基于线粒体功能的人参核心功效物质基础与作用机制研究
U19A2013
2019
H3203.中药药效物质
赵大庆
联合基金项目
研究员
长春中医药大学
247万元
人参;作用机制;线粒体功能;药效物质;构效关系
2020-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Ginsenoside Rd attenuates ACTH-induced corticosterone secretion by blocking the MC2R-cAMP/PKA/CREB pathway in Y1 mouse adrenocortical cells | 期刊论文 | Wenqi Jin;Rui Ma;Lu Zhai;Xiaohao Xu;Tingting Lou;Qingxia Huang;Jing Wang;Daqing Zhao;Xiangyan Li;Liwei Sun |
| 2 | Gut Microbiota: Therapeutic Targets of Ginseng Against Multiple Disorders and Ginsenoside Transformation | 期刊论文 | Chen Zhaoqiang;Zhang Zepeng;Liu Jiaqi;Qi Hongyu;Li Jing;Chen Jinjin;Huang Qingxia;Liu Qing;Mi Jia;Li Xiangyan |
| 3 | Panax ginseng clinical trials: Current status and future perspectives | 期刊论文 | Shasha Fan;Zepeng Zhang;Hang Su;Peng Xu;Hongyu Qi;Daqing Zhao;Xiangyan Li |
| 4 | 20(S)-ginsenoside Rg3 promotes myoblast differentiation and protects against myotube atrophy via regulation of the Akt/mTOR/FoxO3 pathway | 期刊论文 | Manying Wang;Jixiang Ren;Xuenan Chen;Jianzeng Liu;Xiaohao Xu;Xiangyan Li;Daqing Zhao;Liwei Sun |
| 5 | Ginsenoside compound K protects against cerebral ischemia/reperfusion injury via Mul1/Mfn2-mediated mitochondrial dynamics and bioenergy | 期刊论文 | Qingxia Huang;Jing Li;Jinjin Chen;Zepeng Zhang;Peng Xu;Hongyu Qi;Zhaoqiang Chen;Jiaqi Liu;Jing Lu;Mengqi Shi;Yibin Zhang;Ying Ma;Daqing Zhao;Xiangyan Li |
| 6 | Neuroprotective Potentials of Panax Ginseng Against Alzheimer’s Disease: A Review of Preclinical and Clinical Evidences | 期刊论文 | Jing Li;Qingxia Huang;Jinjin Chen;Hongyu Qi;Jiaqi Liu;Zhaoqiang Chen;Daqing Zhao;Zeyu Wang;Xiangyan Li |
| 7 | Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons | 期刊论文 | Qingxia Huang;Tingting Lou;Jing Lu;Manying Wang;Xuenan Chen;Linyuan Xue;Xiaolei Tang;Wenxiu Qi;Zepeng Zhang;Hang Su;Wenqi Jin;Chenxu Jing;Daqing Zhao;Liwei Sun;Xiangyan Li |
| 8 | A SIRT1 Activator, Ginsenoside Rc, Promotes Energy Metabolism in Cardiomyocytes and Neurons | 期刊论文 | Qingxia Huang;Hang Su;Bin Qi;Ying Wang;Kaili Yan;Xinglin Wang;Xiangyan Li;Daqing Zhao |
| 9 | 人参“大补元气”功效机制研究及高附加值产品开发 | 奖励 | 李香艳;魏琨;王继岚;王泽玉;黄清霞;张泽鹏;于士婷;齐文秀;娄婷婷;王菁;苏航 |
| 10 | 人参二醇组皂苷和三醇组皂苷对血虚模型大鼠的治疗作用 | 期刊论文 | 张兰曹;梁祖国;张玉尧;张旭;张鹤 |
| 11 | Ginsenoside Rb2 inhibits p300-mediated SF3A2 acetylation at lysine 10 to promote Fscn1 alternative splicing against myocardial ischemic/ reperfusion injury | 期刊论文 | Huang Qingxia;Yao Yao;Wang Yisa;Li Jing;Chen Jinjin;Wu Mingxia;Guo Chen;Lou Jia;Yang Wenzhi;Zhao Linhua;Tong Xiaolin;Zhao Daqing;Li Xiangyan |
| 12 | 人参核心功效机制研究及产品创制 | 奖励 | 孙立伟;姜锐;麻锐;刘建增;陈雪楠;王曼莹;徐晓浩;闫秀慈;靳雯棋;王晶;黄清霞;景晨旭;翟璐 |
| 13 | Biotransformation, Pharmacokinetics, and Pharmacological Activities of Ginsenoside Rd Against Multiple Diseases | 期刊论文 | Jing Li;Qingxia Huang;Yao Yao;Peng Ji;E. Mingyao;Jinjin Chen;Zichen Zhang;Hongyu Qi;Jiaqi Liu;Zhaoqiang Chen;Daqing Zhao;Lei Zhou;Xiangyan Li |
| 14 | Pharmacological properties, molecular mechanisms and therapeutic potential of ginsenoside Rg3 as an antioxidant and anti-inflammatory agent | 期刊论文 | Wang Jing;Zeng Li;Zhang Ying;Qi Wenxiu;Wang Ziyuan;Tian Lin;Zhao Daqing;Wu Qibiao;Li Xiangyan;Wang Tan |
| 15 | Prevention effect of total ginsenosides and ginseng extract from Panax ginseng on cyclophosphamide-induced immunosuppression in mice | 期刊论文 | Zhang He;Sun Yue;Fan Meiling;Zhang Yuyao;Liang Zuguo;Zhang Lancao;Gao Xiang;He Xinzhu;Li Xiangyan;Zhao Daqing;Sagratini Gianni;Su Hang;Qi Wenxiu |
| 16 | Review of ginsenosides targeting mitochondrial function to treat multiple disorders: Current status and perspectives | 期刊论文 | Qingxia Huang;Song Gao;Daqing Zhao;Xiangyan Li |
| 17 | 人参组培不定根蛋白对小鼠的抗疲劳作用及其机制 | 期刊论文 | 王曼莹;付宝玉;徐晓浩;李香竹;陈红;孙立伟;赵大庆 |
| 18 | Targeting Sirtuin 1 signaling pathway by ginsenosides | 期刊论文 | Tingting Lou;Qingxia Huang;Hang Su;Daqing Zhao;Xiangyan Li |
| 19 | Compound K inhibits autophagy-mediated apoptosis induced by oxygen and glucose deprivation/reperfusion via regulating AMPK-mTOR pathway in neurons | 期刊论文 | Qingxia Huang;Tingting Lou;Manying Wang;Linyuan Xue;Jing Lu;He Zhang;Zepeng Zhang;Hui Wang;Chenxu Jing;Daqing Zhao;Liwei Sun;Xiangyan Li |
| 20 | 人参调控线粒体稳态抗心肌缺血再灌注损伤的研究进展 | 期刊论文 | 黄清霞;高嵩;赵大庆;李香艳 |
| 21 | 20(s)-ginseonside-Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone-injured C2C12 myotube-based model of skeletal atrophy in vitro | 期刊论文 | Wang Manying;Jiang Rui;Liu Jianzeng;Xu Xiaohao;Sun Guang;Zhao Daqing;Sun Liwei |
| 22 | Comparisons of Isolation Methods, Structural Features, and Bioactivities of the Polysaccharides from Three Common Panax Species: A Review of Recent Progress | 期刊论文 | Hongyu Qi;Zepeng Zhang;Jiaqi Liu;Zhaoqiang Chen;Qingxia Huang;Jing Li;Jinjin Chen;Mingxing Wang;Daqing Zhao;Zeyu Wang;Xiangyan Li |
| 23 | Ginseng in vascular dysfunction: A review of therapeutic potentials and molecular mechanisms | 期刊论文 | Zhang He;Hu Cheng;Xue Jiaojiao;Jin Di;Tian Lulu;Zhao Daqing;Li Xiangyan;Qi Wenxiu |
| 24 | Herbal/Natural Compounds Resist Hallmarks of Brain Aging: From Molecular Mechanisms to Therapeutic Strategies | 期刊论文 | Qiao Juhui;Wang Chenxi;Chen Yu;Yu Shuang;Liu Ying;Yu Shiting;Jiang Leilei;Jin Chenrong;Wang Xinran;Zhang Peiguang;Zhao Daqing;Wang Jiawen;Liu Meichen |
| 25 | Ginseng-derived nanoparticles alleviate inflammatory bowel disease via the TLR4/MAPK and p62/Nrf2/Keap1 pathways | 期刊论文 | Yang Song;Li Wenjing;Bai Xueyuan;Di Nunzio Giada;Fan Liangliang;Zhao Yueming;Ren Limei;Zhao Ronghua;Bian Shuai;Liu Meichen;Wei Yuchi;Zhao Daqing;Wang Jiawen |
查看更多信息请先登录或注册
