蓝藻II型FBAase抑制剂的生物合理设计与筛选研究

21202056
2012
B0706.药物化学生物学
任彦亮
青年科学基金项目
副教授
华中师范大学
25万元
6-二磷酸醛缩酶;II型果糖-1;合理设计;相互作用机制;蓝藻FBAase-II抑制剂
2013-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Structural and biochemical characterization of fructose-1,6/sedoheptulose-1,7-bisphosphatase from the cyanobacterium Synechocystis strain 6803 期刊论文 Wang, Weiwei|Liao, Xun|Ren, Yanliang|Hu, Xiaopeng|
2 Pharmacophore-Based Virtual Screening and Experimental Validation of Novel Inhibitors against Cyanobacterial Fructose-1,6-/Sedoheptulose-1,7-bisphosphatase 期刊论文 Ren, Yanliang|Feng, JiangTao|Xiao, San|Wan, Jian|
3 Clarifying and Illustrating the Electronic Energy Transfer Pathways in Trimeric and Hexameric Aggregation State of Cyanobacteria Allophycocyanin within the Framework of Forster Theory 期刊论文 Zhu,Hao|Feng, Lingling|Wan, Jian|Xu, Xin|
4 Design and syntheses of novel N '-((4-oxo-4H-chromen-3-yl) methylene) benzohydrazide as inhibitors of cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase 期刊论文 Ren, Yan-Liang|Ding, Ming-Wu|Feng, Ling-Ling|Wan, Jian|
5 DOX: A new computational protocol for accurate prediction of the protein–ligand binding structures 期刊论文 Ren, Yanliang|Li, Yongjian|Xu, Xin|Wan, Jian|
6 Structure-Based Design and Synthesis of Novel Dual-Target Inhibitors against Cyanobacterial Fructose-1,6-Bisphosphate Aldolase and Fructose-1,6-Bisphosphatase 期刊论文 Chen, Haifeng|Li, Yongjian|Ren, Yanliang|Wan, Jian|
7 A Rational Design, Synthesis, Biological Evaluation and Structure-Activity Relationship Study of Novel Inhibitors against Cyanobacterial Fructose-1,6-Bisphosphate Aldolase 期刊论文 Ren|Yanliang|Wan|Jian|
8 Understanding the electronic energy transfer pathways in the trimeric and hexameric aggregation state of cyanobacteria phycocyanin within the framework of forster theory 期刊论文 Zhang, Ying|Wan, Jian|Xu, Xin|Yang, Minghui|
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