NF-κB信号转导途径的植物环肽RAs新类型小分子探针作用机制研究
91013002
2010
B0703.天然产物化学生物学
谭宁华
重大研究计划
教授
中国科学院昆明植物研究所
60万元
作用机制;RAs;新型小分子探针;植物环肽;NF-κB信号通路
2011-01-01到2013-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 大叶茜草中环肽类成分的研究 | 期刊论文 | 邝彬|范君婷|赵思蒙|谭宁华| |
| 2 | Antitumor Cyclic Hexapeptides from Rubia Plants: History, Chemistry, and Mechanism (2005-2011) | 期刊论文 | Zhao, Si Meng|Kuang, Bin|Fan, Jun Ting|Yan, He|Xu, Wen Yan|Tan, Ning Hua| |
| 3 | Isolation and characterization of cytotoxic cyclotides from Viola philippica | 期刊论文 | He, Wenjun|Chan, Lai Yue|Zeng, Guangzhi|Daly, Norelle L.|Craik, David J.|Tan, Ninghua| |
| 4 | Astataricusones A-D and Astataricusol A, Five New Anti-HBV Shionane-Type Triterpenes from Aster tataricus L. f. | 期刊论文 | Zhou, Wen-Bing|Zeng, Guang-Zhi|Xu, Hui-Min|He, Wen-Jun|Tan, Ning-Hua| |
| 5 | Benzoic Acid Allopyranosides and Lignan Glycosides from the Twigs of Keteleeria evelyniana | 期刊论文 | He, Wen Jun|Fu, Zhao Hui|Han, Hong Jin|Yan, He|Zeng, Guang Zhi|Ji, Chang Jiu|Chu, Hong Biao|Zhang, Yu Mei|Tan, Ning Hua| |
| 6 | Astins K–P, six new chlorinated cyclopentapeptides from Aster tataricus | 期刊论文 | Hui-Min Xu|Guang-Zhi Zeng|Wen-Bing Zhou|Wen-Jun He|Ning-Hua Tan| |
| 7 | Chemical Progress in Cyclopeptide-containing Traditional Medicines Cited in Chinese Pharmacopoeia | 期刊论文 | Tan Ninghu|Kuang Bin|Peng Wenwen|He Wenjun|Xu Huimin|Ji Changjiu|Han Jing|Zheng Yuqing|Song Weiwu| |
| 8 | [One new chroman glycoside derivative from unmatured fruits of Citrus aurantium]. | 期刊论文 | Peng, Wen-Wen|Yan, He|Tan, Ning-Hua| |
| 9 | Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction | 期刊论文 | Yang Sun|Wei Chen|Jun-Ting Fan|Ran Song|Lu Wang|Yan-Hong Gu|Guang-Zhi Zeng|Yan Shen|Xue-Feng Wu| |
| 10 | Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana | 期刊论文 | Ji, Chang-Jiu|Zeng, Guang-Zhi|Han, Jing|He, Wen-Jun|Zhang, Yu-Mei|Tan, Ning-Hua| |
| 11 | Biologically Active Arborinane-Type Triterpenoids and Anthraquinones from Rubia yunnanensis | 期刊论文 | Fan, Jun-Ting|Kuang, Bin|Zeng, Guang-Zhi|Zhao, Si-Meng|Ji, Chang-Jiu|Zhang, Yu-Mei|Tan, Ning-Hua| |
| 12 | A new family of cystine knot peptides from the seeds of Momordica cochinchinensis | 期刊论文 | Lai Yue Chan|Wenjun He|Ninghua Tan|Guangzhi Zeng|David J. Craik|Norelle L. Daly| |
| 13 | Novel Inhibitor Cystine Knot Peptides from Momordica charantia | 期刊论文 | Tan, Ning-Hua|Chan, Lai Yue|Clark, Richard J.|Tang, Jun|Zeng, Guang-Zhi|Franco, Octavio L.|Cantacessi, Cinzia|Craik, David J.|Daly, Norelle L.| |
| 14 | Anti-angiogenesis and immunomodulatory activities of an anti-tumor sesquiterpene bigelovin isolated from Inula helianthus-aquatica | 期刊论文 | Clara B.S. Lau|Ben C.L. Chan|Hin-Fai Kwok|Yuk-Lau Wong|Hoi-Wing Leung|Chang-Jiu Ji|Kwok-Pui Fung|Ping-Chung Leung|Ning-Hua Tan| |
| 15 | A prenylated xanthone and antiproliferative compounds from leaves of Pentadesma butyracea | 期刊论文 | Michel Feussi Tala|Hippolyte Kamdem Wabo|Guang-Zhi Zeng|Chang-Jiu Ji|Pierre Tane|Ning-Hua Tan| |
| 16 | Inhibitory activity of eudesmane sesquiterpenes from Alpinia oxyphylla on production of nitric oxide | 期刊论文 | Xu, Junju|Ji, Changjiu|Zhang, Yumei|Su, Jia|Li, Yan|Tan, Ninghua| |
| 17 | New Lignans from Jatropha curcas Linn | 期刊论文 | Xu, Jun Ju|Tan, Ning Hua| |
| 18 | Tataricins A and B, two novel cyclotetrapeptides from Aster tataricus, and their absolute configuration assignment | 期刊论文 | Hui-Min Xu|Hua Yi|Wen-Bing Zhou|Wen-Jun He|Gang-Zhi Zeng|Wen-Yan Xu|Ning-Hua Tan| |
| 19 | Coumarins from roots of Clausena excavata | 期刊论文 | Peng, Wen-Wen|Zheng, Yu-Qing|Chen, Yi-Shan|Zhao, Si-Meng|Ji, Chang-Jiu|Tan, Ning-Hua| |
| 20 | Multiple hydrogen-bonding interactions between macrocyclic triurea and F-, Cl-, Br-, I- and NO3-: a theoretical investigation | 期刊论文 | Chen, Yishan|Pan, Xulin|Yan, He|Tan, Ninghua| |
| 21 | Terpene and lignan glycosides from the twigs and leaves of an endangered conifer, Cathaya argyrophylla | 期刊论文 | He, Wen-Jun|Fu, Zhao-Hui|Zeng, Guang-Zhi|Zhang, Yu-Mei|Han, Hong-Jin|Yan, He|Ji, Chang-Jiu|Chu, Hong-Biao|Tan, Ning-Hua| |
| 22 | Antimicrobial, Cytotoxic Lignans and Terpenoids from the Twigs of Pseudolarix kaempferi | 期刊论文 | He, Wen-Jun|Chu, Hong-Biao|Zhang, Yu-Mei|Han, Hong-Jin|Yan, He|Zeng, Guang-Zhi|Fu, Zhao-Hui|Olubanke, Ogunlana|Tan, Ning-Hua| |
| 23 | 一些重要天然活性环肽化学和生物活性研究进展 | 期刊论文 | 许文彦|赵思蒙|曾广智|贺文军|徐会敏|谭宁华| |
| 24 | Cytotoxic sesquiterpenes and lignans from Saussurea deltoidea | 期刊论文 | Xu, Jun-Ju|Huang, Huo-Qiang|Zeng, Guang-Zhi|Tan, Ning-Hua| |
| 25 | Triterpenoids and phenolic compounds from Croton macrostachyus | 期刊论文 | Michel F. Tala|Ning-Hua Tan|Blanche L. Ndontsa|Pierre Tane| |
| 26 | Cyclopeptide Alkaloids from Ziziphus apetala | 期刊论文 | Tan, Ning-Hua|Ji, Chang-Jiu|He, Wen-Jun|Shen, Yu|Leng, Ying|Xu, Wen-Yan|Fan, Jun-Ting|Zeng, Guang-Zhi|Kong, Ling-Dong| |
| 27 | Cyclopeptide RA-V inhibits angiogenesis by down-regulating ERK1/2 phosphorylation in HUVEC and HMEC-1 endothelial cells | 期刊论文 | Yue, Grace G. L.|Fan, Jun-Ting|Lee, Julia K. M.|Zeng, Guang-Zhi|Ho, Tina W. F.|Fung, Kwok-Pui|Leung, Ping-Chung|Tan, Ning-Hua|Lau, Clara B. S.| |
| 28 | Eremophilane-type sesquiterpenes from Alpinia oxyphylla with inhibitory activity against nitric oxide production | 期刊论文 | Xu, Junju|Su, Jia|Li, Yan|Tan, Ninghua| |
| 29 | Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases | 期刊论文 | Xu, Wenyan|Li, Liling|Du, Liangcheng|Tan, Ninghua| |
| 30 | 中药茺蔚子中一个新C-28降三萜 | 期刊论文 | 郑玉清|闫合|韩婧|谭宁华| |
| 31 | A New Cytotoxic Carbazole Alkaloid and Two New Other Alkaloids from Clausena excavata | 期刊论文 | Peng, Wen-Wen|Zeng, Guang-Zhi|Song, Wei-Wu|Tan, Ning-Hua| |
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