基于镉诱导氧化应激的神经细胞自噬体积累介导凋亡及调控分子机理研究

81873781
2018
H0912.神经退行性变及相关疾病
陈龙
面上项目
教授
南京师范大学
56万元
镉;氧化应激;神经细胞;凋亡;自噬体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 NOX2-derived hydrogen peroxide impedes the AMPK/Akt-mTOR signaling pathway contributing to cell death in neuronal cells 期刊论文 Ruijie Zhang;Chunxiao Liu;Liu Yang;Tong Ji;Nana Zhang;Xiaoqing Dong;Xin Chen;Jing Ma;Wei Gao;Shile Huang;Long Chen
2 Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells 期刊论文 Xiaoqing Dong;Rui Zhao;Yue Li;Qianyun Yu;Xin Chen;Xiaoyu Hu;Jing Ma;Xiaoling Chen;Shile Huang;Long Chen
3 Metformin attenuates cadmium-induced neuronal apoptosis in vitro via blocking ROS-dependent PP5/AMPK-JNK signaling pathway 期刊论文 Xiaoling Chen;Wen Wu;Baoming Gong;Long Hou;Xiaoqing Dong;Chong Xu;Rui Zhao;Qianyun Yu;Zhihan Zhou;Shile Huang;Long Chen
4 Metformin attenuates cadmium-induced neuronal apoptosis in vitro viablocking ROS-dependent PP5/AMPK-JNK signaling pathway 会议论文 Xiaoling Chen;Wen Wu;Baoming Gong;Long Hou;Xiaoqing Dong;Chong Xu;Rui Zhao;Qianyun Yu;Zhihan Zhou;Shile Huang;Long Chen
5 Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells 期刊论文 Rui Zhao;Qianyun Yu;Long Hou;Xiaoqing Dong;Hai Zhang;Xiaoling Chen;Zhihan Zhou;Jing Ma;Shile Huang;Long Chen
6 Rapamycin ameliorates cadmium-induced autophagic flux impairment against apoptosis via XIAP pathway in neuronal cells 会议论文 Long Hou;Yajie Yao;Liu Yang;Xiaoling Chen;Ming Xu;Long Chen
7 Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells 会议论文 Rui Zhao;Qianyun Yu;Long Hou;Xiaoqing Dong;Hai Zhang;Xiaoling Chen;Zhihan Zhou;Jing Ma;Long Chen
8 Metformin attenuates Cd-induced neuronal apoptosis via blocking ROS-dependent AMPK/PP5-JNK signaling pathway 会议论文 Xiaoling Chen;Wen Wu;Baoming Gong;Long Hou;Xiaoqing Dong;Long Chen
9 Neuroprotection of resveratrol against cadmium-poisoning acts through dual inhibition of mTORC1/2 signaling 期刊论文 Chunxiao Liu;Ruijie Zhang;Liu Yang;Tong Ji;Cuilan Zhu;Beibei Liu;Hai Zhang;Chong Xu;Nana Zhang;Shile Huang;Long Chen
10 Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells 会议论文 Rui Zhao;Qianyun Yu;Long Hou;Xiaoqing Dong;Hai Zhang;Xiaoling Chen;Zhihan Zhou;Jing Ma;Shile Huang;Long Chen
11 Cadmium results in accumulation of autophagosomes-dependent apoptosis through activating Akt-impaired autophagic flux in neuronal cells 期刊论文 Hai Zhang;Xiaoqing Dong;Rui Zhao;Ruijie Zhang;Chong Xu;Xiaoxue Wang;Chunxiao Liu;Xiaoyu Hu;Shile Huang;Long Chen
12 Cadmium Impairs Autophagy Leading to Apoptosis by Ca2+-Dependent Activation of JNK Signaling Pathway in Neuronal Cells 期刊论文 Chong Xu;Sujuan Chen;Ming Xu;Xiaoling Chen;Xiaoxue Wang;Hai Zhang;Xiaoqing Dong;Ruijie Zhang;Xin Chen;Wei Gao;Shile Huang;Long Chen
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