DNA聚合酶zeta（Pol ζ）维持基因组稳定性的机制研究
31500657
2015
C0507.核酸生物化学
李建
青年科学基金项目
副教授
成都大学
20万元
修复机制;修复复合物;修复突变;DNA结合蛋白;双链断裂
2016-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Compound F779-0434 causes synthetic lethality in BRCA2-deficient cancer cells by disrupting RAD52–ssDNA association | 期刊论文 | Jian Li;Qianye Yang;Yang Zhang;Kejia Huang;Rong Sun;Qi Zhao |
| 2 | Chimeric Antigen Receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward | 期刊论文 | Jian Li;Wenwen Li;Kejia Huang;Yang Zhang;Gary Kupfer;Qi Zhao |
| 3 | L1198F Mutation Resensitizes Crizotinib to ALK by Altering the Conformation of Inhibitor and ATP Binding Sites | 期刊论文 | Li Jian;Sun Rong;Wu Yuehong;Song Mingzhu;Li Jia;Yang Qianye;Chen Xiaoyi;Bao Jinku;Zhao Qi |
| 4 | In Silico Screening Identifies a Novel Potential PARP1 Inhibitor Targeting Synthetic Lethality in Cancer Treatment | 期刊论文 | Li Jian;Zhou Nan;Cai Peiling;Bao Jinku |
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