组蛋白变体对脑发育的调控机制研究

31730033
2017
C0901.分子与细胞神经生物学
焦建伟
重点项目
研究员
中国科学院动物研究所
315万元
增殖;干细胞;分化;神经前体细胞;组蛋白修饰
2018-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 CD93 negatively regulates astrogenesis in response to MMRN2 through the transcriptional repressor ZFP503 in the developing brain 期刊论文 Liang Qingli;Su Libo;Zhang Dongming;Jiao Jianwei
2 H2A.Z.1 crosstalk with H3K56-acetylation controls gliogenesis through the transcription of folate receptor. 期刊论文 Su Libo;Xia Wenlong;Shen Tianjin;Liang Qingli;Wang Wenwen;Li Hong;Jiao Jianwei
3 Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development 期刊论文 Mengtian Zhang;Libo Su;Wenwen Wang;Chenxiao Li;Qingli Liang;Fen Ji;Jianwei Jiao
4 Human SERPINA3 induces neocortical folding and improves cognitive ability in mice 期刊论文 Jinyue Zhao;Chao Feng;Wenwen Wang;Libo Su;Jianwei Jiao
5 Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression. 期刊论文 Ji Fen;Wang Wenwen;Feng Chao;Gao Fei;Jiao Jianwei
6 TCF20 dysfunction leads to cortical neurogenesis defects and autistic-like behaviors in mice. 期刊论文 Feng Chao;Zhao Jinyue;Ji Fen;Su Libo;Chen Yihui;Jiao Jianwei
7 Nap1l1 Controls Embryonic Neural Progenitor Cell Proliferation and Differentiation in the Developing Brain. 期刊论文 Qiao Huimin;Li Yanxin;Feng Chao;Duo Shuguang;Ji Fen;Jiao Jianwei
8 Loss of Rsph9 causes neonatal hydrocephalus with abnormal development of motile cilia in mice 期刊论文 Zou Wenzheng;Lv Yuqing;Liu Zux Iang;Xia Pengyan;Li Hong;Jiao Jianwei
9 MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors 期刊论文 Ma Hongyan;Su Libo;Xia Wenlong;Wang Wenwen;Tan Guohe;Jiao Jianwei
10 The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. 期刊论文 Wang Wenwen;Su Libo;Ji Fen;Zhang Dongming;Wang Yanyan;Zhao Jinyue;Jiao Ross Dingyan;Zhang Mengtian;Huang Enyu;Jiang Hong;Zhang Jingjing;Jiao Jianwei
11 Acquisition of functional neurons by direct conversion: Switching the developmental clock directly. 期刊论文 Chen Shuangquan;Zhang Juan;Zhang Dongming;Jiao Jianwei
12 Decoding the temporal and regional specification of microglia in the developing human brain. 期刊论文 Li Yanxin;Li Zhongqiu;Yang Min;Wang Feiyang;Zhang Yuehong;Li Rong;Li Qian;Gong Yunxia;Wang Binhong;Fan Baoguang;Wang Chunyue;Chen Lei;Li Hong;Ong Jennie;Teng Zhaoqian;Jin Lei;Wang Yan-Ling;Du Peng;Jiao Jianwei
13 PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain. 期刊论文 Su Libo;Lei Xuepei;Ma Hongyan;Feng Chao;Jiang Jing;Jiao Jianwei
14 一种诱导成纤维细胞转分化为神经元细胞的方法及其应用 专利 焦建伟;史子啸
15 Endothelial Cells Mediated by UCP2 Control the Neurogenic‐to‐Astrogenic Neural Stem Cells Fate Switch During Brain Development 期刊论文 Wenwen Wang;Libo Su;Yanyan Wang;Chenxiao Li;Fen Ji;Jianwei Jiao
16 Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. 期刊论文 Li Yanxin;Jiao Jianwei
17 USP10 基因和/或Ascl1 基因在诱导成纤维细胞转分化为神经元细胞的应用及方法 专利 焦建伟;张东明
18 RNF20 controls astrocytic differentiation through epigenetic regulation of STAT3 in the developing brain. 期刊论文 Liang Qingli;Xia Wenlong;Li Wei;Jiao Jianwei
19 Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. 期刊论文 Li Zhongqiu;Li Yanxin;Jiao Jianwei
20 Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. 期刊论文 Zhang Dongming;Liu Chang;Li Hong;Jiao Jianwei
21 Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. 期刊论文 Xia Wenlong;Su Libo;Jiao Jianwei
22 UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. 期刊论文 Lei Xuepei;Jiao Jianwei
23 Histone Variants and Histone Modifications in Neurogenesis. 期刊论文 Zhang Mengtian;Zhao Jinyue;Lv Yuqing;Wang Wenwen;Feng Chao;Zou Wenzheng;Su Libo;Jiao Jianwei
24 Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. 期刊论文 Shen Tianjin;Ji Fen;Wang Yuanyuan;Lei Xuepei;Zhang Dongming;Jiao Jianwei
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