针对P197L和W574L两种突变型AHAS的反抗性除草剂的设计与合成
21772058
2017
B0706.药物化学生物学
陈琼
面上项目
高级实验师
华中师范大学
66万元
除草剂;合理设计;反抗性;乙酰羟酸合成酶;多抗性位点
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Synthesis of P-chiral phosphine compounds by palladium-catalyzed C-P coupling reactions | 期刊论文 | Wang Cuiying;Yue Chang-Duo;Yuan Jia;Zheng Jia-Lian;Zhang Ying;Yu Hong;Chen Jian;Meng Sixuan;Yu Yang;Yu Guang-Ao;Che Chi-Ming |
| 2 | Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide | 期刊论文 | Qu Ren-Yu;Nan Jia-Xu;Yan Yao-Chao;Chen Qiong;Ndikuryayo Ferdinand;Wei Xue-Fang;Yang Wen-Chao;Lin Hong-Yan;Yang Guang-Fu |
| 3 | Diaryl Ether: A Privileged Scaffold for Drug and Agrochemical Discovery | 期刊论文 | Tao Chen;Hao Xiong;Jing-Fang Yang;Xiao-Lei Zhu;Ren-Yu Qu;Guang-Fu Yang |
| 4 | Synthesis of peri-Substituted (Naphthalen-1-yl)phosphine Ligands by Rhodium(I)-Catalyzed Phosphine-Directed C-H Arylation | 期刊论文 | Luo Xue;Yuan Jia;Yue Chang Duo;Zhang Zi Yang;Chen Jian;Yu Guang Ao;Che Chi Ming |
| 5 | Synthesis and Herbicidal Activity of Triketone-Aminopyridines as Potent p-Hydroxyphenylpyruvate Dioxygenase Inhibitors | 期刊论文 | Nan Jia-Xu;Yang Jing-Fang;Lin Hong-Yan;Yan Yao-Chao;Zhou Shao-Meng;Wei Xue-Fang;Chen Qiong;Yang Wen-Chao;Qu Ren-Yu;Yang Guang-Fu |
| 6 | Design, Synthesis and Bioactivity of New Pyrimidyl-salicylate Inhibitors | 期刊论文 | Qu Renyu;Yan Yaochao;Yang Jingfang;Chen Qiong;Yang Guangfu |
| 7 | Visible-Light-Promoted Transition-Metal-Free Phosphinylation of Heteroaryl Halides in the Presence of Potassium tert-Butoxide | 期刊论文 | Yuan Jia;To Wai-Pong;Zhang Zi-Yang;Yue Chang-Duo;Meng Sixuan;Chen Jian;Liu Yungen;Yu Guang-Ao;Che Chi-Ming |
| 8 | Transition-Metal-Catalyzed Regioselective Functionalization of Monophosphino-o-Carboranes | 期刊论文 | Zhang Zi-Yang;Zhang Xuepeng;Yuan Jia;Yue Chang-Duo;Meng Sixuan;Chen Jian;Yu Guang-Ao;Che Chi-Ming |
| 9 | Fragment-based discovery of flexible inhibitor targeting wild-type acetohydroxyacid synthase and P197L mutant | 期刊论文 | Qu Ren-Yu;Yang Jing-Fang;Chen Qiong;Niu Cong-Wei;Xi Zhen;Yang Wen-Chao;Yang Guang-Fu |
| 10 | Discovery of Novel Pyrazole-Quinazoline-2,4-dione Hybrids as 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors | 期刊论文 | He Bo;Wu Feng-Xu;Yu Liang-Kun;Wu Lei;Chen Qiong;Hao Ge-Fei;Yang Wen-Chao;Lin Hong-Yan;Yang Guang-Fu |
| 11 | Design, Synthesis and Biological Activity of Pyrimidyl-Salicylate Derivatives Containing Alkoxy Moiety | 期刊论文 | Qu Renyu;Cai Zhuomei;Yang Jingfang;Liu Yuchao;Chen Qiong;Niu Congwei;Xi Zhen;Yang Guangfu |
| 12 | 一种6-磺酸酯基嘧啶水杨酸类化合物及其 制备方法和应用 | 专利 | 杨光富;曲仁渝;席真;陈琼;陈杰 |
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