新策略化学合成膜蛋白及其动态生物物理研究

21402206
2014
B0702.生物分子的化学生物学
郑基深
青年科学基金项目
教授
中国科学院合肥物质科学研究院
25万元
膜蛋白化学合成;蛋白质翻译后修饰;Ser/Thr位点可逆骨架修饰;动态生物物理研究;定点同位素标记
2015-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Efficient synthesis of longer A beta peptides via removable backbone modification 期刊论文 Zuo Chao;Tang Shan;Si Yan-Yan;Wang Zhipeng A.;Tian Chang-Lin;Zheng Ji-Shen
2 Protein/peptide secondary structural mimics: design, characterization, and modulation of protein-protein interactions 期刊论文 Wang Zhipeng A.;Ding Xiaozhe Z.;Tian Chang-Lin;Zheng Ji-Shen
3 Convergent Total Synthesis of Histone H2B Protein with Site-Specific Ubiquitination at Lys120 期刊论文 Qi Yun-Kun;He Qiao-Qiao;Ai Hua-Song;Li Jia-Bin;Zheng Ji-Shen
4 Chemical Synthesis of Diubiquitin-Based Photoaffinity Probes for Selectively Profiling Ubiquitin-Binding Proteins 期刊论文 Liang Jun;Zhang Lin;Tan Xiang-Long;Qi Yun-Kun;Feng Shan;Deng Haiteng;Yan Yijing;Zheng Ji-Shen;Liu Lei;Tian Chang-Lin
5 Robust Chemical Synthesis of Membrane Proteins through a General Method of Removable Backbone Modification 期刊论文 Zheng Ji-Shen;He Yao;Zuo Chao;Cai Xiao-Ying;Tang Shan;Wang Zhipeng A.;Zhang Long-Hua;Tian Chang-Lin;Liu Lei
6 Total synthesis of mambalgin-1/2/3 by two-segment hydrazide-based native chemical ligation 期刊论文 Lan Huan;Wu Kun;Zheng Yong;Pan Man;Huang Yi-Chao;Gao Shuai;Zheng Qing-Yun;Zheng Ji-Shen;Li Yi-Ming;Xiao Bailong;Liu Lei
7 Total chemical synthesis of the site-selective azide-labeled [I66A]HIV-1 protease 期刊论文 Qi Yun-Kun;Chang Hao-Nan;Pan Kai-Mai;Tian Chang-Lin;Zheng Ji-Shen
8 Removable Backbone Modification Method for the Chemical Synthesis of Membrane Proteins 期刊论文 Li Jia-Bin;Tang Shan;Zheng Ji-Shen;Tian Chang-Lin;Liu Lei
9 Hmboff/onas a switchable thiol protecting group for native chemical ligation 期刊论文 Qi Yun-Kun;Tang Shan;Huang Yi-Chao;Pan Man;Zheng Ji-Shen;Liu Lei
10 An Fmoc-compatible method for synthesis of peptides containing photocaged aspartic acid or glutamic acid 期刊论文 Tang Shan;Cheng Jing-Yuan;Zheng Ji-Shen
11 A new strategy for total solid-phase synthesis of polymyxins 期刊论文 Xu Wei-Liang;Cui A-Long;Hu Xin-Xin;You Xue-Fu;Li Zhuo-Rong;Zheng Ji-Shen
12 The Structural Designs and Property Analysis of Polyamide Based Structures as Peptide Secondary Structure Mimics 期刊论文 Wang Zhipeng A.;Tian Changlini;Zheng Jishen
13 Chemical synthesis of membrane proteins by the removable backbone modification method 期刊论文 Tang Shan;Zuo Chao;Huang Dong-Liang;Cai Xiao-Ying;Zhang Long-Hua;Tian Chang-Lin;Zheng Ji-Shen;Liu Lei
14 The recent developments and applications of the traceless-Staudinger reaction in chemical biology study 期刊论文 Wang Zhi-Peng A.;Tian Chang-Lin;Zheng Ji-Shen
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