运动训练经SIRT3增强OPA1活性促进脑缺血大鼠线粒体结构修复及功能恢复
81802225
2018
H2001.康复治疗与康复机制
陈鸿宾
青年科学基金项目
主治医师
福建医科大学
21万元
缺血性脑卒中;线粒体功能;运动训练;去乙酰化酶3;视神经萎缩症蛋白
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 第十六届福建青年科技奖 | 奖励 | 陈鸿宾 |
| 2 | A controlled study of the efficacy and safety of tandospirone citrate combined with escitalopram in the treatment of vascular depression: A pilot randomized controlled trial at a single-center in China | 期刊论文 | Hongbin Chen;Qianwen Lin;Ting Lin;Yongsen Lin;Xiaohui Lin;Ronghua Chen;Ling Luo;Feifei Lin;Yingchun Xiao |
| 3 | IL-10 produces a dual effect on OGD-induced neuronal apoptosis of cultured cortical neurons via the NF-κB pathway | 期刊论文 | Hongbin Chen;Wei Lin;Peiqiang Lin;Mouwei Zheng;Yongxing Lai;Manli Chen;Yixian Zhang;Jianhao Chen;Xiaohui Lin;Longzai Lin;Quan Lan;Qilin Yuan;Ronghua Chen;Xinhong Jiang;Yingchun Xiao;Nan Liu |
| 4 | Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function | 期刊论文 | Yongxing Lai;Peiqiang Lin;Manli Chen;Yixian Zhang;Jianhao Chen;Mouwei Zheng;Ji Liu;Houwei Du;Ronghua Chen;Xiaodong Pan;Nan Liu;Hongbin Chen |
| 5 | 基于康复训练的多学科疗法治疗缺血性脑血管病临床应用与基础研究 | 奖励 | 刘楠;陈鸿宾;张逸仙;李菁;江信宏 |
| 6 | Bone marrow-derived mesenchymal stem cells improve post-ischemia neurological function in rats via the PI3K/AKT/GSK-3β/CRMP-2 pathway | 期刊论文 | Xiaohui Lin;Hongbin Chen;Manli Chen;Ting Li;Yongxing Lai;Longzai Lin;Peiqiang Lin;Ji Liu;Yixian Zhang;Ronghua Chen;Houwei Du;Xinhong Jiang;Nan Liu |
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