端粒DNA四重折叠结构在端粒DNA复制中的作用

30970617
2009
C0509.生物学过程与代谢
谭铮
面上项目
教授
中国科学院动物研究所
32万元
四重折叠结构;染色体;DNA;端粒DNA末端复制;端粒
2010-01-01到2012-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Contribution of Telomere G-Quadruplex Stabilization to the Inhibition of Telomerase-Mediated Telomere Extension by Chemical Ligands 期刊论文 C. Y. Chen|Q. Wang|J. Q. Liu|Y. H. Hao|Z. Tan|
2 Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNA 期刊论文 Zheng, Ke-wei|Chen, Zhao|Hao, Yu-hua|Tan, Zheng|
3 G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Unwinding Study and Comparison with Duplex Substrates 期刊论文 J. Q. Liu|C. Y. Chen|Y. Xue|Y. H. Hao|Z. Tan|
4 Telomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells 期刊论文 F. Wang|M. L. Tang|Z. X. Zeng|R. Y. Wu|Y. Xue|Y. H. Hao|D. W. Pang|Y. Zhao|Z. Tan|
5 Folding Equilibrium Constants of Telomere G-Quadruplexes in Free State or Associated with Proteins Determined by Isothermal Differential Hybridization 期刊论文 Wang, Quan|Ma, Li|Hao, Yu-hua|Tan, Zheng|
6 Kinetic and Thermodynamic Control of G-Quadruplex Folding 期刊论文 Y. Xue|J. Q. Liu|K. W. Zheng|Z. Y. Kan|Y. H. Hao|Z. Tan|
7 G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase 期刊论文 Q. Wang|J. Q. Liu|Z. Chen|K. W. Zheng|C. Y. Chen|Y. H. Hao|Z. Tan|
8 Dissecting the strand folding orientation and formation of G-quadruplexes in single- and double-stranded nucleic acids by ligand-induced photocleavage footprinting 期刊论文 K. W. Zheng|D. Zhang|L. X. Zhang|Y. H. Hao|X. Zhou|Z. Tan|
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