AMPK信号通路调控多巴胺能神经元的活化介导抑郁症的发生

81871068
2018
H1007.心境障碍
陈晓春
面上项目
教授
福建医科大学
61万元
ATP敏感的钾离子通道;抑郁症;多巴胺能神经元;脑源性神经营养因子;AMP激活的蛋白激酶
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Increased Notch2/NF-κB Signaling May Mediate the Depression Susceptibility: Evidence from Chronic Social Defeat Stress Mice and WKY Rats 期刊论文 Liao J;Zeng G;Fang W;Huang W;Dai X;Ye Q;Zhang J;Chen X
2 Circuit-wide proteomics profiling reveals brain region-specific protein signatures in the male WKY rats with endogenous depression 期刊论文 Jiangfeng Liao;Xue Mi;Guirong Zeng;Yuanxiang;Xiaoman Dai;Qinyong Ye;Xiaochun Chen;Jing Zhang
3 三醋酸甘油酯在制备预防和治疗抑郁症药物中的用途 专利 张静;陈晓春;黄炜彬
4 ApoE4 increases susceptibility to stress-induced age-dependent depression-like behavior and cognitive impairment. 期刊论文 Jing Zhang;Lanyan Lin;Xiaoman Dai;Nai’an Xiao;Qinyong Ye;Xiaochun Chen
5 Acetate supplementation produces antidepressant-like effect via enhanced histone acetylation. 期刊论文 Weibin Huang;Wenming Hu;Lili Cai;Guirong Zeng;Wenting Fang;Xiaoman Dai;Qinyong Ye;Xiaochun Chen;Jing Zhang
6 Ganoderma Lucidum Triterpenoids Improve Maternal Separation-Induced Anxiety- and Depression-like Behaviors in Mice by Mitigating Inflammation in the Periphery and Brain. 期刊论文 Xue Mi;Gui-Rong Zeng;Jie-Qing Liu;Zhou-Song Luo;Ling Zhang;Xiao-Man Dai;Wen-Ting Fang;Jing Zhang;Xiao-Chun Chen
7 Metformin alleviates the depression-like behaviors of elderly apoE4 mice via improving glucose metabolism and mitochondrial biogenesis. 期刊论文 Yingbin Lin;Xiaoman Dai;Jing Zhang;Xiaochun Chen
8 APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline 期刊论文 Wenting Fang;Naian Xiao;Guirong Zeng;Daode Bi;Xiaoman Dai;Xue Mi;Qinyong Ye;Xiaochun Chen;Jing Zhang
9 Metformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation 期刊论文 Fang Wenting;Zhang Jing;Hong Luyan;Huang Weibin;Dai Xiaoman;Ye Qinyong;Chen Xiaochun
10 The Roles ofPeroxiredoxin 6 inBrain Diseases 期刊论文 Jiangfeng Liao;Yusi Zhang;Xiaochun Chen;Jing Zhang
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