帕金森病相关蛋白parkin对突触核蛋白降解的调控作用及其致病机制

81271410
2012
H0912.神经退行性变及相关疾病
魏建设
面上项目
教授
河南大学
70万元
线粒体;Parkin;突触核蛋白;细胞自噬;蛋白降解
2013-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The interaction of α-Synuclein and β-Synuclein in MPTP-induced PD mice 会议论文 Wei Nannan|Li Ping|Huang Tian|Wei Jianshe|
2 The cascade of oxidative stress and tau protein autophagic dysfunction in Alzheimer’s disease. 专著 Nannan Wei|Zhiquan Zhao|Huimin Liang|Jianshe Wei|
3 DJ-1 mutation modulates synuclein and enhances neurodegeneration in synucleinopathy 会议论文 Wei Nannan|Liang Huimin|Huang Tian|Wei Jianshe|
4 Gaucher-Associated Parkinsonism 期刊论文 Huimin Liang|Zhiquan Zhao|Makoto Hashimoto|Jianshe Wei|
5 ATP13A2is involved in the process of synucleinopathy related to dementia with Lewybodies 会议论文 Nan-Nan Wei|Wen-Jin Xia|Cong-Cong Li|Jian-She Wei|
6 Disease-causing mutations in parkin protein impair mitochondrial function and enhance neurodegeneration 会议论文 Wei Nannan|Li Ping|Huang Tian|Wei Jianshe|
7 b-synuclein reduction associated with α-Synuclein aggregation promotes autophagic cell death in chronic MPTP-induced PD mice 会议论文 Wang Yi|Wei Nannan|Li Ping|Huang Tian|
8 Disease-causing mutations in DJ-1 protein impair mitochondrial function and enhance neurodegeneration in synucleinopathy 会议论文 Zhao Zhiquan|Wei Nannan|Liang Huimin|Wei Jianshe|
9 Optogenetic stimulationameliorates depressive-like phenotype in V70M b-synuclein mouse model of Parkinson’s disease 会议论文 李聪聪|王萌萌|夏文瑾|赵智权|
10 PINK1 and Parkin Crosstalk Synucleinopathies by Mitophagy 会议论文 Nan-Nan Wei|Zhi-Quan Zhao|Wen-Jin Xia|Cong-Cong Li|
11 Parkin mutations impair mitochondrial function and enhance neurodegeneration in synucleinopathy associated with dementia with Lewy bodies. 会议论文 Ping Li|Huimin Liang|Masayo Fujita|Makato Hashimoto|
12 The ambiguous relationship of oxidative stress, tau hyperphosphorylation, and autophagy dysfunction in Alzheimer's disease 期刊论文 Xinying Ji|Wenwu Chen|Mengzhou Xue|Jianshe Wei|
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