基于人羊膜间充质干细胞向成骨、软骨细胞定向分化的真菌来源天然小分子诱导剂发现及调控机制

81660363
2016
H0604.骨、关节、软组织损伤与修复
肖建辉
地区科学基金项目
教授
遵义医科大学
37万元
成软骨分化;小分子化合物;作用机制;成骨分化;人羊膜间充质干细胞
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 人羊膜上皮细胞的临床前研究进展 期刊论文 田亚冰;刘如明;肖建辉
2 Cocktail of hyaluronic acid and human amniotic mesenchymal cells effectively repairs cartilage injuries in sodium iodoacetate-induced osteoarthritis rats 期刊论文 Wang Ai-Tong;Zhang Qing-Fang;Wang Nuo-Xin;Yu Chang-Yin;Liu Ru-Ming;Luo Yi;Zhao Yu-Jie;Xiao Jian-Hui
3 透明质酸促人羊膜干细胞增殖的方法及其应用 专利 肖建辉;钟建江;刘如明;孙仁刚;陈代雄
4 Hyaluronic acid promotes osteogenic differentiation of human amniotic mesenchymal stem cells through the TGF-β/Smad signaling pathway 期刊论文 Ling-Tao Zhang;Ru-Ming Liu;Yi Luo;Yu-Jie Zhao;Dai-Xiong Chen;Chang-Yin Yu;Jian-Hui Xiao
5 一种治疗骨性关节炎的制剂及治疗方法 专利 肖建辉;张清芳
6 天然小分子化合物诱导间充质干细胞向成骨分化的研究进展 期刊论文 王怡晴;刘如明;王诺鑫;肖建辉
7 Ganoderal A effectively induces the osteogenic differentiation of human amniotic mesenchymal stem cells via Wnt/β-catenin and BMPs/SMADs signaling pathways. 期刊论文 Wang Yi-Qing;Wang Nuo-Xin;Luo Yi;Yu Chang-Yin;Xiao Jian-Hui
8 Hyaluronic acid regulates fates and therapeutic effects of human amniotic mesenchymal stem cells 会议论文 Nuo-Xin Wang;Ru-Ming Liu;Yi Luo;Yan Xu;Jian-Hui Xiao
9 Glucose-lowering and hypolipidemic activities of polysaccharides from Cordyceps taii in streptozotocin-induced diabetic mice 期刊论文 Liu Ru-Ming;Dai Rong;Luo Yi;Xiao Jian-Hui
10 Effect of CD44 on differentiation of human amniotic mesenchymal stem cells into chondrocytes via ERK signaling pathway 期刊论文 Yan Xu;Yi‑Qing Wang;Ai‑Tong Wang;Chang‑Yin Yu;Yi Luo;Ru‑Ming Liu;Yu‑Jie Zhao;Jian‑Hui Xiao
11 Ganoderic acid D protects human amnion mesenchymal stem cells against oxidative stress-induced senescence through PERK/NRF2 signaling pathway 期刊论文 Xu Yan;Yuan Huan;Luo Yi;Zhao Yu-Jie;Xiao Jian-Hui
12 Osteoinductive effect of natural polyphenolic compound BDMC in human amniotic mesenchymal stem cells and their therapeutic efficacy against osteoporotic mouse model 会议论文 Jin-Xing Wei;Jian-Hui Xiao
13 Effects of hyaluronic acid on differentiation of human amniotic epithelial cells and cell-replacement therapy of type 1 diabetes mice 期刊论文 Yi Luo;Ya-Wei Cheng;Chang-Yin Yu;Ru-Ming Liu;Yu-Jie Zhao;Dai-Xiong Chen;Jian-Jiang Zhong;Jian-Hui Xiao
14 METHOD FOR RESISTING AGING AND ENHANCING STEM CHARACTERISTICS OF HUMAN MESENCHYMAL STEM CELLS 专利 Xiao Jianhui;Luo Yi;Zhong Jianjiang;Yu Changyin
15 RASL11B gene enhances hyaluronic acid-mediated chondrogenic differentiation in human amniotic mesenchymal stem cells via the activation of Sox9/ ERK/Smad signals 期刊论文 Luo Yi;Wang Ai-Tong;Zhang Qing-Fang;Liu Ru-Ming;Xiao Jian-Hui
16 人羊膜细胞的免疫调节作用 期刊论文 程亚伟;罗熠;王诺鑫;肖建辉
17 高速かつ効率的にインビトロ増幅ヒト間葉系幹細胞的方法および使用 专利 肖 建輝;羅 ゆう;鍾 建江;余昌胤
18 Triterpenoids LM synergistically promotes transforming growth factor β3-mediated chondrogenic differentiation of human amniotic mesenchymal stem cells through BMP/Smad and MAPK/ERK signaling pathways 会议论文 Qian-Yun Li;Jian-Hui Xiao
19 一种快速高效体外扩增人间充质干细胞的方法及应用 专利 肖建辉;罗熠;钟建江;余昌胤
20 抗ヒト間葉系幹細胞老化およびその幹細胞性特徴増強方法 专利 肖 建輝;羅 ゆう;鍾 建江;余昌胤
21 不同来源间充质干细胞在骨性关节炎及软骨缺损治疗中应用的研究进展 期刊论文 王艾彤;肖建辉
22 Improved production of jiangxienone in submerged fermentation of Cordyceps jiangxiensis under nitrogen deficiency 期刊论文 Jiang Lu-Xi;Han Li-Liang;Wang Hui-Ping;Xu Jun-Wei;Xiao Jian-Hui
23 Synergistic effects of human amniotic mesenchymal stem cells in combination with hyaluronic acid in the iodoacetate-induced articular cartilage injure rat model 会议论文 Zhang Qing-Fang;Wang Ai-Tong;Liu Ru-Ming;Xiao Jian-Hui
24 Hyaluronic acid ameliorates the proliferative ability of human amniotic epithelial cells through activation of TGF-β/BMP signaling 期刊论文 Tian Ya-Bing;Wang Nuo-Xin;Xu Yan;Yu Chang-Yin;Liu Ru-Ming;Luo Yi;Xiao Jian-Hui
25 一种抗人间充质干细胞衰老及增强其干性特征的方法及应用 专利 肖建辉;罗熠;钟建江;余昌胤
26 一种诱导人间充质干细胞向成骨细胞分化的方法与应用 专利 肖建辉;王怡晴
27 Pro-proliferation effect of hyaluronic acid on human amniotic epithelial cells involves TGF-β/BMP signaling pathway 会议论文 Wang Nuo-Xin;Tian Ya-Bin;Liu Ru-Ming;Xiao Jian-Hui
28 RAPID AND EFFICIENT METHOD FOR EXPANDING HUMAN MESENCHYMAL STEM CELLS IN VITRO AND APPLICATION THEREO 专利 Xiao Jianhui;Luo Yi;Zhong Jianjiang;Yu Changyin
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