基于稀疏概率图模型的多癌症多组学生物网络构建方法研究

11871026
2018
A0604.生物与生命科学中的数学
张晓飞
面上项目
教授
华中师范大学
53万元
共表达关系;蛋白质-蛋白质相互作用;基因表达谱数据;相似性分析;机器学习
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Sparse regularized low-rank tensor regression with applications in genomic data analysis 期刊论文 Le Ou-Yang;Xiao-Fei Zhang;Hong Yan
2 Time-varying differential network analysis for revealing network rewiring over cancer progression 期刊论文 Ting Xu;Le Ou-Yang;Hong Yan;Xiao-Fei Zhang
3 A graph regularized generalized matrix factorization model for predicting links in biomedical bipartite networks 期刊论文 Zi-Chao Zhang;Xiao-Fei Zhang;Min Wu;Le Ou-Yang;Xing-Ming Zhao;Xiao-Li Li
4 scTSSR2: imputing dropout events for single-cell RNA sequencing using fast two-side self-representation 期刊论文 Bo Li;Ke Jin;Le Ou-Yang;Hong Yan;Xiao-Fei Zhang
5 A joint graphical model for inferring gene networks across multiple subpopulations and data types 期刊论文 Xiao-Fei Zhang;Le Ou-Yang;Ting Yan;Xiaohua Hu;Hong Yan
6 scTSSR: gene expression recovery for single-cell RNA sequencing using two-side sparse self-representation 期刊论文 Ke Jin;Le Ou-Yang;Xing-Ming Zhao;Hong Yan;Xiao-Fei Zhang
7 Inferring gene co-expression networks by incorporating prior protein-protein interaction networks 期刊论文 Meng-Guo Wang;Le Ou-Yang;Hong Yan;Xiao-Fei Zhang
8 EnImpute: imputing dropout events in single-cell RNA-sequencing data via ensemble learning 期刊论文 Xiao-Fei Zhang;Le Ou-Yang;Shuo Yang;Xing-Ming Zhao;Xiaohua Hu;Hong Yan
9 Differential network analysis via weighted fused conditional Gaussian graphical model 期刊论文 Le Ou-Yang;Xiao-Fei Zhang;Xiaohua Hu;Hong Yan
10 scDEA: differential expression analysis in single-cell RNA-sequencing data via ensemble learning 期刊论文 Hui-Sheng Li;Le Ou-Yang;Yuan Zhu;Hong Yan;Xiao-Fei Zhang
11 WDNE: an integrative graphical model for inferring differential networks from multi-platform gene expression data with missing values 期刊论文 Le Ou-Yang;Dehan Cai;Xiao-Fei Zhang;Hong Yan
12 EnDecon: cell type deconvolution of spatially resolved transcriptomics data via ensemble learning 期刊论文 Jia-Juan Tu;Hui-Sheng Li;Hong Yan;Xiao-Fei Zhang
13 Identifying gene network rewiring based on partial correlation 期刊论文 Yu-Ting Tan;Le Ou-Yang;Xingpeng Jiang;Hong Yan;Xiao-Fei Zhang
14 Differential network analysis by simultaneously considering changes in gene interactions and gene expression 期刊论文 Jia-Juan Tu;Le Ou-Yang;Yuan Zhu;Hong Yan;Hong Qin;Xiao-Fei Zhang
15 Imputing dropouts for single-cell RNA sequencing based on multi-objective optimization 期刊论文 Ke Jin;Bo Li;Hong Yan;Xiao-Fei Zhang
16 Joint reconstruction of multiple gene networks by simultaneously capturing inter-tumor and intra-tumor heterogeneity 期刊论文 Jia-Juan Tu;Le Ou-Yang;Hong Yan;Xiao-Fei Zhang;Hong Qin
17 Identifying gene network rewiring using robust differential graphical model with multivariate t-distribution 期刊论文 Rui Yuan;Le Ou-Yang;Xiaohua Hu;Xiao-Fei Zhang
18 DiffNetFDR: differential network analysis with false discovery rate control 期刊论文 Xiao-Fei Zhang;Le Ou-Yang;Shuo Yang;Xiaohua Hu;Hong Yan
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