基于多中心磁共振影像组学的阿尔茨海默病早期诊断关键技术研究
81871438
2018
H2708.医学图像数据处理、分析与可视化
刘勇
面上项目
教授
北京邮电大学
57万元
影像组学;多中心;阿尔茨海默病;早期诊断;机器学习
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 中华医学科技奖, 二等奖, 项目名称:磁共振功能成像技术在重大脑疾病研究中的应用 | 奖励 | 于春水;朱朝喆;蒋田仔;秦文;刘勇;刘冰;张新卿;禚传军;张雪君;张敬;张宁男楠;姜琳;刘静纯 |
| 2 | Structural and functional connectivity abnormalities of the default mode network in patients with Alzheimer's disease and mild cognitive impairment within two independent datasets. | 期刊论文 | Zhou Bo;Dou Xuejiao;Wang Wei;Yao Hongxiang;Feng Feng;Wang Pan;Yang Zhengyi;An Ningyu;Liu Bing;Zhang Xi;Liu Yong |
| 3 | Altered Connection and Diagnosis Utility of White Matter in Alzheimer’s Disease: A Multi-site Automated Fiber Quantification Study | 会议论文 | Qu Yida;Wang Pan;Liu Bing;Kang Xiaopeng;Chen Pindong;Du Kai;Liu Yong |
| 4 | Aberrant Hippocampal Functional Connectivity Is Associated with Fornix White Matter Integrity in Alzheimer's Disease and Mild Cognitive Impairment | 期刊论文 | Wang Pan;Zhou Bo;Yao Hongxiang;Sangma Xie;Feng Feng;Zhang Zengqiang;Guo Yan'e;An Ningyu;Zhou Yuying;Zhang Xi;Liu Yong |
| 5 | Characterizing white matter connectivity in Alzheimer’s disease and mild cognitive impairment: An automated fiber quantification analysis with two independent datasets | 期刊论文 | Dou Xuejiao;Yao Hongxiang;Feng Feng;Wang Pan;Zhou Bo;Jin Dan;Yang Zhengyi;Li Jin;Zhao Cui;Wang Luning;An Ningyu;Liu Bing;Zhang Xi;Liu Yong |
| 6 | Impaired time-distance reconfiguration patterns in Alzheimer's disease: a dynamic functional connectivity study with 809 individuals from 7 sites | 期刊论文 | Du Kai;Chen Pindong;Zhao Kun;Qu Yida;Kang Xiaopeng;Liu Yong;Multi-center Alzheimer Disease Imaging Consortium |
| 7 | Sex modulates the apolipoprotein E e4 effect on white matter and cortical functional connectivity in individuals with amnestic mild cognitive impairment | 期刊论文 | Lin Hua;Sun Yu;Li Muwei;Zhan Yang;Lin Li;Ding Zhaohua;Han Ying |
| 8 | 第一届全国博士后创新创业大赛总决赛揭榜领题赛金奖 | 奖励 | 刘勇;徐光远;张校雨;康孝鹏;孙一堡;吴江平;仲苏玉;聂礼强 |
| 9 | Generalizable, Reproducible, and Neuroscientifically Interpretable Imaging Biomarkers for Alzheimer's Disease | 期刊论文 | Jin Dan;Zhou Bo;Han Ying;Ren Jiaji;Han Tong;Liu Bing;Lu Jie;Song Chengyuan;Wang Pan;Wang Dawei;Xu Jian;Yang Zhengyi;Yao Hongxiang;Yu Chunshui;Zhao Kun;Wintermark Max;Zuo Nianming;Zhang Xinqing;Zhou Yuying;Zhang Xi;Jiang Tianzi;Wang Qing;Liu Yong |
| 10 | ASAF: altered spontaneous activity fingerprinting in Alzheimer's disease based on multisite fMRI | 期刊论文 | Li Jiachen;Jin Dan;Li Ang;Liu Bing;Song Chengyuan;Wang Pan;Wang Dawei;Xu Kaibin;Yang Hongwei;Yao Hongxiang;Zhou Bo;Bejanin Alexandre;Chetelat Gael;Han Tong;Lu Jie;Wang Qing;Yu Chunshui;Zhang Xinqing;Zhou Yuying;Zhang Xi;Jiang Tianzi;Liu Yong;Han Ying |
| 11 | Combined functional and structural imaging of brain white matter reveals stage-dependent impairment in multiple system atrophy of cerebellar type | 期刊论文 | Lin Hua;Lin Li;Xu Lyuan;Li Siran;Song Penghui;Li Muwei |
| 12 | 基于对抗神经网络的医学图像合成方法、分类方法及装置 | 专利 | 刘勇;金丹;蒋田仔;刘冰 |
| 13 | Cortical and subcortical grey matter abnormalities in white matter hyperintensities and subsequent cognitive impairment | 期刊论文 | Zhu Wenhao;Huang Hao;Yang Shiqi;Luo Xiang;Zhu Wenzhen;Meng Qi;Zuo Chengchao;Liu Yong;Wang Wei |
| 14 | Quantitative radiomic features as new biomarkers for Alzheimer’s disease: An amyloid PET study | 期刊论文 | Ding Yanghui;Zhao Kun;Che Tongtong;Du Kai;Sun Hongzan;Liu Shu;Zheng Yuanjie;Li Shuyu;Liu Bing;Liu Yong;ADNI |
| 15 | 吴文俊人工智能科学技术奖 | 奖励 | 蒋田仔;刘勇;刘冰;于春水;李坤成 |
| 16 | Regional Radiomics Similarity Networks Reveal Distinct Subtypes and Abnormality Patterns in Mild Cognitive Impairment | 期刊论文 | Zhao Kun;Zheng Qiang;Dyrba Martin;Rittman Timothy;Li Ang;Che Tongtong;Chen Pindong;Sun Yuqing;Kang Xiaopeng;Li Qiongling;Liu Bing;Liu Yong;Li Shuyu;ADNI |
| 17 | Four distinct subtypes of Alzheimer's disease based on resting-state connectivity biomarkers | 期刊论文 | Chen Pindong;Yao Hongxiang;Tijms Betty M.;Wang Pan;Wang Dawei;Song Chengyuan;Yang Hongwei;Zhang Zengqiang;Zhao Kun;Qu Yida;Kang Xiaopeng;Du Kai;Fan Lingzhong;Han Tong;Yu Chunshui;Zhang Xi;Jiang Tianzi;Zhou Yuying;Lu Jie;Han Ying;Liu Bing;Zhou Bo;Liu Yong;Alzheimer's Disease Neuroimaging Initiative |
| 18 | Multi-template Neuroimaging Feature Selection Using Weight-constrained Low-rank Learning for Alzheimer’s Disease Classification | 会议论文 | Hao Xiaoke;An Qijin;Jiang Tao;Guo Yingchun;Li Jie;Shi Shuo;Yu Ming;Liu Bing;Han Ying;Liu Yong |
| 19 | A systematic analysis of diagnostic performance for Alzheimer's disease using structural MRI | 期刊论文 | Wu Jiangping;Zhao Kun;Li Zhuangzhuang;Wang Dong;Ding Yanhui;Wei Yongbin;Zhang Han;Liu Yong |
| 20 | CHARACTERIZING WHITE MATTER CONNECTIVITY IN ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT: AUTOMATED FIBER QUANTIFICATION | 会议论文 | Dou Xuejiao;Yuo Hongxiang;Jin Dan;Feng Feng;Wung Pan;Zhou Bo;Liu Bing;Yang Zhengyi;An Ningyu;Zhang Xi;Liu Yong |
| 21 | Regional radiomics similarity networks (R2SNs) in the human brain: Reproducibility, small-world properties and a biological basis | 期刊论文 | Zhao Kun;Zheng Qiang;Che Tongtong;Dyrba Martin;Li Qiongling;Ding Yanhui;Zheng Yuanjie;Liu Yong;Li Shuyu |
| 22 | A Pathway-Specific Polygenic Risk Score is Associated with Tau Pathology and Cognitive Decline | 期刊论文 | Sun Yuqing;Wang Meng;Zhao Yuxin;Hu Ke;Liu Yong;Liu Bing |
| 23 | 基于注意力机制的脑疾病分类系统 | 专利 | 刘勇;金丹;蒋田仔;刘冰 |
| 24 | Grab-AD: Generalizability and reproducibility of altered brain activity and diagnostic classification in Alzheimer's Disease | 期刊论文 | Jin Dan;Wang Pan;Zalesky Andrew;Liu Bing;Song Chengyuan;Wang Dawei;Xu Kaibin;Yang Hongwei;Zhang Zengqiang;Yao Hongxiang;Zhou Bo;Han Tong;Zuo Nianming;Han Ying;Lu Jie;Wang Qing;Yu Chunshui;Zhang Xinqing;Zhang Xi;Jiang Tianzi;Zhou Yuying;Liu Yong |
| 25 | Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis | 期刊论文 | Zhao Kun;Ding Yanhui;Han Ying;Fan Yong;Alexander-Bloch Aaron;Han Tong;Jin Dan;Liu Bing;Lu Jie;Song Chengyuan;Wang Pan;Wang Dawei;Wang Qing;Xu Kaibin;Yang Hongwei;Yao Hongxiang;Zheng Yuanjie;Yu Chunshui;Zhou Bo;Zhang Xinqing;Zhou Yuying;Jiang Tianzi;Zhang Xi;Liu Yong |
| 26 | Coupling of the spatial distributions between sMRI and PET reveals the progression of Alzheimer’s disease | 期刊论文 | Zhao Kun;Lin Jiaji;Dyrba Martin;Wang Dong;Che Tongtong;Wu Haoyang;Wang Jingyu;Liu Yong;Li Shuyu |
| 27 | 中国国际“互联网+”大学生创新创业大赛北京赛区优秀创新创业导师 | 奖励 | 刘勇 |
| 28 | Identification of subjective cognitive decline due to Alzheimer’s disease using multimodal MRI combining with machine learning | 期刊论文 | Lin Hua;Jiang Jiehui;Li Zhuoyuan;Sheng Can;Du Wenying;Li Xiayu;Han Ying |
| 29 | Disrupted white matter functional connectivity in aMCI APOEε4 carriers: a resting-state study | 期刊论文 | Lin Hua;Li Muwei;Zhan Yang;Lin Li;Yang Kun;Hu Shimin;Han Ying |
| 30 | Attention-based 3D Convolutional Network for Alzheimer's Disease Diagnosis and Biomarkers Exploration | 会议论文 | Jin Dan;Xu Jian;Zhao Kun;Hu Fangzhou;Yang Zhengyi;Liu Bing;Jiang Tianzi;Liu Yong |
| 31 | AI4AD: Artificial intelligence analysis for Alzheimer's disease classification based on a multisite DTI database | 期刊论文 | Qu Yida;Wang Pan;Liu Bing;Song Chengyuan;Wang Daiwei;Yang Hongwei;Zhang Zengqiang;Chen Pindong;Kang Xiaopeng;Du Kai;Yao Hongxiang;Zhou Bo;Han Tong;Zuo Nianming;Han Ying;Lu Jie;Yu Chunshui;Zhang Xi;Jiang Tianzi;Zhou Yuying;Liu Yong;MCADI |
| 32 | 阿尔茨海默病风险评估模型建立的方法和电子设备 | 专利 | 刘勇 |
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