| 1 |
人朊病毒病流行特征和脑损伤分子机理研究
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奖励 |
董小平;石琦;陈操;高晨;周伟;肖康;韩俊;张瑾;王晶;高利萍 |
| 2 |
Analysis of 12 Chinese Patients with Proline-to-Leucine Mutation at Codon 102-Associated Gerstmann-Straussler-Scheinker Disease
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期刊论文 |
Wang Jing;Xiao Kang;Zhou Wei;Shi Qi;Dong Xiao-Ping |
| 3 |
堤岸田鼠(Bank Vole)重组朊蛋白在RT-QuIC反应上的特点及其关键位点的作用探索
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期刊论文 |
丁涤非;肖康;马月;王晶;高晨;董小平;刘霞;石琦 |
| 4 |
Cerebrospinal Fluids from Patients with Five Common Genetic Prion Diseases in China Display Distinct Reactivities in the RT- QuIC Assays
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期刊论文 |
Hu Chao;Chen Cao;Chen Jia;Xiao Kang;Zhou Wei;Xia Ying;Yang Wei;Wang Lin;Shi Qi;Dong Xiao-Ping |
| 5 |
IP10, KC and M-CSF is Remarkably Increased in the Brains from the Various Strains of Experimental Mice Infected with Different Scrapie Agents
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期刊论文 |
Chen Jia;Chen Cao;Hu Chao;Liu Lian;Xia Ying;Wang Lin;Yang Wei;Wu Hai-Yan;Zhou Wei;Xiao Kang;Shi Qi;Wu Yuezhang;Chen Zhi-Bao;Dong Xiao-Ping |
| 6 |
2016年中国克–雅病监测网络病例特征分析
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期刊论文 |
肖康;周伟;王园;王晶;董小平;石琦 |
| 7 |
Stimulations of the Culture Medium of Activated Microglia and TNF-Alpha on a Scrapie-Infected Cell Line Decrease the Cell Viability and Induce Marked Necroptosis That Also Occurs in the Brains from the Patients of Human Prion Diseases
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期刊论文 |
Ma Yue;Shi Qi;Xiao Kang;Wang Jing;Chen Cao;Gao Li-Ping;Gao Chen;Dong Xiao-Ping |
| 8 |
Generation and characterization of two strains of transgene mice expressing chimeric MiniSOG-MusPrP
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期刊论文 |
Gao Li-Ping;Wu Yue-Zhang;Xiao Kang;Yang Xue-Hua;Chen Dong-Dong;Shi Qi;Dong Xiao-Ping |
| 9 |
Comparative proteomics analyses for 139A and ME7 scrapie infected mice brains in the middle and terminal stages
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期刊论文 |
Shi Qi;Chen Li-Na;Lv Yan;Zhang Bao-Yun;Xiao Kang;Zhou Wei;Chen Cao;Sun Jing;Yang Xiao-Dong;Dong Xiao-Ping |
| 10 |
Different post-mortem brain regions from three Chinese FFI patients induce different reactive profiles both in the first and second generation RT-QuIC assays
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期刊论文 |
Xiao Kang;Shi Qi;Zhou Wei;Dong Xiao-Ping |
| 11 |
我国人朊病毒病疾病特征和朊病毒致中枢神经损伤机理研究
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奖励 |
董小平;石琦;陈操;高晨;周伟;韩俊;肖康;张瑾;王晶;王吉春 |
| 12 |
线粒体靶向抗氧化剂Mitoquinone和积雪草酸对朊病毒感染的神经细胞的治疗作用研究
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期刊论文 |
阿达莱提·买买提明;武月章;谢姆斯耶·吾拉音;胡超;陈嘉;周冬花;肖康;董小平;石琦 |
| 13 |
Characteristics of Chinese patients with genetic CJD who have E196A or E196K mutation in PRNP: comparative analysis of patients identified in the Chinese National CJD Surveillance System
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期刊论文 |
Shi Qi;Xiao Kang;Chen Cao;Zhou Wei;Gao Li-Ping;Wu Yue-Zhang;Wang Yuan;Hu Chao;Gao Chen;Dong Xiao-Ping |
| 14 |
Aberrant Alterations of Mitochondrial Factors Drp1 and Opa1 in the Brains of Scrapie Experiment Rodents
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期刊论文 |
Yang Xiao-Dong;Shi Qi;Sun Jing;Lv Yan;Ma Yue;Chen Cao;Xiao Kang;Zhou Wei;Dong Xiao-Ping |
| 15 |
Aberrant alterations of the expressions and S-nitrosylation of calmodulin and the downstream factors in the brains of the rodents during scrapie infection
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期刊论文 |
Zhang Ren-Qing;Chen Cao;Xiao Li-Jie;Sun Jing;Ma Yue;Yang Xiao-Dong;Xu Xiao-Feng;Xiao Kang;Shi Qi;Chen Zhi-Bao;Dong Xiao-Ping |
| 16 |
SMB-S15细胞中朊病毒PMCA方法的建立及对白藜芦醇抗朊病毒作用的评价
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期刊论文 |
周冬花;王晶;肖康;武月章;石琦;董小平 |
| 17 |
Rare genetic Creutzfeldt-Jakob disease with T188K mutation: analysis of clinical, genetic and laboratory features of 30 Chinese patients
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期刊论文 |
Shi Qi;Zhou Wei;Chen Cao;Xiao Kang;Wang Yuan;Gao Chen;Dong Xiao-Ping |
| 18 |
羊瘙痒因子139A感染引起小鼠脑组织中的α1-ACT表达增加
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期刊论文 |
徐小峰;张仁庆;马月;吕燕;黎建乐;石强;肖康;孙静;杨晓东;董小平;陈操 |
| 19 |
Stilbene Compounds Inhibit the Replications of Various Strains of Prions in the Levels of Cell Culture, PMCA, and RT-QuIC Possibly via Molecular Binding
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期刊论文 |
Zhou Dong-Hua;Wang Jing;Xiao Kang;Wu Yue-Zhang;Maimaitiming Adalaiti;Hu Chao;Gao Li-Ping;Chen Jia;Gao Chen;Chen Cao;Shi Qi;Dong Xiao-Ping |
| 20 |
青藏高原藏羚羊朊蛋白基因及氨基酸序列分析
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期刊论文 |
伍晶星;高利萍;陈冬冬;肖康;武月章;董小平;石琦 |
| 21 |
2018年中国克–雅病监测网络病例特征分析
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期刊论文 |
肖康;周伟;王园;董小平;石琦 |
| 22 |
Clinical and laboratory features of 14 young Chinese probable sCJD patients
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期刊论文 |
Shi Qi;Xiao Kang;Chen Cao;Zhou Wei;Gao Chen;Wang Jing;Zhang Bao-Yun;Wang Yuan;Dong Xiao-Ping |
| 23 |
Calmodulin level is significantly increased in the cerebrospinal fluid of patients with sporadic Creutzfeldt-Jakob disease
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期刊论文 |
Chen Cao;Hu Chao;Zhou Wei;Chen Jia;Shi Qi;Xiao Kang;Wang Yuan;Dong Xiao-Ping |
| 24 |
2020年中国克-雅病监测网络病例特征分析
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期刊论文 |
高利萍;肖康;周伟;王园;董小平;石琦 |
| 25 |
Enhanced Mitophagy Activity in Prion-Infected,Cultured Cells and Prion-Infected Experimental Mice via a Pinkl/Parkin-Dependent Mitophagy Pathway
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期刊论文 |
Gao Li-Ping;Xiao Kang;Wu Yue-Zhang;Chen Dong-Dong;Yang Xue-Hua;Shi Qi;Dong Xiao-Ping |
| 26 |
Redox induces diverse effects on recombinant human wild-type PrP and mutated PrP with inserted or deleted octarepeats
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期刊论文 |
Shi Qi;Chen Cao;Zhang Bao-Yun;Zhou Wei;Xiao Kang;Dong Xiao-Ping |
| 27 |
Evaluation of the effect of various main elements on the PrPSc detection by real-time quaking-induced conversion assay
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期刊论文 |
Xiao Kang;Shi Qi;Zhou Wei;Gao Chen;Chen Cao;Zhang Bao-Yun;Wang Jing;Dong Xiao-Ping |
| 28 |
Analysis of the Electrophoretic Profiles of Prion Protein in Carcinous and Pericarcinous Lysates of Six Different Types of Cancers
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期刊论文 |
Wei Wei;Wu Yue Zhang;Xiao Kang;Xu Guo Hui;Song Yun Tao;Shi Qi;Dong Xiao Ping |
| 29 |
Therapeutic implications of prion diseases
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期刊论文 |
Chen Cao;Dong Xiaoping |
| 30 |
Aberrant Decrease of the Endogenous SIRT3 and Increases of Acetylated Proteins in Scrapie-Infected Cell Line SMB-S15 and in the Brains of Experimental Mice
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期刊论文 |
Maimaitiming Adalaiti;Xiao Kang;Hu Chao;Chen Jia;Yang Xue-Hua;Zhou Dong-Hua;Gao Li-Ping;Dong Xiao-Ping;Shi Qi |
| 31 |
The low levels of nerve growth factor and its upstream regulatory kinases in prion infection is reversed by resveratrol
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期刊论文 |
Hu Chao;Chen Cao;Chen Jia;Xiao Kang;Wang Jing;Shi Qi;Ma Yue;Gao Li-Ping;Wu Yue-Zhang;Liu Lian;Xia Ying;Yan Pu;Adalati Maimaitiming;Zhou Dong-Hua;Zhang Li-Na;Chen Zhi-Bao;Dong Xiao-Ping |
| 32 |
Preparation of PrP-specific Polyclonal Antibody via Immunization of PRNP-knockout Mice with Recombinant Human PrP Protein
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期刊论文 |
Yang Xue Hua;Wu Yue Zhang;Xiao Kang;Gao Li Ping;Chen Dong Dong;Dong Xiao Ping;Shi Qi |
| 33 |
Cloning and analysis of PRNP gene of Vulpes corsac in Qinghai plateau, China
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期刊论文 |
Yang Xue-Hua;Xiao Kang;Wu Yuezhang;Gao Liping;Chen Dongdong;Dong Xiao-Ping;Shi Qi |
| 34 |
Decrease of RyR2 in the prion infected cell line and in the brains of the scrapie infected mice models and the patients of human prion diseases
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期刊论文 |
Shi Qi;Li Jian-Le;Ma Yue;Gao Li-Ping;Xiao Kang;Wang Jing;Zhou Wei;Chen Cao;Guo Yan-Jun;Dong Xiao-Ping |
| 35 |
Genetic Prion Disease: Insight from the Features and Experience of China National Surveillance for Creutzfeldt-Jakob Disease
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期刊论文 |
Shi Qi;Chen Cao;Xiao Kang;Zhou Wei;Gao Li-Ping;Chen Dong-Dong;Wu Yue-Zhang;Wang Yuan;Hu Chao;Gao Chen;Dong Xiao-Ping |
| 36 |
Impact of COVID-19 Pandemic on Patients With Neurodegenerative Diseases
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期刊论文 |
Hu Chao;Chen Cao;Dong Xiao-Ping |
| 37 |
A Chinese patient with the clinical features of Parkinson's disease contains a single copy of octarepeat deletion in PRNP case report
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期刊论文 |
Shi Qi;Shen Xiao-Jing;Gao Li-Ping;Xiao Kang;Zhou Wei;Wang Yuan;Chen Cao;Dong Xiao-Ping |
| 38 |
Profiles of 14-3-3 and Total Tau in CSF Samples of Chinese Patients of Different Genetic Prion Diseases
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期刊论文 |
Chen Cao;Hu Chao;Shi Qi;Zhou Wei;Mao Kang;Wang Yuan;Liu Lian;Chen Jia;Xia Ying;Dong Xiao-Ping |
| 39 |
核转录因子-κB(p65)在羊瘙痒因子139A感染小鼠脑组织中变化的研究
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期刊论文 |
马月;高利萍;肖康;王晶;董小平;石琦 |
| 40 |
A Chinese patient of P102L Gerstmann-Straussler-Scheinker disease contains three other disease-associated mutations in SYNE1
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期刊论文 |
Wang Jing;Xiao Kang;Zhou Wei;Gao Chen;Chen Cao;Shi Qi;Dong Xiao-Ping |
| 41 |
The genetic Creutzfeldt-Jakob disease with E200K mutation: analysis of clinical, genetic and laboratory features of 30 Chinese patients
|
期刊论文 |
Gao Li-Ping;Shi Qi;Xiao Kang;Wang Jing;Zhou Wei;Chen Cao;Dong Xiao-Ping |
| 42 |
Reduction of NF-kappa B (p65) in Scrapie-Infected Cultured Cells and in the Brains of Scrapie-Infected Rodents
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期刊论文 |
Ma Yue;Shi Qi;Wang Jing;Xiao Kang;Sun Jing;Lv Yan;Guo Man;Zhou Wei;Chen Cao;Gao Chen;Zhang Bao-Yun;Dong Xiao-Ping |
| 43 |
Alternative complement pathway is activated in the brains of scrapie-infected rodents
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期刊论文 |
Chen Cao;Lv Yan;Hu Chao;Xu Xiao-Feng;Zhang Ren-Qing;Xiao Kang;Ma Yue;Gao Li-Ping;Li Jian-Le;Shi Qiang;Wang Jing;Shi Qi;Dong Xiao-Ping |
| 44 |
MiniSOG蛋白的单克隆抗体制备及初步研究
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期刊论文 |
高利萍;武月章;杨雪花;陈冬冬;肖康;董小平;石琦 |
| 45 |
朊病毒感染中钙调蛋白相关激酶含量异常变化的研究
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期刊论文 |
胡超;王耀恩;陈嘉;高利萍;郭海婷;严普;刘恋;肖康;王晶;石琦;董小平;陈志宝;陈操 |
| 46 |
Accumulation of Prion and Abnormal Prion Protein Induces Hyperphosphorylation of α‐Synuclein in the Brain Tissues from Prion Diseases and in the Cultured Cells
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期刊论文 |
Chen Dong-Dong;Gao Li-Ping;Wu Yue-Zhang;Chen Jia;Hu Chao;Xiao Kang;Chen Cao;Shi Qi;Dong Xiao-Ping |
| 47 |
T188K-Familial Creutzfeldt-Jacob Disease, Predominant Among Chinese, has a Reactive Pattern in CSF RT-QuIC Different from D178N-Fatal Familial Insomnia and E200K-Familial CJD
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期刊论文 |
Xiao Kang;Shi Qi;Zhou Wei;Zhang Bao-Yun;Wang Yuan;Chen Cao;Ma Yue;Gao Chen;Dong Xiao-Ping |
| 48 |
The associations of two SNPs in miRNA-146a and one SNP in ZBTB38-RASA2 with the disease susceptibility and the clinical features of the Chinese patients of sCJD and FFI
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期刊论文 |
Gao Chen;Shi Qiang;Wei Jing;Zhou Wei;Xiao Kang;Wang Jing;Shi Qi;Dong Xiao-Ping |
| 49 |
青藏高原岩羊朊蛋白基因及氨基酸序列分析
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期刊论文 |
伍晶星;高利萍;陈冬冬;肖康;武月章;董小平;石琦 |
| 50 |
Remarkable increases of 1-antichymotrypsin in brain tissues of rodents during prion infection
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期刊论文 |
Chen Cao;Xu Xiao-Feng;Zhang Ren-Qing;Ma Yue;Lv Yan;Li Jian-Le;Shi Qiang;Xiao Kang;Sun Jing;Yang Xiao-Dong;Shi Qi;Dong Xiao-Ping |
