D1蛋白酶抑制剂先导化合物的合理设计合成及其与靶标的分子识别作用

20672043
2006
B0706.药物化学生物学
张爱东
面上项目
教授
华中师范大学
28万元
先导化合物;分子识别;D1蛋白酶;虚拟筛选;表面等离子体共振
2007-01-01到2009-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 具有自组装功能的氨基甲酸酯类化合物的合成 期刊论文 程桂红|张爱东|涂海洋|祝丹华|
2 One-step electrochemically deposited interface of chitosan-gold nanoparticles for acetylcholinesterase biosensor design 期刊论文 Zhang, Aidong|Cai, Jie|Du, Dan|Ding, Jiawang|
3 Amperometric detection of triazophos pesticide using acetylcholinesterase biosensor based on multiwall carbon nanotube-chitosan matrix 期刊论文 Huang, Xi|Zhang, Aidong|Cai, Jie|Du, Dan|
4 Composite assembly of silver nanoparticles with avidin and biotinylated AChE on gold for the pesticidal electrochemical sensing 期刊论文 Du, Dan|Cai, Jie|Huang, Xi|Zhang, Aidong|Tu, Haiyang|Xu, Xing|Gong, Xiaojuan|
5 4-羟基-5-嘧啶甲酸乙酯衍生物的合成 期刊论文 邓灵福|黄统辉|涂海洋|张爱东|
6 Determination of carbaryl pesticide using amperometric acetylcholinesterase sensor formed by electrochemically deposited chitosan 期刊论文 Du, Dan|Cai, Jie|Ding, Jiawang|Zhang, Aidong|
7 A gold nanoparticle labeling strategy for the sensitive kinetic assay of the carbamate-acetylcholinesterase interaction by surface plasmon resonance 期刊论文 Huang, Xi|Zhang, Aidong|Tu, Haiyang|Du, Dan|Zhu, Danhua|
8 Recognition of dimethoate carried by bi-layer electrodeposition of silver nanoparticles and imprinted poly-o-phenylenediamine 期刊论文 Du, Dan|Cai, Jie|Tu, Haiyang|Chen, Shizhen|Zhang, Aidong|Tao, Yuan|
9 Application of multiwalled carbon nanotubes for solid-phase extraction of organophosphate pesticide 期刊论文 Zhang, Aidong|Zhang, Jianming|Du, Dan|Cai, He|Wang, Minghui|Tu, Haiyang|
10 Acetylcholinesterase Biosensor Based on Gold Nanoparticles and Cysteamine Self Assembled Monolayer for Determination of Monocrotophos 期刊论文 Tu, Haiyang|Cai, Jie|Du, Dan|Zhang, Jianming|Chen, Wenjuan|Zhang, Aidong|
11 Stripping voltammetric analysis of organophosphate pesticides based on solid-phase extraction at zirconia nanoparticles modified electrode 期刊论文 Ye, Xiuping|Liu, Deli|Zhang, Jiande|Tu, Haiyang|Du, Dan|Zhang, Aidong|Zeng, Yan|
12 Rapid determination of triazophos using acetylcholinesterase biosensor based on sol-gel interface assembling muldwall carbon nanotubes 期刊论文 Cai, Jie|Du, Dan|Zhang, Aidong|Song, Dandan|
13 Immobilization of acetylcholinesterase based on the controllable adsorption of carbon nanotubes onto an alkanethiol monolayer for carbaryl sensing 期刊论文 Cai, Jie|Tao, Yuan|Tu, Haiyang|Wang, Minghui|Du, Dan|Zhang, Aidong|
14 An amperometric acetylthiocholine sensor based on immobilization of acetylcholinesterase on a multiwall carbon nanotube-cross-linked chitosan composite 期刊论文 Ding, Jiawang|Zhang, Aidong|Cai, Jie|Chen, Shizhen|Huang, Xi|Du, Dan|
15 Comparison of pesticide sensitivity by electrochemical test based on acetylcholinesterase biosensor 期刊论文 Cai, He|Du, Dan|Huang, Xi|Zhang, Aidong|
16 Synthesis and Herbicidal Activities of Novel 4-(4-(5-methyl-3-arylisoxazol-4-yl)thiazol-2-yl)piperidyl Carboxamides and Thiocarboxamides 期刊论文 Liu, Su-Fang|Zhang, Ai-Dong|Huang, Tong-Hui|Tu, Hai-Yang|Hu, De-Jin|
17 Electrochemical pesticide sensitivity test using acetylcholinesterase biosensor based on colloidal gold nanoparticle modified sol-gel interface 期刊论文 Zhang, Aidong|Du, Dan|Chen, Shizhen|Cai, Jie|
18 N-Phenyl-4-(8-phenyl-4,5-dihydro-1,2-benzoxazolo[4,5-d]thiazol-2-yl)pipe ridine-1-carboxamide 期刊论文 Tu, Hai-Yang|Liu, Ming|Hu, De-Jin|Zhang, Ai-dong|Huang, Tong-Hui|
19 Immobilization of acetylcholinesterase on gold nanoparticles embedded in sol-gel film for amperometric detection of organophosphorous insecticide 期刊论文 Du, Dan|Cai, Jie|Zhang, Aidong|Chen, Shizhen|
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