多胺微环境对 DKK1功能及肝癌、乳腺癌转移性能的影响

81573465
2015
H3505.抗肿瘤药物药理
谢松强
面上项目
教授
河南大学
54万元
肿瘤转移;肝癌;多胺微环境;DKK1;乳腺癌
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation 期刊论文 Xiaojuan Xu;Senzhen Wang;Yuan Chang;Chaochao Ge;Xinna Li;Yongli Feng;Songqiang Xie;Chaojie Wang;Fujun Dai;Wen Luo
2 Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells 期刊论文 Wang Cong;Ruan Ping;Zhao Ying;Li Xiaomeng;Wang Jun;Wu Xiaoxiao;Liu Tong;Wang Shasha;Hou Jiuzhou;Li Wei;Li Qian;Li Jinghua;Dai Fujun;Fang Dong;Wang Chaojie;Xie Songqiang
3 Akt1 inhibition promotes breast cancer metastasis through EGFR-mediated β-catenin nuclear accumulation 期刊论文 Li Wei;Hou Jiuzhou;Niu Jie;Xi Zhuoqing;Ma Chang;Sun Hua;Wang Chaojie;Fang Dong;Li Qin;Xie Songqiang
4 Design, Synthesis, and Biological Evaluation of Mitochondria-Targeted Flavone-Naphthalimide-Polyamine Conjugates with Antimetastatic Activity 期刊论文 Fujun Dai;Qian Li;Yuxia Wang;Chaochao Ge;Chenyang Feng;Songqiang Xie;Haoying He;Xiaojuan Xu;Chaojie Wang
5 Targeting p21-activated kinase 1 inhibits growth and metastasis via Raf1/MEK1/ERK signaling in esophageal squamous cell carcinoma cells 期刊论文 Liang Chen;Shuning Bi;Jiuzhou Hou;Zhijun Zhao;Chaojie Wang;Songqiang Xie
6 DKK1 inhibits breast cancer cell migration andinvasion throughsuppression ofβ-catenin/ MMP7 signaling pathway 期刊论文 Jie Niu;Xiao‑Meng Li;Xiao Wang;Chao Liang;Yi‑Dan Zhang;Hai‑Ying Li;Fan‑Ye Liu;Hua Sun;Song‑Qiang Xie;Dong Fang
7 Synthesis and biological evaluation of novel alkylated polyamine analogues as potential anticancer agents 期刊论文 Meng Li;Yuxia Wang;Chaochao Ge;Liping Chang;Chaojie Wang;ZhiyongTian;Senzhen Wang;Fujun Dai;Luyao Zhao;Songqiang Xie
8 Inhibition of PIKfyve using YM201636 suppresses the growth of liver cancer via the induction of autophagy 期刊论文 Jiu-Zhou Hou;Zhuo-Qing Xi;Jie Niu;Wei Li;Xiao Wang;Chao Liang;Hua Sun;Dong Fang;Song-Qiang Xie
9 Polyamine-Based Pt(IV) Prodrugs as Substrates for Polyamine Transporters Preferentially Accumulate in Cancer Metastases as DNA and Polyamine Metabolism Dual-Targeted Antimetastatic Agents 期刊论文 Hanfang Liu;Jing Ma;Yingguang Li;Kexin Yue;Linrong Li;Zhuoqing Xi;Xiao Zhang;Jianing Liu;Kai Feng;Qi Ma;Sitong Liu;Shudi Guo;Peng George Wang;Chaojie Wang;Songqiang Xie
10 Wee1 Inhibitor AZD1775 Effectively Inhibits the Malignant Phenotypes of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo 期刊论文 Shuning Bi;Qiu-Ren Wei;Zhijun Zhao;Liang Chen;Chaojie Wang;Song-Qiang Xie
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