全氟化合物毒性作用新靶点蛋白质酪氨酸磷酸酶的识别及分子机制研究

21577163
2015
B0607.环境毒理与健康
杨郁
面上项目
副研究员
中国科学院生态环境研究中心
65万元
识别;致毒机制;全氟化合物;生物大分子;生物效应
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 一种用于蛋白质O-GlcNAc糖基转移酶活性的免标记电化学传感检测方法 专利 杨郁;郭良宏;任肖敏;万斌;谷玉新
2 Length effects on the dynamic process of cellular uptake and exocytosis of single-walled carbon nanotubes in murine macrophage cells 期刊论文 Xuejing Cui;Bin Wan;Yu Yang;Xiaomin Ren;Liang-Hong Guo
3 Optically Active Nanomaterials for Bioimaging and Targeted Therapy 期刊论文 Yu Yang;Li Wang;Bin Wan;Yuxin Gu;Xinxin Li
4 一种用于蛋白质酪氨酸磷酸酶活性的免标记电化学传感检测方法 专利 杨郁;郭良宏;任肖敏
5 一种荧光标记的全氟烷基酸探针及其应用 专利 任肖敏;曹林英;杨郁;郭良宏
6 Insight into the Mechanisms of Combined Toxicity of Single-Walled Carbon Nanotubes and Nickel Ions in Macrophages: Role of P2X7 Receptor 期刊论文 Xuejing Cui;Bin Wan;Liang-Hong Guo;Yu Yang;Xiaomin Ren
7 Carbon Nanomaterials Stimulate HMGB1 Release From Macrophages and Induce Cell Migration and Invasion 期刊论文 Xuejing Cui;Bin Wan;Yu Yang;Yan Xin;Yi-Chun Xie;Liang-Hong Guo;Lin L. Mantell
8 Inhibition of O-linked N-acetylglucosamine transferase activity in PC12 cells - A molecular mechanism of organophosphate flame retardants developmental neurotoxicity 期刊论文 Yuxin Gu;Yu Yang;Bin Wan;Minjie Li;Liang-Hong Guo
9 Arginine decarboxylase: A novel biological target of mercury compounds identified in PC12 cells 期刊论文 Sufang Wang;Qiyan Lv;Yu Yang;Liang-Hong Guo;Bin Wan;Xiaomin Ren;Hui Zhang
10 Identification of protein tyrosine phosphatase SHP-2 as a new target of perfluoroalkyl acids in HepG2 cells 期刊论文 Yu Yang;Qi-Yan Lv;Liang-Hong Guo;Bin Wan;Xiao-Min Ren;Ya-Li Shi;Ya-Qi Cai
11 New insights into mechanism of bisphenol analogue neurotoxicity: implications of inhibition of O‑GlcNAcase activity in PC12 cells 期刊论文 Yu-Xin Gu;Xiao-Xing Liang;Nuo-Ya Yin;Yu Yang;Bin Wan;Liang-Hong Guo;Francesco Faiola
12 Cytotoxicity and autophagy induction by graphene quantum dots with different functional groups 期刊论文 Yichun Xie;Bin Wan;Yu Yang;Xuejing Cui;Yan Xin;Liang-Hong Guo
13 一种检测待测样品与GPR40结合能力的方法及其专用特异荧光探针 专利 任肖敏;曹林英;杨郁;郭良宏
14 Hydroxylated Polybrominated Biphenyl Ethers Exert Estrogenic Effects via Non-Genomic G Protein–Coupled Estrogen Receptor Mediated Pathways 期刊论文 Lin-Ying Cao;Xiao-Min Ren;Yu Yang;Bin Wan;Liang-Hong Guo;De Chen;Yong Fan
15 Crucial Role of P2X7 Receptor in Regulating Exocytosis of Single-Walled Carbon Nanotubes in Macrophages 期刊论文 Xuejing Cui;Bin Wan;Yu Yang;Xiaomin Ren;Liang-Hong Guo;Hui Zhang
16 Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells 期刊论文 Yan Xin;Bin Wan;Yu Yang;Xue-Jing Cui;Yi-Chun Xie;Liang-Hong Guo
17 Label-free electrochemical biosensing of small-molecule inhibition on O-GlcNAc glycosylation 期刊论文 Yu Yang;Yuxin Gu;Bin Wan;Xiaomin Ren;Liang-Hong Guo
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