Liu Can;Huang Jinlan;Fu Ya;Wu Songhang;Xu Siyi;Wang Long;Ou Qishui
17 Application strategies of serum HBV DNA detection in HBV infection patients: A retrospective study of 5611 specimens 期刊论文 Liu Can;Wu Wennan;Shang Shongyan;Huang Er;Xun Zhen;Lin Jinpiao;Chen Tianbin;Yang Bin;Chen Jing;Ou Qishui
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