靶向蓝藻FBP/SBPase 的新型选择性杀藻剂的设计合成及作用机制研究
21877046
2018
B0706.药物化学生物学
冯玲玲
面上项目
教授
华中师范大学
67万元
杀藻剂;作用机制;分子设计合成;蓝藻FBP/SBPase;分子探针
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Employing TosMIC as a C1N1 "Two-Atom Synthon" in Imidazole Synthesis by Neighboring Group Assistance Strategy | 期刊论文 | Xiao Geng;Can Wang;Chun Huang;Yang Bao;Peng Zhao;You Zhou;Yan-Dong Wu;Ling-ling Feng;An-Xin Wu |
| 2 | 蓝藻FBP/SBPase 的制备及其与配体相互作用的分析 | 期刊论文 | 冯玲玲;陈琼;李玉梦;梁景晗;王舟 |
| 3 | Discovery of novel allosteric site and covalent inhibitors of FBPase with potent hypoglycemic effects | 期刊论文 | Huang Yunyuan;Wei Lin;Han Xinya;Chen Haifeng;Ren Yanliang;Xu Yanhong;Song Rongrong;Rao Li;Su Chen;Peng Chao;Feng Lingling;Wan Jian |
| 4 | Identification of the New Covalent Allosteric Binding Site of Fructose-1,6-bisphosphatase with Disulfiram Derivatives toward Glucose Reduction | 期刊论文 | Yunyuan Huang;Yixiang Xu;Rongrong Song;Shuaishuai Ni;Jiaqi Liu;Yanhong Xu;Yanliang Ren;Li Rao;Yingjie Wang;Lin Wei;Lingling Feng;Chen Su;Chao Peng;Jian Li;Jian Wan |
| 5 | Strain-boosted hyperoxic graphene oxide efficiently loading and improving performances of microcystinase | 期刊论文 | Hong-Lin Liu;Cai Cheng;Ling-Zi Zuo;Ming-Yue Yan;Yan-Lin He;Shi Huang;Ming-Jing Ke;Xiao-Liang Guo;Yu Feng;Hai-Feng Qian;Ling-Ling Feng |
| 6 | Structure optimization and bioactivity evaluation of ThDP analogs targeting cyanobacterial pyruvate dehydrogenase E1 | 期刊论文 | Jiangtao Feng;Haifeng He;Yuan Zhou;Meng Cai;Hao Peng;Honglin Liu;Lei Liu;Lingling Feng;Hongwu He |
| 7 | Simultaneous Microcystin Degradation and Microcystis aeruginosa Inhibition with the Single Enzyme Microcystinase A | 期刊论文 | Honglin Liu;Xiaoliang Guo;Lei Liu;Mingyue Yan;Jiahui Li;Shuyan Hou;Jian Wan;Lingling Feng |
| 8 | 含硝基乙烯基的酯类化合物及其制备方法和应用 | 专利 | 万坚;韩新亚;陈海峰;黄运远;池波;任彦亮;冯玲玲;饶立 |
| 9 | 2,5-二(取代氨基甲酰基甲硫基)-1,3,4-噻二唑类化合物在抑制蓝藻生长中的应用 | 专利 | 冯玲玲;万坚;秦玉昌;韩强;赵晓晶;李俊;冯江涛 |
| 10 | 一种用于快速判断小分子结合人体肝脏果糖1,6-二磷酸酶底物位点或变构位点的方法 | 专利 | 万坚;黄运远;徐榕;韩新亚;肖闪;任彦亮;冯玲玲;饶立 |
| 11 | 一类腙类化合物在制备抗真菌药物中的应用 | 专利 | 万坚;任彦亮;韩新亚;朱秀云;洪宗琴;祝帅华;万芬;彭浩;冯玲玲;饶立;张雄 |
| 12 | 藻毒素降解酶及复合材料与应用 | 专利 | 冯玲玲;刘红林;郭小亮;程才;闫明月;何炎林 |
| 13 | 硝基苯乙烯类衍生物用于抑制果糖-1,6-二磷酸酶的用途 | 专利 | 万坚;韩新亚;陈海峰;朱昊;冯玲玲;任彦亮;池波 |
| 14 | Design, synthesis and algicides activities of thiourea derivatives as the novel scaffold aldolase inhibitors | 期刊论文 | Shan Xiao;Lin Wei;Zongqin Hong;Li Rao;Yanliang Ren;Jian Wan;Lingling Feng |
| 15 | Design, synthesis and biological evaluation of novel inhibitors against cyanobacterial pyruvate dehydrogenase multienzyme complex E1 | 期刊论文 | Jiangtao Feng;Haifeng He;Yuan Zhou;Xiaoliang Guo;Honglin Liu;Meng Cai;Fang Wang;Lingling Feng;Hongwu He |
| 16 | 苯乙酰胺类化合物的应用及杀藻剂 | 专利 | 冯玲玲;廖琴;韩强;王霞;刘红林;冯江涛;万坚 |
| 17 | 藻毒素降解酶在抑制蓝藻及降解藻毒素方面的应用 | 专利 | 冯玲玲;刘红林;郭小亮;巩小涵;万坚;冯江涛;廖琴 |
查看更多信息请先登录或注册
